Saima Khaliq
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View article: Acipimox mitigates depression like behavior following high fat rich diet in rats
Acipimox mitigates depression like behavior following high fat rich diet in rats Open
Acipimox (ACPX), a niacin derivative, has demonstrated antioxidant activity In vitro and In vivo; however, it has not been widely used in treating neurological problems. The present study examined the effects of Acipimox on body weight, di…
View article: Gallic acid alleviates omeprazole-induced depressive behavior and memory impairment
Gallic acid alleviates omeprazole-induced depressive behavior and memory impairment Open
View article: Antidepressive and anxiolytic effects of a combination of Saffron and Chamomile in rats and their relationship with serotonin using methods.
Antidepressive and anxiolytic effects of a combination of Saffron and Chamomile in rats and their relationship with serotonin using methods. Open
This study shows that in comparison to treatment with a SSRI, and individual herbs, the combination of chamomile and saffron showed overall improved outcomes.
View article: Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment
Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment Open
Aging is an invincible phenomenon that is a risk factor for the development of neurological disorders such as anxiety, depression, and memory decline that are prominent in aging. The present study aims to evaluate the effect of Niacin (Nn)…
View article: Protective effects of niacin following high fat rich diet: an in-vivo and in-silico study
Protective effects of niacin following high fat rich diet: an in-vivo and in-silico study Open
Niacin had long been understood as an antioxidant. There were reports that high fat diet (HFD) may cause psychological and physical impairments. The present study was aimed to experience the effect of Niacin on % growth rate, cumulative fo…
View article: Interactions of Apigenin and Safranal with the 5HT1A and 5HT2A Receptors and Behavioral Effects in Depression and Anxiety: A Molecular Docking, Lipid-Mediated Molecular Dynamics, and In Vivo Analysis
Interactions of Apigenin and Safranal with the 5HT1A and 5HT2A Receptors and Behavioral Effects in Depression and Anxiety: A Molecular Docking, Lipid-Mediated Molecular Dynamics, and In Vivo Analysis Open
Background: The current study utilizes in silico molecular docking/molecular dynamics to evaluate the binding affinity of apigenin and safranal with 5HT1AR/5HT2AR, followed by assessment of in vivo effects of these compounds on depressive …
View article: Ameliorative effects of half-dose saffron and chamomile combination on Psycho-endocrinological changes in a diabetic murine model
Ameliorative effects of half-dose saffron and chamomile combination on Psycho-endocrinological changes in a diabetic murine model Open
Introduction Diabetes mellitus is a chronic metabolic disorder with an increasing prevalence worldwide. Reduction in blood insulin level alters brain function by inducing oxidative stress with changes in dopamine and norepinephrine neurotr…
View article: Effect of guided reading strategies on the motivation of the students to increase reading skill of elementary level students in the subjects of English
Effect of guided reading strategies on the motivation of the students to increase reading skill of elementary level students in the subjects of English Open
The study investigated the Effect of guided reading strategies on the motivation of the students to increase reading skill of elementary level students in the subjects of English. The major objectives of the study were as follows: (i) to f…
View article: Biosynthesis of silver nanoparticles from Mukia maderaspatana (L) and their biological activities.
Biosynthesis of silver nanoparticles from Mukia maderaspatana (L) and their biological activities. Open
Nanotechnology is a field of science that consists of atoms, molecules and supramolecular molecules that create nanoparticles ranging in size from 1-100nm. Silver nanoparticles are widely used that are considered as effective antimicrobial…
View article: Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity.
Tryptophan lessens reserpine induced anxiety, depression and memory impairment by modulating oxidative stress and serotonergic activity. Open
Reserpine (Res)-induced depletion of monoamines and altered neurotransmission and produces oxidative stress. Tryptophan (TRP) regulated the serotonin neurotransmission. Because systemically injected Res induced behavioral deficits and oxid…
View article: Persea americana seeds improve glycosylation and dyslipidemia in fructose-fed streptozotocin-injected type 2 diabetic male rats.
Persea americana seeds improve glycosylation and dyslipidemia in fructose-fed streptozotocin-injected type 2 diabetic male rats. Open
This work explored the in-vitro phytochemical contents and antidiabetic activity of crude seeds powder of Persea americana (CSSPa) and their in-vivo biochemical effects on glycated hemoglobin, lipid profile and other parameters in type 2 d…
View article: Diet supplements of banana fruit pulp mitigates repeated noise stress induced behavioral deficits and oxidative stress.
Diet supplements of banana fruit pulp mitigates repeated noise stress induced behavioral deficits and oxidative stress. Open
The current study was designed to determine the outcome of banana fruit pulp (BFP) on repeated noise stress exposure (NSE)-induced behavioral deficits and oxidative stress in male mice. BFP (600mg/kg b.w) was administered orally once daily…
View article: Effect of lithium chloride on d-galactose induced organs injury: Possible antioxidative role.
Effect of lithium chloride on d-galactose induced organs injury: Possible antioxidative role. Open
The aging process is concerned with oxidative stress and causing malfunction of various organs such as the liver, kidney and heart. Lithium (Li) salts have shown anti-manic, anti-suicidal, and antioxidant properties. The current study is a…
View article: Spirulina platensis (Blue-green algae): A miracle from sea combats the oxidative stress and improves behavioral deficits in an animal model of Schizophrenia.
Spirulina platensis (Blue-green algae): A miracle from sea combats the oxidative stress and improves behavioral deficits in an animal model of Schizophrenia. Open
Spirulina platensis (blue-green algae) is a nutritional supplement. It constitutes of high content of protein, antioxidants, various phytopigments and possesses neuroprotective activities. Schizophrenia (SZ) is recognized as a neuropsychia…
View article: Effects of Feed Additives on Chicken Growth and Their Residues in Meat Instigating Deleterious Consequences on the Liver Health of Consumers - A Prospective Human Study
Effects of Feed Additives on Chicken Growth and Their Residues in Meat Instigating Deleterious Consequences on the Liver Health of Consumers - A Prospective Human Study Open
The liver is a multifunctional organ that metabolizes all forms of diets, and food ingredients can have beneficial or detrimental effects on liver cells during such a process. As we have already studied the components of chicken feed previ…
View article: Sargassum swartzii extracts ameliorate memory functions by neurochemical modulation in a rat model
Sargassum swartzii extracts ameliorate memory functions by neurochemical modulation in a rat model Open
View article: Antidepressant-like deliverables from the sea: evidence on the efficacy of three different brown seaweeds via involvement of monoaminergic system
Antidepressant-like deliverables from the sea: evidence on the efficacy of three different brown seaweeds via involvement of monoaminergic system Open
Brown seaweeds exhibit several health benefits in treating and managing wide array of ailments. In this study, the antidepressant-like effect of methaolic extracts from Sargassum swartzii (SS), Stoechospermum marginatum (SM), and Nizamuddi…
View article: Public health relevance of non-tuberculous mycobacteria among AFB positive sputa
Public health relevance of non-tuberculous mycobacteria among AFB positive sputa Open
NTM were present in at least 1.3% of all smear positive samples. It is important for public health programs to recognize the avoidable burden on logistics, infrastructure and finances caused by this. Detection and quantification of this bu…
View article: An Experimental Study to Investigate the Effectiveness of Project-Based Learning (PBL) for Teaching Science at Elementary Level
An Experimental Study to Investigate the Effectiveness of Project-Based Learning (PBL) for Teaching Science at Elementary Level Open
Information and communication technology (ICT) covers different types enabling use to receive, share and exchange information. In project-based learning (PBL), the learners remained the center of the process by engaging, collaborating and …
View article: Antibacterial Bioassay Screening of 2'-o-Ethylmurrangatin: A Secondary Metabolite Obtained from Murraya paniculata
Antibacterial Bioassay Screening of 2'-o-Ethylmurrangatin: A Secondary Metabolite Obtained from Murraya paniculata Open