Saïda Abounit
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View article: Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine
Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine Open
The disrupted-in-schizophrenia 1 ( DISC1 ) gene was identified as a genetic risk factor for chronic mental illnesses (CMI) such as schizophrenia, bipolar disorder and severe recurrent depression. Insoluble aggregated DISC1 variants were fo…
View article: Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases
Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases Open
The mechanisms of intercellular spreading of amyloidogenic proteins involved in neurodegenerative diseases have yet to be fully elucidated. While secretion has been implicated in the transfer of many proteins, including prions and α-synucl…
View article: Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes
Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes Open