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View article: <i>Withdrawn:</i> CircTDRD3 aggravates H/R‐induced cardiomyocyte apoptosis via targeting miR‐4295/TP63 axis
<i>Withdrawn:</i> CircTDRD3 aggravates H/R‐induced cardiomyocyte apoptosis via targeting miR‐4295/TP63 axis Open
The above article, published online on 5 December 2022, on Wiley Online Library ( https://doi.org/10.1002/jbt.23003 ), has been withdrawn by agreement between the journal Editor in Chief, Hari Bhat, and Wiley Periodicals, LLC. The withdraw…
View article: Tricking Enzymes In Living Cells: A Mechanism-Based Strategy For Design of DNA Topoisomerase Biosensors
Tricking Enzymes In Living Cells: A Mechanism-Based Strategy For Design of DNA Topoisomerase Biosensors Open
Most activity-based molecular probes are designed to target enzymes that catalyze the breaking of chemical bonds and the conversion of a unimolecular substrate into bimolecular products. However, DNA topoisomerases are a class of enzymes t…
View article: Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems
Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems Open
Flap structure-specific endonuclease 1 (FEN1) is overexpressed in various types of human cancer cells and has been recognized as a promising biomarker for cancer diagnosis in the recent years. In order to specifically detect the abundance …
View article: Study on catalytic properties of flap structure : specific endonuclease 1 and establishment of new platforms for screening its inhibitors
Study on catalytic properties of flap structure : specific endonuclease 1 and establishment of new platforms for screening its inhibitors Open
Flap structure-specific endonuclease 1 (FEN 1) is known to be essential for
\nreproduction and development of eukaryotic cells. During DNA replication in
\ncell division, a 5' flap structure is generated by polymerase 8. FENl
\nsubsequentl…