Sage R. Myers
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View article: Transient albuminuria in the setting of short-term severe hyperglycemia in type 1 diabetes
Transient albuminuria in the setting of short-term severe hyperglycemia in type 1 diabetes Open
View article: Head Injury Treatment With Healthy and Advanced Dietary Supplements: A Pilot Randomized Controlled Trial of the Tolerability, Safety, and Efficacy of Branched Chain Amino Acids in the Treatment of Concussion in Adolescents and Young Adults
Head Injury Treatment With Healthy and Advanced Dietary Supplements: A Pilot Randomized Controlled Trial of the Tolerability, Safety, and Efficacy of Branched Chain Amino Acids in the Treatment of Concussion in Adolescents and Young Adults Open
Concussion is a common injury in the adolescent and young adult populations. Although branched chain amino acid (BCAA) supplementation has shown improvements in neurocognitive and sleep function in pre-clinical animal models of mild-to-mod…
View article: Pediatric capacity crisis: A framework and strategies to prepare for a pediatric surge
Pediatric capacity crisis: A framework and strategies to prepare for a pediatric surge Open
A pediatric capacity crisis developed across the country in the Fall and Winter of 2022 due to a combination of factors, including a surge in respiratory viruses, staffing shortages, and historical closures of inpatient pediatric units. Th…
View article: Rehydration Rates and Outcomes in Overweight Children With Diabetic Ketoacidosis
Rehydration Rates and Outcomes in Overweight Children With Diabetic Ketoacidosis Open
BACKGROUND AND OBJECTIVES The Pediatric Emergency Care Applied Research Network Fluid Therapies Under Investigation in Diabetic Ketoacidosis (DKA) (FLUID) Trial found that rapid fluid infusion does not increase the risk of cerebral injury.…
View article: Stratification of risk for emergent intracranial abnormalities in children with headaches: a Pediatric Emergency Care Applied Research Network (PECARN) study protocol
Stratification of risk for emergent intracranial abnormalities in children with headaches: a Pediatric Emergency Care Applied Research Network (PECARN) study protocol Open
Introduction Headache is a common chief complaint of children presenting to emergency departments (EDs). Approximately 0.5%–1% will have emergent intracranial abnormalities (EIAs) such as brain tumours or strokes. However, more than one-th…
View article: Emergency Department Presentations of Diabetic Ketoacidosis in a Large Cohort of Children
Emergency Department Presentations of Diabetic Ketoacidosis in a Large Cohort of Children Open
Background. Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of childhood diabetes. However, the influence of demographic factors on presentation are not well-defined. Methods. We included children from 12 centers…
View article: Short-Course Therapy for Urinary Tract Infections in Children
Short-Course Therapy for Urinary Tract Infections in Children Open
Importance There is a paucity of pediatric-specific comparative data to guide duration of therapy recommendations in children with urinary tract infection (UTI). Objective To compare the efficacy of standard-course and short-course therapy…
View article: Variability in firearm injury among major pediatric trauma centers across the USA
Variability in firearm injury among major pediatric trauma centers across the USA Open
Objectives In 2020, firearm injuries surpassed automobile collisions as the leading cause of death in US children. Annual automobile fatalities have decreased during 40 years through a multipronged approach. To develop similarly targeted p…
View article: Clinical and Laboratory Predictors of Dehydration Severity in Children With Diabetic Ketoacidosis
Clinical and Laboratory Predictors of Dehydration Severity in Children With Diabetic Ketoacidosis Open
Most children with DKA have mild-to-moderate dehydration. Although biochemical measures were more closely associated with the severity of dehydration than clinical assessments, neither were sufficiently predictive to inform rehydration pra…
View article: Trauma-informed and family-centered paediatric resuscitation: Defining domains and practices
Trauma-informed and family-centered paediatric resuscitation: Defining domains and practices Open
View article: The effect of hand position on chest compression quality during CPR in young children: Findings from the Videography in Pediatric Resuscitation (VIPER) collaborative
The effect of hand position on chest compression quality during CPR in young children: Findings from the Videography in Pediatric Resuscitation (VIPER) collaborative Open
In infants, 1H resulted in greater CC depth than 2 T. In children 1 to 8 yo, 2H resulted in greater depth than 1H.. These data suggest that different hand position during CPR in young children from what is currently recommended may result …
View article: Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes
Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes Open
Introduction Young children with type 1 diabetes (T1D) may be at particularly high risk of cognitive decline following diabetic ketoacidosis (DKA). However, studies of cognitive functioning in T1D typically examine school‐age children. The…
View article: Relationships among biochemical measures in children with diabetic ketoacidosis
Relationships among biochemical measures in children with diabetic ketoacidosis Open
Objectives Investigating empirical relationships among laboratory measures in children with diabetic ketoacidosis (DKA) can provide insights into physiological alterations occurring during DKA. We determined whether alterations in laborato…
View article: Pyuria in Children with Diabetic Ketoacidosis
Pyuria in Children with Diabetic Ketoacidosis Open
View article: Clinical Characteristics of Children with Cerebral Injury preceding Treatment of Diabetic Ketoacidosis
Clinical Characteristics of Children with Cerebral Injury preceding Treatment of Diabetic Ketoacidosis Open
Previous studies have identified more severe acidosis and higher blood urea nitrogen (BUN) as risk factors for cerebral injury during treatment of diabetic ketoacidosis (DKA) in children; however, cerebral injury also can occur before DKA …
View article: Traumatic injury clinical trial evaluating tranexamic acid in children (<scp>TIC‐TOC</scp>): A pilot randomized trial
Traumatic injury clinical trial evaluating tranexamic acid in children (<span>TIC‐TOC</span>): A pilot randomized trial Open
Background The antifibrinolytic drug tranexamic acid (TXA) improves survival in adults with traumatic hemorrhage; however, the drug has not been evaluated in a trial in injured children. We assessed the feasibility of a large‐scale trial e…
View article: Videographic Assessment of Tracheal Intubation Technique in a Network of Pediatric Emergency Departments: A Report by the Videography in Pediatric Resuscitation (VIPER) Collaborative
Videographic Assessment of Tracheal Intubation Technique in a Network of Pediatric Emergency Departments: A Report by the Videography in Pediatric Resuscitation (VIPER) Collaborative Open
View article: Association of Acute Kidney Injury During Diabetic Ketoacidosis With Risk of Microalbuminuria in Children With Type 1 Diabetes
Association of Acute Kidney Injury During Diabetic Ketoacidosis With Risk of Microalbuminuria in Children With Type 1 Diabetes Open
These data demonstrate that episodes of AKI occurring during DKA in children with type 1 diabetes are significantly associated with risk of developing microalbuminuria. Greater efforts are necessary to reduce the frequency of DKA.
View article: Enrollment with and without exception from informed consent in a pilot trial of tranexamic acid in children with hemorrhagic injuries
Enrollment with and without exception from informed consent in a pilot trial of tranexamic acid in children with hemorrhagic injuries Open
Background Federal exception from informed consent (EFIC) procedures allow studies to enroll patients with time‐sensitive, life‐threatening conditions when written consent is not feasible. Our objective was to compare enrollment rates with…
View article: Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis
Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis Open
OBJECTIVE Fluid replacement to correct dehydration, acidosis, and electrolyte abnormalities is the cornerstone of treatment for diabetic ketoacidosis (DKA), but little is known about optimal fluid infusion rates and electrolyte content. Th…
View article: Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis
Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis Open
IMPORTANCE: Fluid replacement to correct dehydration, acidosis and electrolyte abnormalities is the cornerstone of treatment for diabetic ketoacidosis (DKA) but little is known about optimal fluid infusion rates and electrolyte cont…
View article: Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis
Effects of Fluid Rehydration Strategy on Correction of Acidosis and Electrolyte Abnormalities in Children With Diabetic Ketoacidosis Open
IMPORTANCE: Fluid replacement to correct dehydration, acidosis and electrolyte abnormalities is the cornerstone of treatment for diabetic ketoacidosis (DKA) but little is known about optimal fluid infusion rates and electrolyte cont…
View article: Intracranial Traumatic Hematoma Detection in Children Using a Portable Near-infrared Spectroscopy Device
Intracranial Traumatic Hematoma Detection in Children Using a Portable Near-infrared Spectroscopy Device Open
The handheld brain scanner can non-invasively detect a subset of intracranial hematomas in children and may serve an adjunctive role to head-injury neuroimaging decision rules that predict the risk of clinically significant intracranial pa…
View article: Longitudinal effect of high frequency training on CPR performance during simulated and actual pediatric cardiac arrest
Longitudinal effect of high frequency training on CPR performance during simulated and actual pediatric cardiac arrest Open
View article: Frequency and Risk Factors of Acute Kidney Injury During Diabetic Ketoacidosis in Children and Association With Neurocognitive Outcomes
Frequency and Risk Factors of Acute Kidney Injury During Diabetic Ketoacidosis in Children and Association With Neurocognitive Outcomes Open
These findings suggest that AKI may occur more frequently in children with greater acidosis and circulatory volume depletion during DKA and may be part of a pattern of multiple organ injury involving the kidneys and brain.
View article: 639. Short Course Therapy for Urinary Tract Infections (SCOUT) in Children
639. Short Course Therapy for Urinary Tract Infections (SCOUT) in Children Open
Background The AAP recommends 7 to 14-days of antimicrobials for the treatment of urinary tract infections (UTIs), one of the most common bacterial infections of childhood. However, most physicians routinely prescribe at least 10 days of t…
View article: Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1 Diabetes
Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1 Diabetes Open
Objective. This study assessed whether a single diabetic ketoacidosis (DKA) episode is associated with cognitive declines in children with newly diagnosed type 1 diabetes, and whether the same is true in children who had been previo…
View article: Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1 Diabetes
Cognitive Function following Diabetic Ketoacidosis in Children with New Onset or Previously Diagnosed Type 1 Diabetes Open
Objective. This study assessed whether a single diabetic ketoacidosis (DKA) episode is associated with cognitive declines in children with newly diagnosed type 1 diabetes, and whether the same is true in children who had been previo…
View article: Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes
Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes Open
OBJECTIVE This study assessed whether a single diabetic ketoacidosis (DKA) episode is associated with cognitive declines in children with newly diagnosed type 1 diabetes and whether the same is true in children who had previously been diag…
View article: Locations of Mass Shootings Relative to Schools and Places Frequented by Children
Locations of Mass Shootings Relative to Schools and Places Frequented by Children Open
This cohort study investigates the locations of mass shootings in relation to schools and places frequented by children.