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View article: Correction: In Vivo Evaluation of Almotriptan Malate Formulation Through Intranasal Route for the Treatment of Migraine: Systematic Development and Pharmacokinetic Assessment
Correction: In Vivo Evaluation of Almotriptan Malate Formulation Through Intranasal Route for the Treatment of Migraine: Systematic Development and Pharmacokinetic Assessment Open
View article: Protein-Bound Nano-Injectable Suspension: Unveiling the Promises and Challenges
Protein-Bound Nano-Injectable Suspension: Unveiling the Promises and Challenges Open
Protein-bound nano-injectable solutions represent a cutting-edge advancement in nanomedicine, offering a versatile platform for precise and controlled drug delivery. By leveraging the biocompatibility and functional versatility of proteins…
View article: Vaccine adjuvants for immunotherapy: type, mechanisms and clinical applications
Vaccine adjuvants for immunotherapy: type, mechanisms and clinical applications Open
Immunotherapy has emerged as a powerful approach in treating various diseases, yet its success often hinges on the efficacy of adjuvants, agents that boost immune responses to therapeutic targets. Traditional adjuvants have offered foundat…
View article: Referee report. For: Forecasting in vivo pharmacokinetics of metformin HCl floating beads using Gastroplus® PBPK [version 2; peer review: 1 approved, 1 approved with reservations]
Referee report. For: Forecasting in vivo pharmacokinetics of metformin HCl floating beads using Gastroplus® PBPK [version 2; peer review: 1 approved, 1 approved with reservations] Open
View article: Review of: "Selection of Bone-Targeting Peptides for Therapeutic Intervention: An In Vivo Evaluation and Comparison Study"
Review of: "Selection of Bone-Targeting Peptides for Therapeutic Intervention: An In Vivo Evaluation and Comparison Study" Open
View article: Recent Review on Biological Barriers and Host–Material Interfaces in Precision Drug Delivery: Advancement in Biomaterial Engineering for Better Treatment Therapies
Recent Review on Biological Barriers and Host–Material Interfaces in Precision Drug Delivery: Advancement in Biomaterial Engineering for Better Treatment Therapies Open
Preclinical and clinical studies have demonstrated that precision therapy has a broad variety of treatment applications, making it an interesting research topic with exciting potential in numerous sectors. However, major obstacles, such as…
View article: Advanced Characterization and Sample Preparation Strategies for Nanoformulations
Advanced Characterization and Sample Preparation Strategies for Nanoformulations Open
The escalating impact and remarkable progress of nanotechnology have shifted the paradigms of medicine and the healthcare system. Nanosystems have emerged, extensively holding the potential to advance disease diagnosis and treatment specif…
View article: Receptor-Targeted Nanomedicine for Cancer Therapy
Receptor-Targeted Nanomedicine for Cancer Therapy Open
Receptor-targeted drug delivery has been extensively explored for active targeting of therapeutic moiety in cancer treatment. In this review, we discuss the receptors that are overexpressed on tumor cells and have the potential to be targe…
View article: Achieving Endo/Lysosomal Escape Using Smart Nanosystems for Efficient Cellular Delivery
Achieving Endo/Lysosomal Escape Using Smart Nanosystems for Efficient Cellular Delivery Open
The delivery of therapeutic agents faces significant hurdles posed by the endo-lysosomal pathway, a bottleneck that hampers clinical effectiveness. This comprehensive review addresses the urgent need to enhance cellular delivery mechanisms…
View article: Antitoxin nanoparticles: design considerations, functional mechanisms, and applications in toxin neutralization
Antitoxin nanoparticles: design considerations, functional mechanisms, and applications in toxin neutralization Open
The application of nanotechnology has significantly advanced the development of novel platforms that enhance disease treatment and diagnosis. A key innovation in this field is the creation of antitoxin nanoparticles (ATNs), designed to add…
View article: Referee report. For: Exploring the Synergistic Potential of Pectin-Chitosan Composites for Advanced Drug Delivery and Biomedical Implant Applications: A Comprehensive Review and Future Perspectives [version 1; peer review: 1 approved with reservations, 1 not approved]
Referee report. For: Exploring the Synergistic Potential of Pectin-Chitosan Composites for Advanced Drug Delivery and Biomedical Implant Applications: A Comprehensive Review and Future Perspectives [version 1; peer review: 1 approved with reservations, 1 not approved] Open
View article: Collagen-Based Hydrogels for the Eye: A Comprehensive Review
Collagen-Based Hydrogels for the Eye: A Comprehensive Review Open
Collagen-based hydrogels have emerged as a highly promising platform for diverse applications in ophthalmology, spanning from drug delivery systems to biomedical interventions. This review explores the diverse sources of collagen, which gi…
View article: Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy
Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy Open
Glioblastoma is one of the most devastating central nervous system disorders. Being a highly vascular brain tumor, it is distinguished by aberrant vessel architecture. This lends credence to the idea that endothelial cells (ECs) linked wit…
View article: “Bioinspired” Membrane-Coated Nanosystems in Cancer Theranostics: A Comprehensive Review
“Bioinspired” Membrane-Coated Nanosystems in Cancer Theranostics: A Comprehensive Review Open
Achieving precise cancer theranostics necessitates the rational design of smart nanosystems that ensure high biological safety and minimize non-specific interactions with normal tissues. In this regard, “bioinspired” membrane-coated nanosy…
View article: Versatility of Liposomes for Antisense Oligonucleotide Delivery: A Special Focus on Various Therapeutic Areas
Versatility of Liposomes for Antisense Oligonucleotide Delivery: A Special Focus on Various Therapeutic Areas Open
Nucleic acid therapeutics, specifically antisense oligonucleotides (ASOs), can effectively modulate gene expression and protein function, leading to long-lasting curative effects. The hydrophilic nature and large size of oligonucleotides p…
View article: Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications
Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications Open
Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has surfaced as a material of promise for drug delivery and biomedical applications. Different chitin and chitosan extraction techniques can produce materials …
View article: Emerging Trends in Lipid-Based Vaccine Delivery: A Special Focus on Developmental Strategies, Fabrication Methods, and Applications
Emerging Trends in Lipid-Based Vaccine Delivery: A Special Focus on Developmental Strategies, Fabrication Methods, and Applications Open
Lipid-based vaccine delivery systems such as the conventional liposomes, virosomes, bilosomes, vesosomes, pH-fusogenic liposomes, transferosomes, immuno-liposomes, ethosomes, and lipid nanoparticles have gained a remarkable interest in vac…
View article: Decoding Artificial Intelligence in Neuroscience: Applications Beyond Diagnosis
Decoding Artificial Intelligence in Neuroscience: Applications Beyond Diagnosis Open
Background: Artificial Intelligence has witnessed exponential expansion in health care applications. The article pronounces the dynamic excellence AI is achieving in the healthcare discipline of neuroscience. Objective: The paper highlight…
View article: Peptide Engraftment on PEGylated Nanoliposomes for Bone Specific Delivery of PTH (1-34) in Osteoporosis
Peptide Engraftment on PEGylated Nanoliposomes for Bone Specific Delivery of PTH (1-34) in Osteoporosis Open
Bone-specific functionalization strategies on liposomes are promising approaches to delivering the drug in osteoporotic conditions. This approach delivers the drug to the bone surface specifically, reduces the dose and off-target effects o…
View article: Functionalized Carbon Nanotubes for Cell Tracking
Functionalized Carbon Nanotubes for Cell Tracking Open
Carbon nanotubes owing to their attributes of high surface area, unique needle-like structure, and capability of circumventing the physical and biochemical blockage of the blood-brain barrier are extensively explored for theragnostic appli…
View article: Tumor-derived systems as novel biomedical tools—turning the enemy into an ally
Tumor-derived systems as novel biomedical tools—turning the enemy into an ally Open
Cancer is a complex illness that presents significant challenges in its understanding and treatment. The classic definition, "a group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body," fails to …
View article: Anabolic Peptide-Enriched Stealth Nanoliposomes for Effective Anti-Osteoporotic Therapy
Anabolic Peptide-Enriched Stealth Nanoliposomes for Effective Anti-Osteoporotic Therapy Open
The objective of the present work was to develop PTH (1-34)-loaded stealth nanoliposomes (PTH-LPs) by employing the use of the Quality by Design (QbD) approach. Risk identification was carried out using the Ishikawa fishbone diagram. PTH-L…
View article: Polysaccharide Based Implantable Drug Delivery: Development Strategies, Regulatory Requirements, and Future Perspectives
Polysaccharide Based Implantable Drug Delivery: Development Strategies, Regulatory Requirements, and Future Perspectives Open
Implantable drug delivery systems advocate a wide array of potential benefits, including effective administration of drugs at lower concentrations and fewer side-effects whilst increasing patient compliance. Amongst several polymers used f…
View article: A State-of-the-Art Review on Opioids Induced Constipation and itsManagement
A State-of-the-Art Review on Opioids Induced Constipation and itsManagement Open
Background: Pain is a complex physiological and psychological response to a noxious stimulus, sometimes deteriorating a patient’s quality of life. Opioids remain the mainstay treatment modality for chronic pain. Several concerns are raised…