Explanipedia

P-81. A Decade of Culture-Negative Native Vertebral Osteomyelitis: Insights from the Mayo Clinic Open

Rita Igwilo-Alaneme, Said El Zein, Ryan B. Khodadadi, Francesco Petri, Omar Mahmoud , et al. · 2025

Background Culture-negative native vertebral osteomyelitis (CN-NVO) is increasingly common, rising from 0.3 to 1.8 cases per 100,000 between 1995 and 2008. The lack of microbial identification complicates optimal treatment and creates prog…

1283. Native Wrist Septic Arthritis: a 10-year Single Center Experience Open

Pansachee Damronglerd, Ryan B. Khodadadi, Said El Zein, Jack McHugh, Gina A. Suh , et al. · 2023

Background Native joint septic arthritis (NJSA) of the wrist is a rare condition, with published literature suggesting an incidence of approximately 1.5% among patients presenting with acute painful and swollen wrist. The aim of this study…

1287. Assessing the Utility of Vertebral Body / Disc Space Fluid Cell Differential in the Diagnosis of Native Vertebral Osteomyelitis Open

Said El Zein, Madeline J Kingsbury, Brian D. Lahr, Carrie M. Carr, Felix E. Diehn , et al. · 2023

Background Current approaches to diagnosing suspected native vertebral osteomyelitis (NVO) rely on imaging and microbiological workup, including blood and CT-guided biopsy cultures. These existing diagnostic methods often result in ambigui…

Rifampin Based Therapy for Patients With <i>Staphylococcus aureus</i> Native Vertebral Osteomyelitis: A Systematic Review and Meta-analysis Open

Said El Zein, Elie F. Berbari, Matteo Passerini, Francesco Petri, Julian Maamari , et al. · 2023

Background Native vertebral osteomyelitis (NVO) caused by Staphylococcus aureus is associated with high risk of treatment failure and increased morbidity. The role of rifampin-based therapy for the treatment of this condition is controvers…

Species designation of streptococci causing infective endocarditis in patients with mitral valve prolapse Open

Juan Andres Quintero-Martinez, Joya-Rita Hindy, Said El Zein, Holenarasipur R. Vikram, Wendelyn Bosch , et al. · 2023

The S. mitis group was the predominant species in our investigation. Continued evaluation of VGS species should be considered to profile the IE risk based on species identification.

Native joint polyarticular septic arthritis secondary to disseminated Ureaplasma urealyticum infection in a patient on rituximab therapy with hypogammaglobulinemia: A Case Report Open

Said El Zein, Thomas D. Garvey, Shreyasee Amin, Aaron J. Tande · 2023

Ureaplasma urealyticum and Ureaplasma parvum are important causes of septic arthritis in patients with hypogammaglobulinemia. The diagnosis can be challenging, leading to prolonged illness and increased morbidity, and mortali…

A Review of Hemophagocytic Lymphohistiocytosis in Patients With HIV Open

Hussam Tabaja, Amjad Kanj, Said El Zein, Işın Y. Comba, Omar Chehab , et al. · 2022

We provide an elaborate review of cases published between January 2005 and April 2021 on hemophagocytic lymphohistiocytosis (HLH) in HIV patients. Seventy articles describing 81 adult patients (age ≥19 years) were included. The median age …

SARS-CoV-2 infection: Initial viral load (iVL) predicts severity of illness/outcome, and declining trend of iVL in hospitalized patients corresponds with slowing of the pandemic Open

Said El Zein, Omar Chehab, Amjad Kanj, Sandy Akrawe, Samer Alkassis , et al. · 2021

Background Hospitalization of patients infected with the severe acute respiratory syndrome virus 2 (SARS-CoV-2) have remained considerable worldwide. Patients often develop severe complications and have high mortality rates. The cycle thre…

SARS-CoV-2 Viral Load and Myocardial Injury: Independent and Incremental Predictors of Adverse Outcome Open

Omar Chehab, Said El Zein, Amjad Kanj, Adel Moghrabi, Joseph Sebastian , et al. · 2021

SARS-COV-2 VIRAL LOAD AND CARDIAC INJURY ARE INDEPENDENT AND INCREMENTAL PREDICTORS OF IN-HOSPITAL MORTALITY Open

Omar Chehab, Said El Zein, Adel Elmoghrabi, Joseph Sebastian, Tyler Mumm , et al. · 2021

COVID PLOS DATA.xlsx Open

Said El Zein · 2021

Cycle threshold values of COVID PCR. Project reviewed and approved by Wayne State / DMC IRB

COVID PLOS DATA.xlsx Open

Said El Zein · 2021

Cycle threshold values of COVID PCR. Project reviewed and approved by Wayne State / DMC IRB

COVID PLOS DATA.xlsx Open

Said El Zein · 2021

Cycle threshold values of COVID PCR. Project reviewed and approved by Wayne State / DMC IRB

The Prevalence of Co-Infections in Hospitalized Patients with COVID-19 Open

Siri S. Sarvepalli, Said El Zein, Pranatharthi Chandrasekar · 2021

Introduction: The Coronavirus disease 2019 (COVID-19) pandemic emerged in early 2020 and significantly altered the landscape of healthcare delivery. With the absence of a cure, treatment of hospitalized patients with COVID-19 has been part…

Declining Trend in the Initial SARS-CoV-2 Viral Load During the Pandemic: Preliminary Observations from Detroit, Michigan Open

Said El Zein, Nivine El-Hor, Omar Chehab, Samer Alkassis, Tushar Mishra , et al. · 2020

We report a downward trend in the initial SARS-CoV-2 viral load in nasopharyngeal swab samples of hospitalized patients with COVID-19 in Detroit, Michigan, coinciding with a decrease in the number of deaths during April-June 2020. A gradua…

Invasive Saprochaete Infections: An Emerging Threat to Immunocompromised Patients Open

Said El Zein, Joya-Rita Hindy, Souha S. Kanj · 2020

Saprochaete clavata and Saprochaete capitata are emerging fungal pathogens that are responsible for life threatening infections in immunocompromised patients, particularly in the setting of profound neutropenia. They have been associated w…

Prevalence of infections and antimicrobial use in the acute-care hospital setting in the Middle East: Results from the first point-prevalence survey in the region Open

Adel Alothman, Abdulhakeem Al Thaqafi, Adel Al Ansary, Ahmed Zikri, Akram Muhammad Fayed , et al. · 2020

Alopecia After Switch to Tenofovir Alafenamide in 6 African American Women Open

Said El Zein, Hussam Tabaja, Amjad Kanj, Deborah Richmond, Jennifer Veltman · 2019

No cases of tenofovir alafenamide (TAF)–induced alopecia have been reported in the literature. We describe 6 cases of hair loss in African American female patients after switching to TAF and aim to raise awareness about this potential adve…

Visceral and Cutaneous Leishmaniases in a City in Syria and the Effects of the Syrian Conflict Open

Alexey Youssef, Rim Harfouch, Said El Zein, Zuheir Alshehabi, Rafea Shaaban , et al. · 2019

War provides ideal grounds for the outbreak of infectious diseases, and the Syrian war is not an exception to this rule. Following the civil crisis, Syria and refugee camps of neighboring countries witnessed an outbreak of leishmaniasis. W…

Unusual presentation of primary lung adenocarcinoma mimicking pneumonia: Case report and literature review Open

Asil Daoud, Amir Laktineh, Said El Zein, Ayman O. Soubani · 2019

Primary lung adenocarcinoma, diffuse pneumonic type, can mimic the clinical presentation of an infectious or inflammatory lung disease, which can represent a diagnostic challenge. We present an unusual case of adenocarcinoma of the lung re…

Non-O1, non-O139 Vibrio cholerae bacteremia in an urban academic medical center in the United States Open

John Shanley, Amjad Kanj, Said El Zein, Hussam Tabaja, Brett Trzcinski , et al. · 2019

Non-O1, non-O139 Vibrio cholerae (NOVC) are genetically diverse strains that are generally non-pathogenic in healthy hosts. In immunocompromised patients or those with liver disease, NOVC have been shown to cause gastroenteritis, wo…

Migrating gossypiboma mimicking aspergilloma twenty years after mediastinal surgery Open

Amjad Kanj, Ayman O. Soubani, Hussam Tabaja, Said El Zein, Mirna Fares , et al. · 2018

A gossypiboma refers to a surgical sponge or gauze accidentally retained inside a patient during a procedure. It is more commonly encountered after abdominal surgeries. When seen in the thorax, it is usually located within the pleural cavi…

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