Saliya Gurusinghe
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View article: An Economic Model Evaluating Competitive Wheat Genotypes for Weed Suppression and Yield in a Wheat and Canola Rotation
An Economic Model Evaluating Competitive Wheat Genotypes for Weed Suppression and Yield in a Wheat and Canola Rotation Open
Recurrent selection for early vigour traits in wheat (Triticum aestivum L.) has provided an opportunity to generate competitive biotypes to suppress agronomically important weeds. Quantifying the potential benefits of competitive genotypes…
View article: Impact of Year and Genotype on Benzoxazinoids and Their Microbial Metabolites in the Rhizosphere of Early-Vigour Wheat Genotypes in Southern Australia
Impact of Year and Genotype on Benzoxazinoids and Their Microbial Metabolites in the Rhizosphere of Early-Vigour Wheat Genotypes in Southern Australia Open
Wheat (Triticum aestivum) is grown on more arable acreage than any other food crop and has been well documented to produce allelochemicals. Wheat allelochemicals include numerous benzoxazinoids and their microbially transformed metabolites…
View article: Introgression of early shoot vigour in wheat modifies root systems, increases competitiveness and provides options for integrated weed management
Introgression of early shoot vigour in wheat modifies root systems, increases competitiveness and provides options for integrated weed management Open
Background and aims Weeds are a major biotic stressor impacting crop production. Improving the competitiveness of wheat ( Triticum aestivum L.) could provide a useful tool in integrated weed management. While wheat typically exhibits conse…
Effects of Mixed Pasture Legume Phytoestrogens on Superovulatory Response and Embryo Quality in Angus Cows Open
Ovulation and artificial insemination rates have been observed to decrease in sheep and cows when exposed to dietary phytoestrogens at concentrations greater than 25 mg/kg DM. A grazing trial was undertaken to investigate the effects of co…
Characterisation of Antennal Sensilla and Electroantennography Responses of the Dung Beetles Bubas bison, Onitis aygulus and Geotrupes spiniger (Coleoptera: Scarabaeoidea) to Dung Volatile Organic Compounds Open
Locating sporadically distributed food resources and mate finding are strongly aided by volatile cues for most insects, including dung beetles. However, there is limited information on the olfactory ecology of dung beetles. We conducted a …
Opportunities and Challenges for Cover Cropping in Sustainable Agriculture Systems in Southern Australia Open
Southern Australian farming systems operate predominantly under Mediterranean climatic conditions, which limit the choice of cover crops suitable for enhancement of ground cover and soil moisture retention, erosion control, atmospheric soi…
Dung Beetle Activity Is Soil-Type-Dependent and Modulates Pasture Growth and Associated Soil Microbiome Open
The introduction of numerous exotic dung beetles across southern Australia in regions where native dung beetles are not generally efficient in processing livestock dung has resulted in significant reductions in the quantity of such dung on…
Phytoestrogens: A Review of Their Impacts on Reproductive Physiology and Other Effects upon Grazing Livestock Open
Legume crops and pastures have a high economic value in Australia. However, legume species commonly used for grazing enterprises have been identified to produce high concentrations of phytoestrogens. These compounds are heterocyclic phenol…
View article: Selection for early shoot vigour in wheat increases root hair length but reduces epidermal cell size of roots and leaves
Selection for early shoot vigour in wheat increases root hair length but reduces epidermal cell size of roots and leaves Open
Six cycles of recurrent selection for early shoot vigour in wheat resulted in significant increases in leaf width and shoot biomass. Here, in replicated controlled-environment studies, the effect of early shoot vigour on root biomass, rhiz…
View article: Competitiveness of Early Vigour Wheat (Triticum aestivum L.) Genotypes Is Established at Early Growth Stages
Competitiveness of Early Vigour Wheat (Triticum aestivum L.) Genotypes Is Established at Early Growth Stages Open
Weed competitiveness in wheat (Triticum aestivum L.) has previously been shown to be positively associated with shoot biomass. This study evaluated the impact of increased early shoot vigour on the weed competitiveness of Australian wheats…
Impact of Rotational Sequence Selection on Weed Seedbank Composition in Australian Broadacre Crops Open
The use of competitive crops in successional rotations has been shown to reduce the growth and establishment of annual weeds by the depletion of the weed seedbank in broadacre cropping systems. However, the impact of specific crop rotation…
Characterization of Phytoestrogens in Medicago sativa L. and Grazing Beef Cattle Open
Phytoestrogens are plant-produced bioactive secondary metabolites known to play an integral role in plant defense that frequently accumulate in times of stress and/or microbial infection. Phytoestrogens typically belong to two distinct che…
Toxic Potential and Metabolic Profiling of Two Australian Biotypes of the Invasive Plant Parthenium Weed (Parthenium hysterophorus L.) Open
Parthenium weed (Parthenium hysterophorus L.) is an invasive plant species in around 50 countries and a ‘Weed of National Significance’ in Australia. This study investigated the relative toxicity of the leaf, shoot and root extracts of two…
Metabolic Profiling Provides Unique Insights to Accumulation and Biosynthesis of Key Secondary Metabolites in Annual Pasture Legumes of Mediterranean Origin Open
Annual legumes from the Mediterranean region are receiving attention in Australia as alternatives to traditional pasture species. The current study employed novel metabolic profiling approaches to quantify key secondary metabolites includi…
Neuroprotective Activity of Mentha Species on Hydrogen Peroxide-Induced Apoptosis in SH-SY5Y Cells Open
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with an unclear cause. It appears that multiple factors participate in the process of neuronal damage including oxidative stress and accumulation of the protein amyloid β…
Neuroprotective Activity of <em>Mentha</em> Species on Hydrogen Peroxide-Induced Apoptosis in SH-SY5Y Cells Open
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that develops as a consequence of different factors such as oxidative stress and accumulation of the protein amyloid β (Aβ) in the brain, resulting in apoptosis of neuron…
View article: PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease
PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease Open
Background: Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryologi…
View article: PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease
PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease Open
Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryological gastrula…
View article: Additional file 11 of PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease
Additional file 11 of PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease Open
Additional file 11 File S1. A zip archive containing excel files with the most significant pathways enrichment results from methylomics analysis including those of Fig. S7B, Table S2 and Table S3. The archive unpacks as five separate folde…
View article: PGRMC1 phosphorylation and cell plasticity 2: genomic integrity and CpG methylation
PGRMC1 phosphorylation and cell plasticity 2: genomic integrity and CpG methylation Open
SUMMARY Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryological …
Technologies for the Selection, Culture and Metabolic Profiling of Unique Rhizosphere Microorganisms for Natural Product Discovery Open
Small molecule discovery has benefitted from the development of technologies that have aided in the culture and identification of soil microorganisms and the subsequent analysis of their respective metabolomes. We report herein on the use …
Chemometric analysis of Amaranthus retroflexus in relation to livestock toxicity in southern Australia Open
This dataset contains the digitized treatments in Plazi based on the original journal article Weston, Paul A., Gurusinghe, Saliya, Birckhead, Emily, Skoneczny, Dominik, Quinn, Jane C., Weston, Leslie A. (2019): Chemometric analysis of Amar…
An analysis of rate and factors affecting malignant transformation of oral submucous fibrosis in patients attending the Oral Medicine Clinic, Dental Hospital Peradeniya, Sri Lanka - A retrospective study Open
Background: Oral submucous fibrosis (OSF) is a chronic, progressive, scarring and potentially malignant disease of the oral mucosa seen primarily in the Indian subcontinent and in South East Asia. OSF is a premalignant condition with a mal…