Salzitsa Anastasova
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View article: Multi-Sensory System for Spatially Aware Colonoscopy
Multi-Sensory System for Spatially Aware Colonoscopy Open
View article: Advancements in Cerebrospinal Fluid Biosensors: Bridging the Gap from Early Diagnosis to the Detection of Rare Diseases
Advancements in Cerebrospinal Fluid Biosensors: Bridging the Gap from Early Diagnosis to the Detection of Rare Diseases Open
Cerebrospinal fluid (CSF) is a body fluid that can be used for the diagnosis of various diseases. However, CSF collection requires an invasive and painful procedure called a lumbar puncture (LP). This procedure is applied to any patient wi…
View article: A Multimodal Bio‐Sensing and Imaging Platform (MSIP) for Real‐Time Intraoperative Margin Detection in Cancer Surgery
A Multimodal Bio‐Sensing and Imaging Platform (MSIP) for Real‐Time Intraoperative Margin Detection in Cancer Surgery Open
In cancer surgery, the precise characterisation of tissue margins is of paramount importance to ensure effective resection. However, conventional methods have inherent limitations in terms of both speed and accuracy, often necessitating la…
View article: Development of chitosan, pullulan, and alginate based drug-loaded nano-emulsions as a potential malignant melanoma delivery platform
Development of chitosan, pullulan, and alginate based drug-loaded nano-emulsions as a potential malignant melanoma delivery platform Open
Melanoma is the most aggressive form of skin cancer and various treatments have been investigated to treat this disease, but drug resistance remains an important factor in the failure of conventional therapeutics. Here we describe the deve…
View article: Smart implanted access port catheter for therapy intervention with pH and lactate biosensors
Smart implanted access port catheter for therapy intervention with pH and lactate biosensors Open
Totally implanted access ports (TIAP) are widely used with oncology patients requiring long term central venous access for the delivery of chemotherapeutic agents, infusions, transfusions, blood sample collection and parenteral nutrition. …
View article: Graphene field-effect transistors array for detection of liquid conductivities in the physiological range through novel time-multiplexed impedance measurements
Graphene field-effect transistors array for detection of liquid conductivities in the physiological range through novel time-multiplexed impedance measurements Open
In medical applications, graphene field-effect transistors (GFETs) have been employed as sensors for the detection of biological biomarkers and other compounds due to graphene's high sensitivity towards immobilized molecules at its surface…
View article: Monitoring of Lactate in Interstitial Fluid, Saliva and Sweat by Electrochemical Biosensor: The Uncertainties of Biological Interpretation
Monitoring of Lactate in Interstitial Fluid, Saliva and Sweat by Electrochemical Biosensor: The Uncertainties of Biological Interpretation Open
Lactate electrochemical biosensors were fabricated using Pediococcus sp lactate oxidase (E.C. 1.1.3.2), an external polyurethane membrane laminate diffusion barrier and an internal ionomeric polymer barrier (sulphonated polyether ether sul…
View article: Feasibility Study on Subcutaneously Implanted Devices in Male Rodents for Cardiovascular Assessment Through Near‐Field Communication Interface
Feasibility Study on Subcutaneously Implanted Devices in Male Rodents for Cardiovascular Assessment Through Near‐Field Communication Interface Open
Implantable Devices Bruno Miguel Gil Rosa, Salzitsa Anastasova, and Guang-Zhong Yang demonstrate in article number 2100053 an implantation of a cardiovascular monitoring device inside rodents powered by a mobile phone, with physiological s…
View article: Feasibility Study on Subcutaneously Implanted Devices in Male Rodents for Cardiovascular Assessment Through Near‐Field Communication Interface
Feasibility Study on Subcutaneously Implanted Devices in Male Rodents for Cardiovascular Assessment Through Near‐Field Communication Interface Open
Monitoring of intrabody cardiovascular parameters can benefit from implantation of miniature devices close to anatomical targets, thereby surpassing signal attenuation problems related to the propagation toward body surface while allowing …
View article: Rapid uropathogen identification using surface enhanced Raman spectroscopy active filters
Rapid uropathogen identification using surface enhanced Raman spectroscopy active filters Open
View article: Developing a multimodal biosensor for remote physiological monitoring
Developing a multimodal biosensor for remote physiological monitoring Open
Introduction Several UK military expeditions have successfully used physiological sensors to monitor participant’s physiological responses to challenging environmental conditions. This article describes the development and trial of a multi…
View article: Toward point-of-care uropathogen detection using SERS active filters
Toward point-of-care uropathogen detection using SERS active filters Open
150 million people worldwide suffer one or more urinary tract infections (UTIs) annually. UTIs are a significant health burden: societal costs of UTI exceed $3.5 billion in the U.S. alone; 5% of sepsis cases arise from a urinary source; an…
View article: A Smart Wireless Ear-Worn Device for Cardiovascular and Sweat Parameter Monitoring During Physical Exercise: Design and Performance Results
A Smart Wireless Ear-Worn Device for Cardiovascular and Sweat Parameter Monitoring During Physical Exercise: Design and Performance Results Open
Wearable biomedical technology has gained much support lately as devices have become more affordable to the general public and they can easily interact with mobile phones and other platforms. The feasibility and accuracy of the data genera…
View article: A bio-inspired 3D micro-structure for graphene-based bacteria sensing
A bio-inspired 3D micro-structure for graphene-based bacteria sensing Open
View article: Microgrippers: A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization (Small 16/2018)
Microgrippers: A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization (Small 16/2018) Open
In article number 1703964, Guang-Zhong Yang and co-workers use light from a single mode optical fiber to interrogate the integrated sensor of a compliant microgripper. An applied force results in the spacing of the thin-layer features to c…
View article: A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization
A Monolithic Force‐Sensitive 3D Microgripper Fabricated on the Tip of an Optical Fiber Using 2‐Photon Polymerization Open
Microscale robotic devices have myriad potential applications including drug delivery, biosensing, cell manipulation, and microsurgery. In this work, a tethered, 3D, compliant grasper with an integrated force sensor is presented, the entir…
View article: High temporal resolution delayed analysis of clinical microdialysate streams
High temporal resolution delayed analysis of clinical microdialysate streams Open
This paper presents the use of tubing to store clinical microdialysis samples for delayed analysis with high temporal resolution, offering an alternative to traditional discrete offline microdialysis sampling. A model allowing optimal resu…
View article: The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction
The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction Open
View article: Multi-parametric rigid and flexible, low-cost, disposable sensing platforms for biomedical applications
Multi-parametric rigid and flexible, low-cost, disposable sensing platforms for biomedical applications Open
View article: Corrigendum to “A wearable multisensing patch for continuous sweat monitoring” [Biosens. Bioelectron. (2016)]
Corrigendum to “A wearable multisensing patch for continuous sweat monitoring” [Biosens. Bioelectron. (2016)] Open
View article: A wearable multisensing patch for continuous sweat monitoring
A wearable multisensing patch for continuous sweat monitoring Open
In sport, exercise and healthcare settings, there is a need for continuous, non-invasive monitoring of biomarkers to assess human performance, health and wellbeing. Here we report the development of a flexible microfluidic platform with fu…
View article: 3D Printed Microfluidic Device with Integrated Biosensors for Online Analysis of Subcutaneous Human Microdialysate
3D Printed Microfluidic Device with Integrated Biosensors for Online Analysis of Subcutaneous Human Microdialysate Open
This work presents the design, fabrication, and characterization of a robust 3D printed microfluidic analysis system that integrates with FDA-approved clinical microdialysis probes for continuous monitoring of human tissue metabolite level…
View article: The “Wear and Measure” Approach: Linking Joint Stability Measurements from a Smart Clothing System to Optical Tracking
The “Wear and Measure” Approach: Linking Joint Stability Measurements from a Smart Clothing System to Optical Tracking Open
Joint stability is essential for maintaining normal everyday function. However, assessment of stability often still relies on subjective or obtrusive methods. An unobtrusive approach would be to have our clothes assess our joint stability.…