Xin Zheng
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View article: Intracortical microstimulation induces rapid microglia process convergence
Intracortical microstimulation induces rapid microglia process convergence Open
Intracortical microstimulation (ICMS) has the potential to restore vision and hearing by stimulating relevant cortical regions in both animals and humans, offering significant clinical promise for sensory restoration. While the neuronal re…
View article: Association of pan-immune-inflammation value and atherogenic index of plasma with chronic coronary syndrome in non-alcoholic fatty liver disease patients
Association of pan-immune-inflammation value and atherogenic index of plasma with chronic coronary syndrome in non-alcoholic fatty liver disease patients Open
Background Non-alcoholic fatty liver disease (NAFLD) is linked to a higher risk of cardiovascular disease, particularly chronic coronary syndrome (CCS). However, reliable biomarkers for early CCS risk stratification in NAFLD patients remai…
View article: Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES
Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES Open
Background Metabolic Syndrome (MetS) significantly increases the risk of cardiovascular disease (CVD), with central obesity and insulin resistance as major contributors. The TyG-ABSI index is a newly proposed composite measure that combine…
View article: Biodegradation mechanisms of p-nitrophenol and microflora dynamics in fluidized bed bioreactors
Biodegradation mechanisms of p-nitrophenol and microflora dynamics in fluidized bed bioreactors Open
p -Nitrophenol (PNP), a member of the nitroaromatic family, is widely used in the production of pesticides, dyes, pharmaceuticals, and petroleum products. As a toxic compound, PNP is highly resistance to degradation, posing a significant c…
View article: Global visualization of adolescent idiopathic scoliosis treatment: a bibliometric analysis
Global visualization of adolescent idiopathic scoliosis treatment: a bibliometric analysis Open
Objective The objective of this study is to present a comprehensive overview of current advancements, prominent areas of interest, emerging trends, and frontiers in global research concerning the treatment of adolescent idiopathic scoliosi…
View article: Childhood Juvenile idiopathic arthritis combined with Klinefelter syndrome: a case report and literature review
Childhood Juvenile idiopathic arthritis combined with Klinefelter syndrome: a case report and literature review Open
Klinefelter syndrome (KS) is a chromosomal karyotype abnormality, most commonly presenting with the 47,XXY karyotype, and it has been associated with a variety of autoimmune diseases (AD). Juvenile idiopathic arthritis (JIA) is a chronic i…
View article: Longitudinal changes in electrophysiology and widefield calcium imaging following electrode implantation
Longitudinal changes in electrophysiology and widefield calcium imaging following electrode implantation Open
Objective . Intracortical microelectrode arrays often fail to deliver reliable signal quality over chronic recordings, and the effect of an implanted recording array on local neural circuits is not completely understood. Approach . In this…
View article: Association between serum calcium and in-hospital mortality in critically ill atrial fibrillation patients from the MIMIC IV database
Association between serum calcium and in-hospital mortality in critically ill atrial fibrillation patients from the MIMIC IV database Open
View article: Exploration of innovative drug repurposing strategies for combating human protozoan diseases: Advances, challenges, and opportunities
Exploration of innovative drug repurposing strategies for combating human protozoan diseases: Advances, challenges, and opportunities Open
Protozoan infections (e.g., malaria, trypanosomiasis, and toxoplasmosis) pose a considerable global burden on public health and socioeconomic problems, leading to high rates of morbidity and mortality. Due to the limited arsenal of effecti…
View article: Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults
Independent associations of thyroid-related hormones with hepatic steatosis and insulin resistance in euthyroid overweight/obese Chinese adults Open
Purpose The aim of the study is to explore the independent association of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) with hepatic steatosis and insulin resistance. Methods A cross-sectional stud…
View article: Non-weight-bearing short knee radiographs to evaluate coronal alignment before total knee arthroplasty
Non-weight-bearing short knee radiographs to evaluate coronal alignment before total knee arthroplasty Open
For outpatient follow-up, we found that the FTA on NWB SKRs is an acceptable means for classifying knee alignment (varus, neutral, or valgus). The measurement on NWB SKR also showed excellent correlation and good agreement with the HKA. Fo…
View article: A handy skin wound dressing prepared by alginate and cationic nanofibrillated cellulose derived from solid residues of herbs
A handy skin wound dressing prepared by alginate and cationic nanofibrillated cellulose derived from solid residues of herbs Open
Large amounts of solid residues are generated after extraction of active ingredients from herbs for the production of natural medicine, but the residues have not been well utilized. In this work, cationic nanofibrillated cellulose (CCNF) w…
View article: Independent Associations of Thyroid-Related Hormones with Hepatic Steatosis and Insulin Resistance in Euthyroid Overweight/Obese Chinese Adults
Independent Associations of Thyroid-Related Hormones with Hepatic Steatosis and Insulin Resistance in Euthyroid Overweight/Obese Chinese Adults Open
Purpose: The aim of the study is to explore the independent association of free triodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) with hepatic steatosis and insulin resistance. Methods : A cross-sectional st…
View article: Loss to follow-up after surgery in patients with hip fractures
Loss to follow-up after surgery in patients with hip fractures Open
Background: Non-attendance with scheduled postoperative follow-up visits remains a common problem in orthopaedic clinical researches. The goal of this study was to determine the risk factors for loss to follow-up of hip-fracture patients p…
View article: Associations between Osteocalcin, Calciotropic Hormones, and Energy Metabolism in a Cohort of Chinese Postmenopausal Women: Peking Vertebral Fracture Study
Associations between Osteocalcin, Calciotropic Hormones, and Energy Metabolism in a Cohort of Chinese Postmenopausal Women: Peking Vertebral Fracture Study Open
Objective. The endocrine function of bone in energy metabolism may be mediated by the osteocalcin (OC). We examined the association between OC and energy metabolism among Chinese postmenopausal women. Design and Setting. A cross-sectional …
View article: Bone Mineral Density at the Distal Femur and Proximal Tibia and Related Factors During the First Year of Spinal Cord Injury
Bone Mineral Density at the Distal Femur and Proximal Tibia and Related Factors During the First Year of Spinal Cord Injury Open
The rapid loss of BMD at the PT and DF during the first year of SCI occurred significantly earlier than that of the hip. It is recommended to monitor the BMD of DF and PT in early-stage SCI patients, combined with detection of biochemical …
View article: High-Performance Biochar Derived from the Residue of Chaga Mushroom ( <i>Inonotus obliquus</i>) for Pollutants Removal
High-Performance Biochar Derived from the Residue of Chaga Mushroom ( <i>Inonotus obliquus</i>) for Pollutants Removal Open
View article: Correlation Between Daily Energy Intake from Fat with Insulin Resistance in Patients with Polycystic Ovary Syndrome
Correlation Between Daily Energy Intake from Fat with Insulin Resistance in Patients with Polycystic Ovary Syndrome Open
The percentage of daily energy intake from fat is negatively correlated with IR in women with PCOS.
View article: Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome
Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome Open
View article: Association of ESR1 polymorphism rs2234693 and rs9340799 with Postmenopausal osteoporosis in a Chinese Population
Association of ESR1 polymorphism rs2234693 and rs9340799 with Postmenopausal osteoporosis in a Chinese Population Open
Background Postmenopausal osteoporosis (PMO) is the most common type of primary osteoporosis. ESR1 polymorphism rs2234693 and rs9340799 has been widely studied as a candidate gene associated with PMO, however, the findings were inconclusiv…
View article: Evaluation of TaqMan Array Card (TAC) for the Detection of 28 Respiratory Pathogens
Evaluation of TaqMan Array Card (TAC) for the Detection of 28 Respiratory Pathogens Open
Background: Respiratory infections are a serious threat to human health. So, rapid detection of all respiratory pathogens can facilitate prompt treatment and prevent the deterioration of respiratory disease. Previously published primers an…
View article: Effects of Exercise on Blood Glucose and Glycemic Variability in Type 2 Diabetic Patients with Dawn Phenomenon
Effects of Exercise on Blood Glucose and Glycemic Variability in Type 2 Diabetic Patients with Dawn Phenomenon Open
Background . The dawn phenomenon (DP) is the primary cause of difficulty in blood glucose management in type 2 diabetic (T2D) patients, and the use of oral hypoglycemic agents has shown weak efficacy in controlling DP. Thus, this study is …
View article: Nanoparticle Doped PEDOT for Enhanced Electrode Coatings and Drug Delivery
Nanoparticle Doped PEDOT for Enhanced Electrode Coatings and Drug Delivery Open
In order to address material limitations of biologically interfacing electrodes, modified silica nanoparticles are utilized as dopants for conducting polymers. Silica precursors are selected to form a thiol modified particle (TNP), followi…
View article: Fenofibrate modified-release pellets with lag phase and high oral bioavailability
Fenofibrate modified-release pellets with lag phase and high oral bioavailability Open
The modified fenofibrate pellets developed showed enhanced bioavailability and delayed-release properties. They have the potential to improve safety and compliance when co-administrated with statins. This is the first report of a delayed-r…
View article: MSNCs and MgO-MSNCs as drug delivery systems to control the adsorption kinetics and release rate of indometacin
MSNCs and MgO-MSNCs as drug delivery systems to control the adsorption kinetics and release rate of indometacin Open
View article: Ultrasoft microwire neural electrodes improve chronic tissue integration
Ultrasoft microwire neural electrodes improve chronic tissue integration Open
View article: A novel nanogel delivery of poly-α, β-polyasparthydrazide by reverse microemulsion and its redox-responsive release of 5-Fluorouridine
A novel nanogel delivery of poly-α, β-polyasparthydrazide by reverse microemulsion and its redox-responsive release of 5-Fluorouridine Open
To achieve GSH-responsive 5-Fluorouridine (5-FU) delivery, a novel family of nanogel drug carriers has been successfully prepared. The new class of PAHy-based nanogels was prepared by the crossing-link reaction of poly-α, β-polyasparthydra…
View article: Antibiotic-impregnated cement spacer as definitive management for osteomyelitis
Antibiotic-impregnated cement spacer as definitive management for osteomyelitis Open
View article: Mechanism of Angiopoietin-1 Upregulation in Kaposi's Sarcoma-Associated Herpesvirus-Infected PEL Cell Lines
Mechanism of Angiopoietin-1 Upregulation in Kaposi's Sarcoma-Associated Herpesvirus-Infected PEL Cell Lines Open
Angiopoietin-1 (ANGPT-1) is a secreted glycoprotein that was first characterized as a ligand of the Tie2 receptor. In a previous study using microarray analysis, we found that the expression of ANGPT-1 was upregulated in Kaposi's sarcoma-a…