Sahaya Glingston Rajakani
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View article: Characterization of genome-wide transpositions induced by colistin exposure in multi-drug-resistant <i>Klebsiella pneumoniae</i>
Characterization of genome-wide transpositions induced by colistin exposure in multi-drug-resistant <i>Klebsiella pneumoniae</i> Open
Colistin is one of the last-line antibiotics against multi-drug-resistant (MDR) gram-negative pathogens, such as Klebsiella pneumoniae . Using long-read sequencing, we observed remarkable genome-wide transposition events in MDR K. pneumoni…
View article: Assessment of Colistin Heteroresistance among Multidrug-Resistant Klebsiella pneumoniae Isolated from Intensive Care Patients in Europe
Assessment of Colistin Heteroresistance among Multidrug-Resistant Klebsiella pneumoniae Isolated from Intensive Care Patients in Europe Open
Heteroresistance (HR) to colistin is especially concerning in settings where multi-drug-resistant (MDR) K. pneumoniae are prevalent and empiric use of colistin might lead to treatment failures. This study aimed to assess the frequency of o…
View article: Assessment of colistin heteroresistance among multidrug-resistant Klebsiella pneumoniae isolated from intensive care patients in Europe
Assessment of colistin heteroresistance among multidrug-resistant Klebsiella pneumoniae isolated from intensive care patients in Europe Open
Heteroresistance (HR) to colistin is especially concerning in settings where multi-drug resistant (MDR) K. pneumoniae are prevalent and empiric use of colistin might lead to treatment failures. This study aimed to assess the frequency of o…
View article: Insight into Antibiotic Synergy Combinations for Eliminating Colistin Heteroresistant Klebsiella pneumoniae
Insight into Antibiotic Synergy Combinations for Eliminating Colistin Heteroresistant Klebsiella pneumoniae Open
Colistin heteroresistance has been identified in several bacterial species, including Escherichia coli and Klebsiella pneumoniae, and may underlie antibiotic therapy failures since it most often goes undetected by conventional antimicrobia…
View article: Screening of global microbiomes implies ecological boundaries impacting the distribution and dissemination of clinically relevant antimicrobial resistance genes
Screening of global microbiomes implies ecological boundaries impacting the distribution and dissemination of clinically relevant antimicrobial resistance genes Open
View article: Diversity in the Characteristics of Klebsiella pneumoniae ST101 of Human, Environmental, and Animal Origin
Diversity in the Characteristics of Klebsiella pneumoniae ST101 of Human, Environmental, and Animal Origin Open
Background Klebsiella pneumoniae ST101 is an emerging high-risk clone which exhibits extensive drug resistance. Bacterial strains residing in multiple hosts show unique signatures related to host adaptation. In this study, we assess the ge…
View article: Novel vancomycin resistance gene cluster in Enterococcus faecium ST1486, Belgium, June 2021
Novel vancomycin resistance gene cluster in Enterococcus faecium ST1486, Belgium, June 2021 Open
We identified a novel van gene cluster in a clinical Enterococcus faecium isolate with vancomycin minimum inhibitory concentration (MIC) of 4 µg/mL. The ligase gene, vanP , was part of a van operon cluster of 4,589 bp on a putative novel i…