Sajjad Ahmed Khan
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View article: Extramedullary plasmacytoma in the subglottic region: A rare cause of dyspnea and hoarseness – a case report
Extramedullary plasmacytoma in the subglottic region: A rare cause of dyspnea and hoarseness – a case report Open
Rationale: Extramedullary plasmacytomas (EMPs) are a variant of plasma cell disorders, commonly involving the upper respiratory tract. This case describes a rare occurrence of EMP in the subglottic region of the larynx presenting with dysp…
View article: Submental intubation in maxillofacial trauma: A comprehensive review of techniques, outcomes, and clinical applications
Submental intubation in maxillofacial trauma: A comprehensive review of techniques, outcomes, and clinical applications Open
Securing a definitive airway in maxillofacial trauma is paramount yet challenging due to anatomical disruption, hemorrhage, and trismus. Conventional orotracheal or nasotracheal intubation can be contraindicated or hazardous. Submental int…
View article: Coping strategies and mental health among remote hospital workers in the COVID-19 pandemic: A multicenteric cohort study from Pakistan
Coping strategies and mental health among remote hospital workers in the COVID-19 pandemic: A multicenteric cohort study from Pakistan Open
The COVID-19 pandemic and digital transformations have led to a significant expansion of remote work in healthcare settings. This longitudinal, multicenter study evaluated personal and organizational coping strategies employed by remote ho…
View article: Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank
Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank Open
In recent years, coinciding with the increasing incidence of type 2 diabetes mellitus (T2DM) in children and adolescents, the global prevalence of diabetic kidney disease (DKD) and end-stage renal disease (ESRD) are rising year on year. In…
View article: Knowledge, Attitude and Practice on Oral Health among Patients Visiting Dental Center: A Cross-Sectional Study
Knowledge, Attitude and Practice on Oral Health among Patients Visiting Dental Center: A Cross-Sectional Study Open
Introduction: Oral health is a vital component of overall health and quality of life. Poor knowledge, negative attitudes, and inadequate practices regarding oral hygiene contribute significantly to the global burden of dental diseases, esp…
View article: Impact of abnormal amniotic fluid index on maternal and perinatal outcomes in term pregnancies
Impact of abnormal amniotic fluid index on maternal and perinatal outcomes in term pregnancies Open
Amniotic fluid, the protective medium within the amniotic sac, plays a vital role in fetal development and maternal well-being during pregnancy. Abnormal amniotic fluid index (AFI), including oligohydramnios (AFI ≤ 2 cm) and polyhydramnios…
View article: Exploring the prevalence and determinants of acute kidney injury in neonatal ICU patients: Insights from a low-middle income country
Exploring the prevalence and determinants of acute kidney injury in neonatal ICU patients: Insights from a low-middle income country Open
Neonatal acute kidney injury (AKI) represents a serious clinical concern, especially in intensive care settings where early organ dysfunction can significantly affect short-term recovery and long-term outcomes. This study investigated the …
View article: Determinants of poststroke depression and its impact on functional outcomes: A hospital-based study in Nepal
Determinants of poststroke depression and its impact on functional outcomes: A hospital-based study in Nepal Open
Poststroke depression (PSD) is a common yet underrecognized neuropsychiatric condition that significantly affects the functional and psychosocial outcomes of stroke survivors. The etiology of PSD is complex and influenced by a combination …
View article: Diagnosing and Managing Pelizaeus‐Merzbacher Disease: A Pediatric Struggle
Diagnosing and Managing Pelizaeus‐Merzbacher Disease: A Pediatric Struggle Open
Prompt diagnosis of rare genetic conditions like Pelizaeus‐Merzbacher Disease enables timely care. Coordinated, multidisciplinary support and proactive prevention, particularly of issues like aspiration pneumonia, are vital to enhancing qu…
View article: Sirenomelia and the Spectrum of Caudal Anomalies: Clinical Reflections From a Preterm Termination
Sirenomelia and the Spectrum of Caudal Anomalies: Clinical Reflections From a Preterm Termination Open
Severe oligohydramnios with fetal anomalies, like sirenomelia, requires early diagnosis to prevent maternal complications such as infection or hemorrhage from delayed detection. Challenges in resource‐limited settings hinder timely interve…
View article: A dentigerous cyst with an ectopic tooth nestled in the maxillary sinus: A case report
A dentigerous cyst with an ectopic tooth nestled in the maxillary sinus: A case report Open
Rationale: Dentigerous cysts (DCs), often referred to as radicular cysts, are benign odontogenic lesions that primarily affect the roots of teeth. This case highlights the rare event of a DC associated with an ectopic tooth in maxillary si…
View article: Blueprints for Discovery: The Anatomy of a Global Medical Student Research Conference
Blueprints for Discovery: The Anatomy of a Global Medical Student Research Conference Open
Medical student research conferences are emerging as a critical platform to bridge the accessibility gap in early research training, foster collaboration, and enhance professional development. This editorial draws upon the experience of th…
View article: In vitro investigation of Datura innoxia phytocompounds against Mycobacterium tuberculosis H37Ra strain in association with in silico studies
In vitro investigation of Datura innoxia phytocompounds against Mycobacterium tuberculosis H37Ra strain in association with in silico studies Open
Tuberculosis (TB) is a recurrent and progressive bacterial disease caused by Mycobacterium tuberculosis ( Mtb ), posing a significant challenge globally due to its drug resistance. This study focuses on identifying natural phytocompounds f…
View article: Unveiling the Complexity: A Rare Case of Subarachnoid Hemorrhage Caused by a Ruptured Distal Anterior Communicating Artery Aneurysm and Its Surgical and Anesthetic Management
Unveiling the Complexity: A Rare Case of Subarachnoid Hemorrhage Caused by a Ruptured Distal Anterior Communicating Artery Aneurysm and Its Surgical and Anesthetic Management Open
Distal anterior communicating artery aneurysms require complex surgical exposure, often necessitating extensive dissection or frontal lobe manipulation, increasing neurological risks. When endovascular therapy is unfeasible, ruptured dista…
View article: Birth asphyxia in a resource-limited setting: Challenges and implications for neonatal care in Nepal
Birth asphyxia in a resource-limited setting: Challenges and implications for neonatal care in Nepal Open
Birth asphyxia is a common problem especially in low resource developing countries like Nepal during the delivery. Birth asphyxia remains a major cause of mortality and morbidity worldwide and specially in developing countries like Nepal. …
View article: Nasopharyngeal Carcinoma in a Pediatric Patient: Beyond the Norm
Nasopharyngeal Carcinoma in a Pediatric Patient: Beyond the Norm Open
View article: Temporal Bone Carcinoma Masquerading as Complicated Chronic Otitis Media
Temporal Bone Carcinoma Masquerading as Complicated Chronic Otitis Media Open
This case highlights the importance of early recognition of chronic ear discharge, facial nerve palsy, and swelling as potential indicators of aggressive conditions like squamous cell carcinoma. Future research should focus on improving ea…
View article: Achieving Effective Spinal Anesthesia in a Patient With Severe Spinal Deformities: Precision in Adversity
Achieving Effective Spinal Anesthesia in a Patient With Severe Spinal Deformities: Precision in Adversity Open
Spinal anesthesia is a safe and effective option for patients with severe spinal deformities, such as gibbus, ensuring positive outcomes for both mother and baby while avoiding general anesthesia. This highlights its feasibility even in co…
View article: Community-Based Cervical Cancer Screening Using VIA and Pap Smear in the Female Population of Eastern Nepal
Community-Based Cervical Cancer Screening Using VIA and Pap Smear in the Female Population of Eastern Nepal Open
View article: Correlation between umbilical cord blood pH with perinatal asphyxia and early neonatal outcome
Correlation between umbilical cord blood pH with perinatal asphyxia and early neonatal outcome Open
Perinatal asphyxia is a common cause of neonatal morbidity and mortality especially in low resource developing countries like Nepal. Early intervention and appropriate management is very crucial for preventing mortality and long-term sequa…
View article: Efficacy of dexmedetomidine with hyperbaric bupivacaine for postoperative analgesia in appendectomy: A randomized controlled trial
Efficacy of dexmedetomidine with hyperbaric bupivacaine for postoperative analgesia in appendectomy: A randomized controlled trial Open
Background: Optimal pain control following surgery plays a vital role in promoting faster recovery. This research explores the effectiveness of adding dexmedetomidine to hyperbaric bupivacaine in enhancing postoperative analgesia for patie…
View article: Complexities in Pediatric Oncology: A Case of Misdiagnosed High‐Grade Glioma Transforming Into Fibrosarcoma
Complexities in Pediatric Oncology: A Case of Misdiagnosed High‐Grade Glioma Transforming Into Fibrosarcoma Open
High‐grade gliomas in pediatric patients can present with nonspecific symptoms and rapid progression. Vigilant monitoring and comprehensive follow‐up are essential, as unexpected diagnoses like fibrosarcoma may complicate management, highl…
View article: Identification of Datura innoxia as a potential source of antimycobacterial components
Identification of Datura innoxia as a potential source of antimycobacterial components Open
Datura innoxia is a medicinal plant from the Solanaceae family, having medicinal properties and some toxic effects. It is widely distributed across Asia, Africa, Europe, the Americas, and other tropical and subtropical regions, where it is…
View article: Uniting for Peace Through Science: A Call to Action from the IJMS and the 4th WCMSR
Uniting for Peace Through Science: A Call to Action from the IJMS and the 4th WCMSR Open
View article: Pharmacogenomics and risk stratification in cardiovascular care: Insights from randomized controlled trials
Pharmacogenomics and risk stratification in cardiovascular care: Insights from randomized controlled trials Open
Genomics and personalized medicine are transforming cardiology by improving the assessment, diagnosis, and treatment of cardiovascular diseases (CVDs). By understanding the genetic factors underlying CVDs, personalized treatment strategies…
View article: Managing Life‐Threatening Tracheal Malignancy and Lung Metastases in a Young Woman: A Case of Aggressive Airway Intervention
Managing Life‐Threatening Tracheal Malignancy and Lung Metastases in a Young Woman: A Case of Aggressive Airway Intervention Open
Infiltrative tracheal malignancies are exceptionally rare among younger individuals, but when they do occur, they present a significant and immediate risk due to severe airway compromise. Managing the airway in such cases is extremely chal…
View article: Comparative efficacy of pre-stented versus non-stented retrograde intrarenal surgery: A randomized controlled trial
Comparative efficacy of pre-stented versus non-stented retrograde intrarenal surgery: A randomized controlled trial Open
Background: Renal stone surgery has been significantly improved by various techniques, with retrograde intrarenal surgery (RIRS) gaining prominence. One potential approach to optimize RIRS outcomes is pre-stenting, where a ureteral stent i…
View article: Revolutionizing chronic rhinosinusitis treatment with functional endoscopic sinus surgery: Insights from a low–middle income country
Revolutionizing chronic rhinosinusitis treatment with functional endoscopic sinus surgery: Insights from a low–middle income country Open
Chronic rhinosinusitis is a common condition that significantly affects quality of life, and functional endoscopic sinus surgery (FESS) has emerged as a widely used, minimally invasive procedure for its treatment. This retrospective study …
View article: Comparative Study of the Efficacy of Alfuzosin and Silodosin in the Medical Expulsion Therapy for Distal Ureteral Calculus
Comparative Study of the Efficacy of Alfuzosin and Silodosin in the Medical Expulsion Therapy for Distal Ureteral Calculus Open
Introduction: Ureteral stones often require pharmacological intervention to aid their passage. Alpha-blockers like Alfuzosin and Silodosin are frequently used to relax ureteral smooth muscle and facilitate stone expulsion. Objectives: The …
View article: Hailey‐Hailey Disease: A Case Report
Hailey‐Hailey Disease: A Case Report Open
Hailey‐Hailey disease should be considered in patients with recurrent, painful, pruritic, vesicular lesions in flexural areas. Early diagnosis through histopathology and immunofluorescence allows effective management with corticosteroids, …