Sam E. Stephens
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View article: Development and Characteristics of a Dual-Layered Vascular Phantom
Development and Characteristics of a Dual-Layered Vascular Phantom Open
Purpose Cardiovascular phantoms are used in biomedical research and development applications, allowing for complex geometries to be studied in a controlled environment. The various layers of human tissue have been difficult to mimic in the…
View article: Pulse Rate Variability Analysis During Hemorrhage in an Experimental Porcine Model
Pulse Rate Variability Analysis During Hemorrhage in an Experimental Porcine Model Open
Background: The initial response to hemorrhage is mediated by the autonomic nervous system. A method for detecting autonomic nervous system activity may provide the ability to detect acute changes in blood volume. Previous work has indicat…
View article: The Importance of a Continuously Changing Heart Rate in Venous and Arterial Pressure Analysis
The Importance of a Continuously Changing Heart Rate in Venous and Arterial Pressure Analysis Open
Purpose: Previous studies have suggested that minimally invasive peripheral venous and arterial pressure waveforms provide a greater ability to detect acute changes in blood volume than traditional vital signs. Many of these studies are us…
View article: Addressing the barriers to peritoneal dialysis-Visual appeal matters.
Addressing the barriers to peritoneal dialysis-Visual appeal matters. Open
Peritoneal dialysis (PD) is an effective renal replacement strategy for patients with end-stage renal disease utilizing the peritoneum as the filter and PD catheter as access. A survey of PD patients showed that some felt uncomfortable wit…
View article: Design, fabrication, and evaluation of 3-D–printed cystotomy spoons as a retrieval method in dogs
Design, fabrication, and evaluation of 3-D–printed cystotomy spoons as a retrieval method in dogs Open
OBJECTIVE Current cystotomy methods often implement the use of off-label devices, resulting in urocystolith extraction difficulty and potentially leading to postoperative complications and discomfort for the patient. The objective of this …
View article: In Vitro Blood Clot Formation and Dissolution for Testing New Stroke-Treatment Devices
In Vitro Blood Clot Formation and Dissolution for Testing New Stroke-Treatment Devices Open
Strokes are among the leading causes of death worldwide. Ischemic stroke, due to plaque or other buildup blocking blood flow to the brain, is the most common type. Although ischemic stroke is treatable, current methods have severe shortcom…
View article: In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure
In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure Open
Current in vitro models of the left heart establish the pressure difference required to close the mitral valve by sealing and pressurizing the ventricular side of the valve, limiting important access to the subvalvular apparatus. This pape…
View article: Development of Custom Wall-Less Cardiovascular Flow Phantoms with Tissue-Mimicking Gel
Development of Custom Wall-Less Cardiovascular Flow Phantoms with Tissue-Mimicking Gel Open
Purpose Flow phantoms are used in experimental settings to aid in the simulation of blood flow. Custom geometries are available, but current phantom materials present issues with degradability and/or mimicking the mechanical properties of …
View article: Author Correction: Simulating nephron ion transport function using activated wafer electrodeionization
Author Correction: Simulating nephron ion transport function using activated wafer electrodeionization Open
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View article: Simulating nephron ion transport function using activated wafer electrodeionization
Simulating nephron ion transport function using activated wafer electrodeionization Open
Current approaches for treating patients with end stage renal disease include hemodialysis and peritoneal dialysis, both of which are diffusion-based treatments that require a dialysate solution. The native kidney has separate filtration (…
View article: Bonding Mitral Valve Leaflets in the Closed Configuration for High Resolution Micro-CT Imaging
Bonding Mitral Valve Leaflets in the Closed Configuration for High Resolution Micro-CT Imaging Open
Objective: Computational models of the mitral valve (MV) have the potential to accurately predict behavior of tissues and devices, but require high quality imagery for validation. Of particular technical difficulty, is imaging the closed v…
View article: High resolution imaging of the mitral valve in the natural state with 7 Tesla MRI
High resolution imaging of the mitral valve in the natural state with 7 Tesla MRI Open
Imaging techniques of the mitral valve have improved tremendously during the last decade, but challenges persist. The delicate changes in annulus shape and papillary muscle position throughout the cardiac cycle have significant impact on t…