Saeed Hamid
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View article: Synthesising key findings from Indonesia’s first civil society-led forum on primary health care: PHC forum, Jakarta, 13-14 November 2023
Synthesising key findings from Indonesia’s first civil society-led forum on primary health care: PHC forum, Jakarta, 13-14 November 2023 Open
Background Despite evidence showing the important role of a robust primary health care (PHC) in achieving health equity, many nations still need strong, directional policies and unyielding commitments to strengthening PHC after the Astana …
View article: Functional Amyloids in Adhesion of Non-albicans Candida Species
Functional Amyloids in Adhesion of Non-albicans Candida Species Open
Candida fungal species are the most common fungal opportunistic pathogens. Their ability to form antifungal resistant biofilms contributes to their increasing clinical frequency. These fungi express surface-anchored adhesins including memb…
View article: Hepatitis B virus resistance to nucleos(t)ide analogue therapy: WHO consultation on questions, challenges, and a roadmap for the field
Hepatitis B virus resistance to nucleos(t)ide analogue therapy: WHO consultation on questions, challenges, and a roadmap for the field Open
In this Review, we summarise outputs from a multidisciplinary consultation convened by WHO between July 11 and 13, 2023, to discuss hepatitis B virus (HBV) drug resistance (HBVDR). Treatment of chronic HBV infection with highly effective n…
View article: Morphology, Age, and Growth of Triplophysa strauchii in Sayram Lake, Xinjiang, China
Morphology, Age, and Growth of Triplophysa strauchii in Sayram Lake, Xinjiang, China Open
This study focused on T. strauchii in Sayram Lake, Xinjiang. In August 2023, a total of 768 samples were collected to investigate its morphological, age, and growth characteristics. T. strauchii has an elongated body with a slightly raised…
View article: Effects of Water Temperature, Light Intensities and Photoperiod on the Survival and Growth of Juvenile Schizothorax irregularis and Diptychus maculates
Effects of Water Temperature, Light Intensities and Photoperiod on the Survival and Growth of Juvenile Schizothorax irregularis and Diptychus maculates Open
An experimental ecological method was used to study the effects of water temperature, photoperiod, and light intensity on the survival, feeding, and growth of juvenile Schizothorax irregularis and Diptychus maculates. The Box–Benhnken expe…
View article: Global Burden of Major Chronic Liver Diseases in 2021
Global Burden of Major Chronic Liver Diseases in 2021 Open
Background This study utilised the Global Burden of Disease data (2010–2021) to analyse the rates and trends in point prevalence, annual incidence and years lived with disability (YLDs) for major chronic liver diseases, such as hepatitis B…
View article: Morphological Difference Analysis of Triplophysa strauchii from Different Geographical Populations in Xinjiang, China
Morphological Difference Analysis of Triplophysa strauchii from Different Geographical Populations in Xinjiang, China Open
Spotted stone loach (Triplophysa strauchii), a common fish species in Xinjiang, China, is ecologically pivotal within the local ecosystem; regrettably, human-induced factors like habitat destruction, pollution, and overfishing have gravely…
View article: Number of people treated for hepatitis C virus infection in 2014-2023 and applicable lessons for new HBV and HDV therapies
Number of people treated for hepatitis C virus infection in 2014-2023 and applicable lessons for new HBV and HDV therapies Open
Long-term hepatitis C virus (HCV) infection can lead to cirrhosis and liver cancer. Since 2014, these infections can be effectively treated with 8-12 weeks of oral therapies. In 2015, the World Health Organization established targets to el…
View article: Assessing pricing and affordability of HBV treatment in Asia–Pacific region: a barrier to elimination
Assessing pricing and affordability of HBV treatment in Asia–Pacific region: a barrier to elimination Open
Background The Asia–Pacific (AP) region carries a substantial burden of HBV. Affordable HBV treatment is crucial to attain WHO’s elimination goal. This study assesses the pricing and affordability of HBV treatment in AP. Methods A survey c…
View article: Hepatitis C virus cascade of care among adults in Sindh province, Pakistan: Findings from 2019-2020 household sero-survey.
Hepatitis C virus cascade of care among adults in Sindh province, Pakistan: Findings from 2019-2020 household sero-survey. Open
Pakistan has the largest national burden of hepatitis C virus (HCV) infections (9.8 million). High levels of testing and treatment are needed to achieve HCV elimination, but little data exists on this in Pakistan. A household sero-survey f…
View article: Overview of Hepatitis C Elimination Efforts in Pakistan and the Launch of Prime Minister’s Programme for the Elimination of Hepatitis C
Overview of Hepatitis C Elimination Efforts in Pakistan and the Launch of Prime Minister’s Programme for the Elimination of Hepatitis C Open
Hepatitis B and C are serious viral infections that cancause liver damage and death. According to the WorldHealth Organization (WHO), there are currently 2.8 millionpeople living with hepatitis B in Pakistan, and 9.8 millionpeople living w…
View article: Usability and acceptability of self-testing for hepatitis C virus exposure in a high-prevalence urban informal settlement in Karachi, Pakistan
Usability and acceptability of self-testing for hepatitis C virus exposure in a high-prevalence urban informal settlement in Karachi, Pakistan Open
Background Hepatitis C virus (HCV) antibody self-testing (HCVST) may help expand screening access and support HCV elimination efforts. Despite potential benefits, HCVST is not currently implemented in Pakistan. This study aimed to assess t…
View article: Changes in the prevalence of hepatitis B and C viral infections in Sindh province, Pakistan: Findings from two sero‐surveys in 2007 and 2019
Changes in the prevalence of hepatitis B and C viral infections in Sindh province, Pakistan: Findings from two sero‐surveys in 2007 and 2019 Open
Pakistan harbours a large burden of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. We utilised repeat sero‐surveys to assess progress achieved towards hepatitis elimination in Pakistan. Multilevel logistic regression evalua…
View article: Correction: Health and economic benefits of achieving hepatitis C virus elimination in Pakistan: A modelling study and economic analysis
Correction: Health and economic benefits of achieving hepatitis C virus elimination in Pakistan: A modelling study and economic analysis Open
[This corrects the article DOI: 10.1371/journal.pmed.1003818.].
View article: Estimating the prevalence of hepatitis delta virus infection among adults in the United States: A meta‐analysis
Estimating the prevalence of hepatitis delta virus infection among adults in the United States: A meta‐analysis Open
Background and Aims Suboptimal awareness and low rates of hepatitis delta virus (HDV) testing contribute to underdiagnosis and gaps in accurate estimates of U.S. HDV prevalence. We aim to provide an updated assessment of HDV prevalence in …
View article: Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients Open
The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not clearly established. This study aimed to evaluate the association between ammonia levels and LRCs in patients …