Saheli Samanta
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View article: Suite of Biochemical and Cell-Based Assays for the Characterization of Kirsten Rat Sarcoma (KRAS) Inhibitors and Degraders
Suite of Biochemical and Cell-Based Assays for the Characterization of Kirsten Rat Sarcoma (KRAS) Inhibitors and Degraders Open
KRAS is an important oncogenic driver which is mutated in numerous cancers. Recent advances in the selective targeting of KRAS mutants via small molecule inhibitors and targeted protein degraders have generated an increase in research acti…
View article: Imprinting electrically switchable scalar spin chirality by anisotropic strain in a Kagome antiferromagnet
Imprinting electrically switchable scalar spin chirality by anisotropic strain in a Kagome antiferromagnet Open
Topological chiral antiferromagnets, such as Mn$_{3}$Sn, are emerging as promising materials for next-generation spintronic devices due to their intrinsic transport properties linked to exotic magnetic configurations. Here, we demonstrate …
View article: Effect of Heat Treatment on Coupled Magnetostructural Transition and Magnetocaloric Effect of Mnnige System
Effect of Heat Treatment on Coupled Magnetostructural Transition and Magnetocaloric Effect of Mnnige System Open
View article: Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity
Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity Open
View article: Exosomes: new molecular targets of diseases
Exosomes: new molecular targets of diseases Open
View article: Nanodiamond-based injectable hydrogel for sustained growth factor release: Preparation, characterization and in vitro analysis
Nanodiamond-based injectable hydrogel for sustained growth factor release: Preparation, characterization and in vitro analysis Open
View article: Epigenetic dysfunctional diseases and therapy for infection and inflammation
Epigenetic dysfunctional diseases and therapy for infection and inflammation Open
View article: Macrophage polarization in response to epigenetic modifiers during infection and inflammation
Macrophage polarization in response to epigenetic modifiers during infection and inflammation Open
View article: MicroRNA: A new therapeutic strategy for cardiovascular diseases
MicroRNA: A new therapeutic strategy for cardiovascular diseases Open
View article: Generation of Functional Cardiomyocytes from Efficiently Generated Human iPSCs and a Novel Method of Measuring Contractility
Generation of Functional Cardiomyocytes from Efficiently Generated Human iPSCs and a Novel Method of Measuring Contractility Open
Human induced pluripotent stem cells (iPSCs) derived cardiomyocytes (iCMCs) would provide an unlimited cell source for regenerative medicine and drug discoveries. The objective of our study is to generate functional cardiomyocytes from hum…
View article: Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury
Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury Open
Acute lung injury (ALI) during sepsis is characterized by bilateral alveolar infiltrates, lung edema, and respiratory failure. Here, we examined the efficacy of DNA methyl transferase (DNMT) inhibitor Aza (5-Aza 2-deoxycytidine), histone d…