Sam Jonathan Marks
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View article: TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer
TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer Open
Background Natural killer (NK) cells provide important immune protection from cancer and are a key requirement for particular immunotherapies. There is accumulating evidence that NK cells become dysfunctional during cancer. Overcoming NK c…
View article: TGFβ drives mitochondrial dysfunction in peripheral blood NK cells during metastatic breast cancer
TGFβ drives mitochondrial dysfunction in peripheral blood NK cells during metastatic breast cancer Open
Natural Killer (NK) cells provide important protection from cancer and are a key requirement for particular immunotherapies. In activated NK cells, a metabolic response towards increased glycolysis and oxidative phosphorylation is crucial …