Saif Badran
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View article: Evaluating SnapshotNIR for Tissue Oxygenation Measurement Across Skin Types After Mastectomy
Evaluating SnapshotNIR for Tissue Oxygenation Measurement Across Skin Types After Mastectomy Open
Accurate monitoring of mastectomy skin flap (MSF) perfusion is critical, especially in patients with darker skin pigmentation at higher risk of misdiagnosed tissue ischemia. Near-infrared spectroscopy (NIRS) devices, such as SnapshotNIR, o…
View article: Efficacy of closed-incision negative pressure wound therapy in abdominal-based autologous breast reconstruction: A systematic review and meta-analysis
Efficacy of closed-incision negative pressure wound therapy in abdominal-based autologous breast reconstruction: A systematic review and meta-analysis Open
ciNPWT demonstrates a significant reduction in wound dehiscence, highlighting its value in enhancing postoperative care, especially for high-risk patients. However, further research involving larger, multicenter randomized controlled trial…
View article: Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft
Soft Tissue Stabilization of Midcarpal Instability in Ehlers–Danlos Patients Using a Cadaveric Tendon Graft Open
Summary: Ehlers–Danlos syndrome (EDS) is a group of hereditary disorders that affects collagen synthesis. In the wrist, pain and midcarpal laxity may affect up to 70% of EDS patients. The mainstay treatment of midcarpal instability in pati…
View article: Autologous breast reconstruction in patients with primary hypercoagulability disorders
Autologous breast reconstruction in patients with primary hypercoagulability disorders Open
The rising demand for autologous breast reconstruction presents challenges for patients with primary hypercoagulability disorders due to their elevated thrombotic risks. In this article, we reviewed 13 patients who underwent 23 free flap b…
View article: Hormonal predictors of the insulin sensitive phenotype in humans
Hormonal predictors of the insulin sensitive phenotype in humans Open
Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and a heightened risk of comorbidities. This study aimed to identify hormonal predictors of an insulin-sensitive phenotype (ISP) …
View article: Hormonal predictors of the lean phenotype in humans
Hormonal predictors of the lean phenotype in humans Open
Clinical obesity is characterized by excessive fat accumulation and an increased risk of numerous associated comorbidities. Adipose tissue secretes leptin and other adipokines, which play key roles in regulating energy balance, glucose hom…
View article: The Utility of Indocyanine Green Angiography in Breast Reconstruction to Detect Mastectomy Skin Flap Necrosis and Free Flap Perfusion: An Umbrella Review
The Utility of Indocyanine Green Angiography in Breast Reconstruction to Detect Mastectomy Skin Flap Necrosis and Free Flap Perfusion: An Umbrella Review Open
Two of the greatest challenges in breast reconstruction are mastectomy skin flap necrosis (MSFN) and autologous flap failure. This review summarizes current evidence regarding the usage of indocyanine green angiography (ICGA) in breast rec…
View article: The Impact of Prior Obesity Surgery on Bleeding after Abdominal Body Contouring Surgery
The Impact of Prior Obesity Surgery on Bleeding after Abdominal Body Contouring Surgery Open
Background: Body contouring surgery removes excess skin and fat, often after massive weight loss. Some reports suggest that patients who have previously undergone obesity (bariatric) surgery are at excess risk of subsequent bleeding, possi…
View article: Validation of a Risk Prediction Model for COVID-19: The PERIL Prospective Cohort Study
Validation of a Risk Prediction Model for COVID-19: The PERIL Prospective Cohort Study Open
Aim: This study aims to perform an external validation of a recently developed prognostic model for early prediction of the risk of progression to severe COVID-19. Patients & methods/materials: Patients were recruited at their initial diag…
View article: The impact of prior obesity surgery on glucose metabolism after body contouring surgery: A pilot study
The impact of prior obesity surgery on glucose metabolism after body contouring surgery: A pilot study Open
Body contouring surgery enhances physical appearance by means of surgical subcutaneous fat removal (SSFR). However, it remains unclear how SSFR may affect glucose metabolism and its broader effects on the endocrine system, especially in in…
View article: Validation of Doi’s weighted average glucose as a measure of post-load glucose excursion for clinical use
Validation of Doi’s weighted average glucose as a measure of post-load glucose excursion for clinical use Open
In this study, we examined the performance of a novel index of glucose excursion (Doi’s weighted average glucose [dwAG]) in relation to the conventional measure of area under the oral glucose tolerance test (A-GTT) and the homeostatic mode…
View article: Metabolic aspects of surgical subcutaneous fat removal: An umbrella review and implications for future research
Metabolic aspects of surgical subcutaneous fat removal: An umbrella review and implications for future research Open
Although obesity is a preventable disease, maintaining a normal body weight can be very challenging and difficult, which has led to a significant increase in the demand for surgical subcutaneous fat removal (SSFR) to improve physical appea…
View article: Date Palm Thorn Injury: A Literature Review and a Case Study of Extensive Hand Haematoma
Date Palm Thorn Injury: A Literature Review and a Case Study of Extensive Hand Haematoma Open
Date palm thorn injuries require a high level of clinical suspicion and careful management as they can lead to severe complications, such as tissue inflammation, synovitis, and extensive haematoma. Although it is associated with serious in…
View article: Development and Validation of an Early Scoring System for Prediction of Disease Severity in COVID-19 Using Complete Blood Count Parameters
Development and Validation of an Early Scoring System for Prediction of Disease Severity in COVID-19 Using Complete Blood Count Parameters Open
The coronavirus disease 2019 (COVID-19) after outbreaking in Wuhan increasingly spread throughout the world. Fast, reliable, and easily accessible clinical assessment of the severity of the disease can help in allocating and prioritizing r…
View article: An Evidence Base for School Health Policy during the COVID-19 Pandemic
An Evidence Base for School Health Policy during the COVID-19 Pandemic Open
Objective: Children represent a small fraction of confirmed COVID-19 cases, with a low case fatality rate (CFR). In this paper, we lay out an evidence-based policy for reopening schools. Methods: We gathered age-specific COVID-19 case coun…
View article: Efficacy of chloroquine and hydroxychloroquine in treating COVID-19 infection: a meta-review of systematic reviews and an updated meta-analysis
Efficacy of chloroquine and hydroxychloroquine in treating COVID-19 infection: a meta-review of systematic reviews and an updated meta-analysis Open
Objective To synthesize findings from systematic reviews and meta-analyses on the efficacy and safety of chloroquine (CQ) and hydroxychloroquine (HCQ) with or without Azithromycin for treating COVID-19, and to update the evidence using a m…
View article: Recurrent Desmoid Tumor with Intra-Abdominal Extension After Abdominoplasty: A Rare Presentation
Recurrent Desmoid Tumor with Intra-Abdominal Extension After Abdominoplasty: A Rare Presentation Open
BACKGROUND Desmoid tumors are fibrous neoplasms that originate from the musculoaponeurotic structures in the body. Abdominal wall desmoid tumors are rare, but they can be locally aggressive, with high incidence of recurrence. These tumors …
View article: A Rare Presentation of Axial Chordoma and the Approach to Management
A Rare Presentation of Axial Chordoma and the Approach to Management Open
BACKGROUND Chordoma is a primary bone tumor that most commonly arises in the sacrococcygeal vertebrae and the spheno-occipital areas. Chordoma is a malignant tumor that should be distinguished from benign notochordal cell tumor (BNCT) of t…