Saemi Park
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View article: <scp>CREST</scp>‐<scp>UK</scp>: Real‐world effectiveness, safety and outpatient delivery of <scp>CPX</scp>‐351 for first‐line treatment of newly diagnosed therapy‐related <scp>AML</scp> and <scp>AML</scp> with myelodysplasia‐related changes in the <scp>UK</scp>
<span>CREST</span>‐<span>UK</span>: Real‐world effectiveness, safety and outpatient delivery of <span>CPX</span>‐351 for first‐line treatment of newly diagnosed therapy‐related <span>AML</span> and <span>AML</span> with myelodysplasia‐related changes in the <span>UK</span> Open
Summary Favourable outcomes with CPX‐351 versus conventional 7 + 3 were demonstrated in the pivotal phase III trial in adults aged 60–75 years with newly diagnosed, highrisk/secondary acute myeloid leukaemia (AML). As a complement to the c…
View article: Exploring Embryo-Ototoxic Effects: Insights into Deodorant-Induced Hair Cell Damage in Zebrafish
Exploring Embryo-Ototoxic Effects: Insights into Deodorant-Induced Hair Cell Damage in Zebrafish Open
Our study investigated the embryo-ototoxic effects of deodorant2 (DA2) on zebrafish embryos, which serve as valuable model organisms due to genetic and physiological similarities to humans. We focused on understanding DA2’s impact on zebra…
View article: P486: REAL-WORLD EFFECTIVENESS AND SAFETY OF CPX-351 IN PATIENTS AGED <60 AND ≥60 YEARS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA: CREST-UK POST-HOC ANALYSIS
P486: REAL-WORLD EFFECTIVENESS AND SAFETY OF CPX-351 IN PATIENTS AGED <60 AND ≥60 YEARS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA: CREST-UK POST-HOC ANALYSIS Open
Background: Favorable survival outcomes with CPX-351 vs conventional 7 + 3 and comparable safety in adults aged 60–75 years in the pivotal phase 3 trial (NCT01696084) led to the approval of CPX-351 for newly diagnosed therapy-related acute…
View article: Neighborhood Disorder and Health-Related Work Absences: Perceived Control and Neighborhood Trust as Explanatory Mechanisms
Neighborhood Disorder and Health-Related Work Absences: Perceived Control and Neighborhood Trust as Explanatory Mechanisms Open
The current research argues that people residing in disordered neighborhoods will tend not to trust their neighbors and perceive less control over life, which will in turn increase the risk of health-related work absences. Researchers also…
View article: A Comprehensive Characterization of Temporal Rheotactic Behaviors in Lateral Line Damaged Zebrafish Larvae
A Comprehensive Characterization of Temporal Rheotactic Behaviors in Lateral Line Damaged Zebrafish Larvae Open
View article: Short-term Efficacy of Intravitreal Aflibercept Therapy for Diabetic Macular Edema
Short-term Efficacy of Intravitreal Aflibercept Therapy for Diabetic Macular Edema Open
서론 당뇨병은 전 세계적으로 그 유병률이 증가하는 추세로, 당뇨병 과 관련된 대표적인 눈 합병증인 당뇨망막병증은 아시아태평양 지역에서 심각한 시력저하의 주된 원인 중 하나로 알려져 있다 [1,2].국내 조사 결과에 따르면 당뇨 환자의 약 15.8%에서 당뇨 망막병증을 동반하는 것으로 나타났다[3].당뇨황반부종은 당뇨망막병증이 있는 환자에서 시력저하를 유발할 수 있는 중요한 원인이며, 이러한 황반부종의 감소를 위 하여 국소 레…
View article: Circadian and cardiovascular dysfunction in the Huntington’s disease mouse models
Circadian and cardiovascular dysfunction in the Huntington’s disease mouse models Open
Circadian and sleep disruptions have been shown to lead to an increased risk for cardiovascular (CV) events. Huntington’s disease (HD) patients are reported to have various symptoms including circadian and motor deficits. In addition, CV s…
View article: Evaluation of Ototoxicity of an Antifog Agent and the Suspected Underlying Mechanisms: An Animal Study
Evaluation of Ototoxicity of an Antifog Agent and the Suspected Underlying Mechanisms: An Animal Study Open
Use of rigid endoscopes has become widespread in middle ear surgeries, thereby attracting attention to the safety of antifog agents. However, few studies on the ototoxicity of antifog agents have been conducted. The purpose of this study w…
View article: Correction to: Intravitreal bevacizumab injections combined with laser photocoagulation for adult-onset Coats’ disease
Correction to: Intravitreal bevacizumab injections combined with laser photocoagulation for adult-onset Coats’ disease Open