Salvatore Allocca
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Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting: A 12-Month Randomized Trial in Adults with Obesity Open
Background/Objectives: Intermittent fasting and ketogenic dietary approaches are increasingly investigated for their potential metabolic benefits in obesity. However, their long-term neuroendocrine effects—particularly those involving Orex…
Ketogenic diet–induced changes in methylation status and neuropeptide signaling: relationships between S-adenosylmethionine (AdoMet), orexin-A, and metabolic health Open
Introduction S-Adenosylmethionine (AdoMet) is the principal methyl donor in numerous biochemical reactions, regulating lipid and glucose metabolism, inflammatory pathways, and neurotransmitter synthesis. Orexin-A, a hypothalamic neuropepti…
View article: The Effectiveness of Martial Arts Interventions in Autism Spectrum Disorder: A Scoping Review
The Effectiveness of Martial Arts Interventions in Autism Spectrum Disorder: A Scoping Review Open
Background. Autism Spectrum Disorder (ASD) is a neurodevelopmental condition marked by social-communication difficulties, restricted interests, and motor coordination challenges. In recent years, structured physical activity programs — par…
View article: Nutrition and Physical Activity in the University Population: A Scoping Review of Combined Impacts on Psychological Well-Being, Cognitive Performance, and Quality of Life
Nutrition and Physical Activity in the University Population: A Scoping Review of Combined Impacts on Psychological Well-Being, Cognitive Performance, and Quality of Life Open
Background: University students are particularly vulnerable to psychological distress due to the transitional nature of this life phase and increasing academic, social, and financial pressures. Accumulating evidence indicates that lifestyl…
Health-Related Quality of Life and Dietary Supplement Use in Physically Active People and Athletes: A Cross-Sectional Study Open
The use of dietary supplements is widespread among athletes and physically active individuals, yet their impact on health-related quality of life (HRQoL) remains insufficiently understood. This study investigated the associations between s…
Interplay between sex, age, BMI, health-related quality of life, and coping strategies in amateur and professional athletes Open
Background/Objectives The psychological well-being of athletes has garnered increasing interest due to its strong association with physical performance. While somatic indicators such as Body Mass Index (BMI) are routinely monitored in spor…
The Potential Benefits of a Novel Food Supplement Based on Cannabis Sativa, Boswellia, and Fish Oil for Pain and Inflammation in Physical Activity: Unraveling the Role of Orexin-A Modulation Open
Background: Nutraceuticals have emerged as promising alternatives to conventional pharmacological treatments for managing joint pain and low-grade inflammation in physically active individuals. However, few clinical studies have evaluated …
Endocrine and Metabolic Mechanisms Linking Obesity to Type 2 Diabetes: Implications for Targeted Therapy Open
Obesity and Type 2 Diabetes Mellitus (T2DM) are interrelated chronic conditions whose global prevalence continues to rise, posing significant clinical and socioeconomic challenges. Their pathophysiological intersection—commonly referred to…
View article: From Obesity to Mitochondrial Dysfunction in Peripheral Tissues and in the Central Nervous System
From Obesity to Mitochondrial Dysfunction in Peripheral Tissues and in the Central Nervous System Open
Obesity is a condition of chronic low-grade inflammation affecting peripheral organs of the body, as well as the central nervous system. The adipose tissue dysfunction occurring under conditions of obesity is a key factor in the onset and …
Health-Related Quality of Life in Rugby Athletes: The Role of Dietary Supplements and Their Consumption Open
This study investigates dietary supplement use among rugby players and their general health, focusing on prevalence and underlying motivations. Involving 92 athletes, it examines the relationship between supplement usage, motivations, and …
Transcranial Magnetic Stimulation: A New Possibility in Obesity Treatment Open
Obesity is a major public health challenge and results from the complex interaction of many etiopathogenetic factors. However, food-related hedonic stimuli and poor inhibitory control often appear to be specific maintenance factors, and co…
Ultra-Processed Food Intake and Increased Risk of Obesity: A Narrative Review Open
The prevalence of obesity has become a global health concern, with significant impacts on quality of life and mortality rates. Recent research has highlighted the role of ultra-processed foods (UPFs) in driving the obesity epidemic. UPFs u…
Functional Characteristics and Coping Strategies among Rugby Athletes: A Cluster Analysis Approach Open
The developing domain of mental health in sports has gained much interest, acknowledging its pivotal role in athlete performance and well-being. The aim of this research is to provide a quantitative description concerning the levels of men…
The Role of Nutraceutical Supplements, Monacolin K and Astaxanthin, and Diet in Blood Cholesterol Homeostasis in Patients with Myopathy Open
Several studies suggest that different combinations of nutraceutical supplements may improve the lipid profile, representing a viable alternative to statins. However, their effects on individuals with myopathy need to be investigated. The …
Synergistic Interplay between Curcumin and Polyphenol-Rich Foods in the Mediterranean Diet: Therapeutic Prospects for Neurofibromatosis 1 Patients Open
Neurofibromas are the hallmark lesions in Neurofibromatosis 1 (NF1); these tumors are classified as cutaneous, subcutaneous and plexiform. In contrast to cutaneous and subcutaneous neurofibromas, plexiform neurofibromas can grow quickly an…