Salwan Butrus
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View article: Establishing a continuum of cell types in the visual cortex
Establishing a continuum of cell types in the visual cortex Open
The mammalian cerebral cortex is composed of neurons whose properties vary in a continuous fashion rather than falling into discrete cell types. In the mouse visual cortex, excitatory neurons in layer 2 and 3 (L2/3) form such a continuum a…
View article: Molecular states underlying neuronal cell type development and plasticity in the postnatal whisker cortex
Molecular states underlying neuronal cell type development and plasticity in the postnatal whisker cortex Open
Mouse whisker somatosensory cortex (wS1) is a major model system to study the experience-dependent plasticity of cortical neuron physiology, morphology, and sensory coding. However, the role of sensory experience in regulating neuronal cel…
View article: Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex
Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex Open
How early sensory experience during “critical periods” of postnatal life affects the organization of the mammalian neocortex at the resolution of neuronal cell types is poorly understood. We previously reported that the functional and mole…
View article: Molecular states underlying neuronal cell type development and plasticity in the whisker cortex
Molecular states underlying neuronal cell type development and plasticity in the whisker cortex Open
Mouse whisker somatosensory cortex (wS1) is a major model system to study the experience-dependent plasticity of cortical neuron physiology, morphology, and sensory coding. However, the role of sensory experience in regulating neuronal cel…
View article: Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex
Spatial profiling of the interplay between cell type- and vision-dependent transcriptomic programs in the visual cortex Open
How early sensory experience during “critical periods” of postnatal life affects the organization of the mammalian neocortex at the resolution of neuronal cell types is poorly understood. We previously reported that the functional and mole…
View article: HIV silencing and cell survival signatures in infected T cell reservoirs
HIV silencing and cell survival signatures in infected T cell reservoirs Open
View article: Vision-Dependent and -Independent Molecular Maturation of Mouse Retinal Ganglion Cells
Vision-Dependent and -Independent Molecular Maturation of Mouse Retinal Ganglion Cells Open
View article: Vision-dependent and -independent molecular maturation of mouse retinal ganglion cells
Vision-dependent and -independent molecular maturation of mouse retinal ganglion cells Open
The development and connectivity of retinal ganglion cells (RGCs), the retina’s sole output neurons, are patterned by activity-independent transcriptional programs and activity-dependent remodeling. To inventory the molecular correlates of…
View article: Author response: Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types
Author response: Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract The genesis of broad n…
View article: Vision-dependent specification of cell types and function in the developing cortex
Vision-dependent specification of cell types and function in the developing cortex Open
View article: Nanoparticle cellular internalization is not required for RNA delivery to mature plant leaves
Nanoparticle cellular internalization is not required for RNA delivery to mature plant leaves Open
View article: Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types
Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types Open
The genesis of broad neuronal classes from multipotential neural progenitor cells has been extensively studied, but less is known about the diversification of a single neuronal class into multiple types. We used single-cell RNA-seq to stud…
View article: Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves
Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves Open
These datasets are used to produce the figures/graphs published in our article.
View article: Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves
Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves Open
These datasets are used to produce the figures/graphs published in our article.
View article: Vision-dependent specification of cell types and function in the developing cortex
Vision-dependent specification of cell types and function in the developing cortex Open
The role of postnatal experience in sculpting cortical circuitry, while long appreciated, is poorly understood at the level of cell types. We explore this in the mouse primary visual cortex (V1) using single-nucleus RNA-sequencing, visual …
View article: Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves
Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves Open
Rapidly growing interest in nanoparticle-mediated delivery of DNA and RNA to plants requires a better understanding of how nanoparticles and their cargoes translocate in plant tissues and into plant cells. However, little is known about ho…
View article: Vision-dependent specification of cell types and function in the developing cortex
Vision-dependent specification of cell types and function in the developing cortex Open
Data include kernels, SNR values and proportions of functional classes for neurons in Cheng et al., "Vision-dependent specification of cell types and function in the developing cortex", Cell, 2021. For all kern and snr data, each row is a …
View article: Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior
Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior Open
View article: Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior
Molecular classification of zebrafish retinal ganglion cells links genes to cell types to behavior Open
Summary Retinal ganglion cells (RGCs) form an array of feature detectors, which convey visual information to central brain regions. Characterizing RGC diversity is required to understand the logic of the underlying functional segregation. …
View article: Nanoparticle-Mediated Genetic Engineering of Plants
Nanoparticle-Mediated Genetic Engineering of Plants Open