Saifullah Afridi
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View article: Dual-Action Compounds for Glycemic Control: N-Benzyl-2,5-Dioxopyrrolidin-3-yl-Methanesulfonamide and 2-Benzylsuccinimide mimic α-Amylase and α-Glucosidase activities to regulate blood glucose levels
Dual-Action Compounds for Glycemic Control: N-Benzyl-2,5-Dioxopyrrolidin-3-yl-Methanesulfonamide and 2-Benzylsuccinimide mimic α-Amylase and α-Glucosidase activities to regulate blood glucose levels Open
Diabetes mellitus is one of the most alarming metabolic syndromes caused by high blood sugar levels. Herein, we report the identification of two potent antidiabetic agents: N-benzyl-2,5-dioxopyrrolidin-3-yl-methanesulfonamide (NDMS) and 2-…
View article: Design of Water‐Soluble PEGylated Heptapeptide‐Based Multifunctional Magnetic Nanovesicles for Cancer Targeted MRI Integrated With Fluorescence Imaging
Design of Water‐Soluble PEGylated Heptapeptide‐Based Multifunctional Magnetic Nanovesicles for Cancer Targeted MRI Integrated With Fluorescence Imaging Open
Integrating fluorescent dyes with magnetic resonance imaging (MRI) agents to extract synergistic imaging details is imperative. A de novo designed PEGylated heptapeptide/aggregation‐induced emission (AIE) dye and MRI probe‐conjugated multi…
View article: Nanozyme-based sensing of dopamine using cobalt-doped hydroxyapatite nanocomposite from waste bones
Nanozyme-based sensing of dopamine using cobalt-doped hydroxyapatite nanocomposite from waste bones Open
Dopamine is one of the most important neurotransmitters and plays a crucial role in various neurological, renal, and cardiovascular systems. However, the abnormal levels of dopamine mainly point to Parkinson’s, Alzheimer’s, cardiovascular …
View article: Colorimetric sensing of hydrogen peroxide using capped Morus nigra-sawdust deposited zinc oxide nanoparticles via Trigonella foenum extract
Colorimetric sensing of hydrogen peroxide using capped Morus nigra-sawdust deposited zinc oxide nanoparticles via Trigonella foenum extract Open
Hydrogen peroxide (H 2 O 2 ) is one of the main byproducts of most enzymatic reactions, and its detection is very important in disease conditions. Due to its essential role in healthcare, the food industry, and environmental research, accu…
View article: Colorimetric sensing of uric acid based on sawdust-deposited silver nanoparticles via an eco-friendly and cost-effective approach
Colorimetric sensing of uric acid based on sawdust-deposited silver nanoparticles via an eco-friendly and cost-effective approach Open
Uric acid is directly linked to gout, arthritis, neurological, cardiovascular, and kidney-related disorders. It is a byproduct obtained from the breakdown of purines and a significant indicator of hyperuricemia observed in both urine and b…
View article: Paracetamol-Mediated Synthesis of Silver Nanoparticles and Their Functionalization with Ionic Liquid for the Colorimetric Biosensing of Ascorbic Acid
Paracetamol-Mediated Synthesis of Silver Nanoparticles and Their Functionalization with Ionic Liquid for the Colorimetric Biosensing of Ascorbic Acid Open
Ascorbic acid is a vital biomolecule for human beings. When the body's level of ascorbic acid is abnormal, it can lead to a number of illnesses. Its appropriate concentration is necessary for the oxidation of prostaglandins and cyclic aden…
View article: Fabrication of a colorimetric sensor using acetic acid-capped drug-mediated copper oxide nanoparticles for nitrite biosensing in processed food
Fabrication of a colorimetric sensor using acetic acid-capped drug-mediated copper oxide nanoparticles for nitrite biosensing in processed food Open
Nitrite (NO 2 − ) and nitrate (NO 3 − ) are frequently used in cured meat products as preservatives, as they give a better taste and work well in color fixation. As a key possible carcinogen, excessive dietary consumption of NO 2 − in cure…
View article: Development of a Nonenzymatic Colorimetric Sensor for the Detection of Uric Acid Based on Ionic Liquid-Mediated Nickel Nanostructures
Development of a Nonenzymatic Colorimetric Sensor for the Detection of Uric Acid Based on Ionic Liquid-Mediated Nickel Nanostructures Open
Uric acid (UA) is a metabolic byproduct of purine nucleotides and is excreted as a urine component. Abnormalities in UA metabolism cause localized inflammation due to crystal deposition and can lead to various diseases. In the current stud…
View article: Diagenetic Modifications and Reservoir Heterogeneity Associated with Magmatic Intrusions in the Devonian Khyber Limestone, Peshawar Basin, NW Pakistan
Diagenetic Modifications and Reservoir Heterogeneity Associated with Magmatic Intrusions in the Devonian Khyber Limestone, Peshawar Basin, NW Pakistan Open
In the present study, an attempt has been made to establish the relationship between diagenetic alterations resulting from magmatic intrusions and their impact on the reservoir properties of the Devonian Khyber Limestone (NW Pakistan). Fie…
View article: Pakistani youth population is prone to SARS-CoV-2 (nCoVID-19) Infection
Pakistani youth population is prone to SARS-CoV-2 (nCoVID-19) Infection Open
The novel coronavirus (nCOVID-19) with potential for human-to-human transmission at an exponential rate across the globe has been shown in numerous reports. According to WHO declaration COVID-19 is a global emergency with over 40 million i…
View article: Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression
Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression Open
View article: MOLECULAR CHARACTERIZATION AND PRODUCTION OF BACTERIAL AMYLASES FROM SHAHDARA SPRING, PAKISTAN
MOLECULAR CHARACTERIZATION AND PRODUCTION OF BACTERIAL AMYLASES FROM SHAHDARA SPRING, PAKISTAN Open
Microorganisms are the preferred source of enzyme applicable to a variety of industries, such as food, paper, detergent, and energy.In this study, amylase enzymes were explored for the first time in the springs of Shahdara, Islamabad, Paki…
View article: Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors
Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors Open
View article: Introductory Chapter: Ion Channels
Introductory Chapter: Ion Channels Open
View article: A comparative toxic effect of Cedrus deodara oil on larval protein contents and its behavioral effect on larvae of mealworm beetle (Tenebrio molitor) (Coleoptera: Tenebrionidae)
A comparative toxic effect of Cedrus deodara oil on larval protein contents and its behavioral effect on larvae of mealworm beetle (Tenebrio molitor) (Coleoptera: Tenebrionidae) Open
View article: Individual immune system responds differently.
Individual immune system responds differently. Open
Each individual immune system is highly specific but extremely distant from other individuals.Based on recent technological advancement whole immune system analysis reveal different immune profiling for every individual.Herein, we clarifie…
View article: CCDC 1017216: Experimental Crystal Structure Determination
CCDC 1017216: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …