Sally S. Ong
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View article: ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY FOR STAGES 3 AND 4 PROLIFERATIVE SICKLE CELL RETINOPATHY RESULTS IN IMPROVED ANATOMICAL AND VISUAL OUTCOMES
ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY FOR STAGES 3 AND 4 PROLIFERATIVE SICKLE CELL RETINOPATHY RESULTS IN IMPROVED ANATOMICAL AND VISUAL OUTCOMES Open
Purpose: To investigate the potential utility of intravitreal antivascular endothelial growth factor (anti-VEGF) therapy for stages 3 and 4 proliferative sickle cell retinopathy (PSR). Methods: Retrospective review of anatomical and visual…
View article: Intranasal Insulin Mediates Neurodegeneration in Diabetic Retinopathy via Regulation of Inflammatory and Apoptotic Pathways
Intranasal Insulin Mediates Neurodegeneration in Diabetic Retinopathy via Regulation of Inflammatory and Apoptotic Pathways Open
Neurodegenerative changes predominate in early stages of diabetic retinopathy but effective therapies are lacking. Insulin treatment decreases neurodegeneration and intranasal insulin has been shown to reach the central nervous system in n…
View article: Body Fluid-Derived Stem Cells: Powering Innovative, Less-Invasive Cell Therapies
Body Fluid-Derived Stem Cells: Powering Innovative, Less-Invasive Cell Therapies Open
Stem cell therapy offers significant promise for tissue regeneration and repair. Traditionally, bone marrow- and adipose-derived stem cells have served as primary sources, but their clinical use is limited by invasiveness and low cell yiel…
View article: An Automated Frailty Index and Loss to Follow-Up Among Patients With Diabetic Retinopathy
An Automated Frailty Index and Loss to Follow-Up Among Patients With Diabetic Retinopathy Open
This cohort study examines whether patients with diabetic retinopathy who are frail according to an electronic frailty index have higher rates of loss to follow-up compared with less-frail patients.
View article: Neighborhood-Level Social Determinants of Health and Presenting Characteristics for Rhegmatogenous Retinal Detachments
Neighborhood-Level Social Determinants of Health and Presenting Characteristics for Rhegmatogenous Retinal Detachments Open
Importance Functional outcomes after repair of rhegmatogenous retinal detachments (RRDs) are highly dependent on baseline visual acuity and foveal status. Adverse social determinants of health (SDOH) can present barriers to timely presenta…
View article: Association of fractal dimension and other retinal vascular network parameters with cognitive performance and neuroimaging biomarkers: The Multi‐Ethnic Study of Atherosclerosis (MESA)
Association of fractal dimension and other retinal vascular network parameters with cognitive performance and neuroimaging biomarkers: The Multi‐Ethnic Study of Atherosclerosis (MESA) Open
INTRODUCTION Retinal vascular network changes may reflect the integrity of the cerebral microcirculation, and may be associated with cognitive impairment. METHODS Associations of retinal vascular measures with cognitive function and MRI bi…
View article: Socioeconomic disadvantage and impact on visual outcomes in patients with viral retinitis and retinal detachment
Socioeconomic disadvantage and impact on visual outcomes in patients with viral retinitis and retinal detachment Open
While socioeconomic disparities impact clinical care and patient outcomes, t heir impact on the anatomic and visual outcomes of retinal detachment in patients with viral retinitis is unstudied. This case series included 18 eyes in 18 patie…
View article: Socioeconomic Disadvantage and Impact on Visual Outcomes in Patients with Viral Retinitis Associated Retinal Detachment
Socioeconomic Disadvantage and Impact on Visual Outcomes in Patients with Viral Retinitis Associated Retinal Detachment Open
Background: While socioeconomic disparities impact clinical care and patient outcomes, t heir impact on the anatomic and visual outcomes of retinal detachment in patients with viral retinitis is unstudied. Methods: This case series include…
View article: Longitudinal Optical Coherence Tomography Angiography Findings in Malignant Hypertension Choroidopathy: A Case Report
Longitudinal Optical Coherence Tomography Angiography Findings in Malignant Hypertension Choroidopathy: A Case Report Open
This report presented the longitudinal optical coherence tomography angiography (OCTA) findings in a patient with malignant hypertension choroidopathy. An 87-year-old woman presented with acute unilateral central vision loss in the setting…
View article: Treatment of Bilateral Endogenous <b><i>Aspergillus</i></b> Endophthalmitis with Multiple Intravitreal Voriconazole Injections with Good Visual Outcome
Treatment of Bilateral Endogenous <b><i>Aspergillus</i></b> Endophthalmitis with Multiple Intravitreal Voriconazole Injections with Good Visual Outcome Open
Endogenous endophthalmitis caused by Aspergillus species tends to be very aggressive, often leading to devastating visual outcomes. Historically, intravitreal amphotericin injections have played a central role in management, but with varia…
View article: An Evaluation of the Microvasculature of Macular Nodules in Coats Disease Using Optical Coherence Tomography Angiography: A Report of 3 Cases
An Evaluation of the Microvasculature of Macular Nodules in Coats Disease Using Optical Coherence Tomography Angiography: A Report of 3 Cases Open
Purpose: This work aimed to examine the microvasculature of macular fibrosis in Coats disease. Methods: Three boys (aged 3, 4, and 6 years) with Coats disease (stages 2B to 3A2) and macular fibrotic nodules were imaged using optical cohere…
View article: Coats’ Disease
Coats’ Disease Open
Coats' disease is a pediatric vitreoretinopathy that is characterized by the presence of idiopathic retinal vascular telangiectasias with possible retinal exudation and exudative retinal detachments (Shields and Shields 2001). It was first…
View article: Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases
Optical Coherence Tomography Angiography Imaging in Inherited Retinal Diseases Open
Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows depth-resolved imaging of the microvasculature in the retina and the choroid. It is a powerful research tool to study the pathobiology of …
View article: Comparison of Optical Coherence Tomography With Fundus Photographs, Fluorescein Angiography, and Histopathologic Analysis in Assessing Coats Disease
Comparison of Optical Coherence Tomography With Fundus Photographs, Fluorescein Angiography, and Histopathologic Analysis in Assessing Coats Disease Open
Optical coherence tomography may show the transient and permanent effects of Coats disease on the retina. These results suggest that exudates and fluid in the macular subretinal space appear later in the disease and may result in fibrosis …
Macular Features on Spectral-Domain Optical Coherence Tomography Imaging Associated With Visual Acuity in Coats' Disease Open
A compact hyperreflective structure (fibrosis) and ORA were associated with poor final VA while SRF, bright hyperreflectivities (exudation), and foveal subretinal thickness were associated with VA improvement post treatment.