Salil Sharma
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View article: Myocardial fibrosis and calcification are attenuated by microRNA–129-5p targeting Asporin and Sox9 in cardiac fibroblasts
Myocardial fibrosis and calcification are attenuated by microRNA–129-5p targeting Asporin and Sox9 in cardiac fibroblasts Open
Myocardial fibrosis and calcification associate with adverse outcomes in nonischemic heart failure. Cardiac fibroblasts (CF) transition into myofibroblasts (MF) and osteogenic fibroblasts (OF) to promote myocardial fibrosis and calcificati…
View article: microRNAs in Neurodegeneration: Current Findings and Potential Impacts
microRNAs in Neurodegeneration: Current Findings and Potential Impacts Open
Significant advancements have been made in unraveling and understanding the non-coding elements of the human genome. New insights into the structure and function of noncoding RNAs have emerged. Their relevance in the context of both physio…
View article: [P4–040]: ROLE OF MICRORNAS IN ALZHEIMER'S DISEASE (AD)
[P4–040]: ROLE OF MICRORNAS IN ALZHEIMER'S DISEASE (AD) Open
MicroRNAs (miRs) are small non-coding RNA molecules that regulate gene expression. Circulating miRs in the plasma are very stable and are being explored as early-onset biomarkers to detect AD. Indeed, several studies have shown miR changes…
View article: Role of Oxidized Lipids in Pulmonary Arterial Hypertension
Role of Oxidized Lipids in Pulmonary Arterial Hypertension Open
Pulmonary arterial hypertension (PAH) is a multifactorial disease characterized by interplay of many cellular, molecular, and genetic events that lead to excessive proliferation of pulmonary cells, including smooth muscle and endothelial c…