Sam Leary
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View article: Cleft@18–23 study research clinics: a protocol for a multicentre observational study across UK cleft centres to understand variation in outcomes at the end of routine cleft care
Cleft@18–23 study research clinics: a protocol for a multicentre observational study across UK cleft centres to understand variation in outcomes at the end of routine cleft care Open
Introduction Cleft lip and/or palate (CL/P) is a lifelong condition affecting one in 700 births. In the UK, individuals born with CL/P follow a care pathway at specialist regional cleft centres, which includes input from a range of profess…
View article: Associations Between Eating Windows and Health Outcomes in Children and Adolescents from the ALSPAC Cohort
Associations Between Eating Windows and Health Outcomes in Children and Adolescents from the ALSPAC Cohort Open
Background: Time-limited eating (TLE) improves body weight and metabolic health in adults; however, little is known about effects in younger populations (YP). TLE in adolescents can reduce calorie consumption, but studies have not demonstr…
View article: Associations of waist circumference to height ratio and body mass index through childhood and adolescence on blood pressure and risk of young adult hepatic steatosis: a cohort study
Associations of waist circumference to height ratio and body mass index through childhood and adolescence on blood pressure and risk of young adult hepatic steatosis: a cohort study Open
Objective Body mass index (BMI), and its adjustment for age and sex as a z-score, is a common measure of excess weight but performs poorly in children. Waist circumference to height ratio (WHtR), which reflects excess adiposity, may be a u…
View article: Effect of early life income and sugars intake on child oral health – marginal structural modelling using a birth cohort study
Effect of early life income and sugars intake on child oral health – marginal structural modelling using a birth cohort study Open
Introduction: Determinants of oral health are formed early and influenced by variations in socioeconomic status (SES). It is unclear whether early-life SES influences child oral health directly, or indirectly through determinants such as i…
View article: The Postgraduate Educational Environment at a United Kingdom Dental School: A Quantitative Study Using a Modified Dundee Ready Educational Environment Measure Questionnaire
The Postgraduate Educational Environment at a United Kingdom Dental School: A Quantitative Study Using a Modified Dundee Ready Educational Environment Measure Questionnaire Open
Introduction Quantitative research on postgraduate (PG) dental students' perceptions of their educational environment is lacking. The aim of this research was to increase our understanding of taught PG dental students' educational environm…
View article: Early Childhood Exposures to Fluorides and Cognitive Neurodevelopment: A Population-Based Longitudinal Study
Early Childhood Exposures to Fluorides and Cognitive Neurodevelopment: A Population-Based Longitudinal Study Open
It is important to maintain confidence in the risk and benefit balance of major caries-preventive programs using fluoride. The ongoing debate about potential effects of early-life exposures to fluoride on cognitive neurodevelopment require…
View article: Association between overweight/obesity and dental outcomes in early childhood: Findings from an Australian cohort study
Association between overweight/obesity and dental outcomes in early childhood: Findings from an Australian cohort study Open
Objectives Oral health is an important part of general health and well‐being and shares risk factors, such as poor diet, with obesity. The published literature assessing the association between obesity and oral health in early childhood is…
View article: Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort
Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort Open
Later eating rhythm (LER) refers to later timing, greater energy intake (EI), and higher frequency of eating occasions (meal/snack) in the evening. The significance of LER in child health is becoming increasingly recognised. However, the l…
View article: Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort
Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort Open
Later eating rhythm (LER) refers to later timing, greater energy intake (EI), and higher frequency of eating occasions (meal/snack) in the evening. The significance of LER in child health is becoming increasingly recognised. However, the l…
View article: What is the usual eating window for children and adolescents aged 6-20 years: a systematic review
What is the usual eating window for children and adolescents aged 6-20 years: a systematic review Open
This abstract was awarded the Student Competition prize. Time-limited eating is a dietary intervention whereby calorie intake is limited to a specific window of time during the day (1) . The usual eating windows (EW) of adults, and how thi…
View article: Daily Duration of Eating for Children and Adolescents: A Systematic Review and Meta-Analysis
Daily Duration of Eating for Children and Adolescents: A Systematic Review and Meta-Analysis Open
Time-limited eating is a dietary intervention whereby eating is limited to a specific window of time during the day. The usual eating windows of adults, and how these can be manipulated for dietary interventions, is well documented. Howeve…
View article: Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort
Later eating rhythm measured in children at 7 years of age in the ALSPAC cohort Open
Later eating rhythm (LER) refers to later timing, greater energy intake (EI), and higher frequency of eating occasions (meal/snack) in the evening. The significance of LER in child health is becoming increasingly recognised. However, the l…
View article: Should left‐ and right‐sided unilateral cleft lip and palate patients be grouped together when reporting the outcomes?
Should left‐ and right‐sided unilateral cleft lip and palate patients be grouped together when reporting the outcomes? Open
Objectives Investigate associations between cleft laterality in patients with non‐syndromic unilateral cleft lip and palate (UCLP) and oral‐health, dental‐arch, speech, audiological, psychological and nasolabial‐aesthetic outcomes. Methods…
View article: Associations between body mass index and episodic memory for recent eating, mindful eating, and cognitive distraction: A cross‐sectional study
Associations between body mass index and episodic memory for recent eating, mindful eating, and cognitive distraction: A cross‐sectional study Open
Objectives Eating while distracted has been associated with a higher body mass index (BMI), whereas mindful eating and episodic memory for recent eating have shown the opposite pattern. This pre‐registered, global study ( https://osf.io/rd…
View article: ‘‘I felt marvellous e-cycling. If I had long hair I would have flicked it”: a qualitative investigation of the factors associated with e-cycling engagement among adults with type 2 diabetes
‘‘I felt marvellous e-cycling. If I had long hair I would have flicked it”: a qualitative investigation of the factors associated with e-cycling engagement among adults with type 2 diabetes Open
Background Physical activity (PA) is a key component in the management of type 2 diabetes. However, this population have low rates of PA engagement. Electrically assisted cycling has been identified as a means through which to increase PA …
View article: Association between 6-thioguanine nucleotide levels and preventing production of antibodies to infliximab in patients with inflammatory bowel disease
Association between 6-thioguanine nucleotide levels and preventing production of antibodies to infliximab in patients with inflammatory bowel disease Open
Objective Combination therapy with infliximab and a thiopurine has been shown to be more effective than monotherapy in patients with inflammatory bowel disease (IBD). The therapeutic efficacy of thiopurines is correlated with 6-thioguanine…
View article: The Role of the Mediterranean Diet in Breast Cancer Survivorship: A Systematic Review and Meta-Analysis of Observational Studies and Randomised Controlled Trials
The Role of the Mediterranean Diet in Breast Cancer Survivorship: A Systematic Review and Meta-Analysis of Observational Studies and Randomised Controlled Trials Open
Female breast cancer is the most frequently diagnosed cancer. The long-term survival rates for this disease have increased; however, the unique demand for high-quality healthcare to improve breast-cancer survivorship are commonly unmet. Th…
View article: Data from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology
Data from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology Open
A rising incidence of oropharyngeal squamous cell carcinoma (OPSCC) incidence has occurred throughout the developed world, where it has been attributed to an increasing impact of human papillomavirus (HPV) on disease etiology. This report …
View article: Data from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology
Data from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology Open
A rising incidence of oropharyngeal squamous cell carcinoma (OPSCC) incidence has occurred throughout the developed world, where it has been attributed to an increasing impact of human papillomavirus (HPV) on disease etiology. This report …
View article: Supplemental Tables 1 through 3 from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology
Supplemental Tables 1 through 3 from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology Open
Supplementary Table S1. Age and gender comparison between the current study and the UK incidence data (2002-2011); Supplementary Table S2. Comparison of age distribution in cases from 2002-2006 vs. 2007-2011; Supplementary Table S3. Type-s…
View article: Supplemental Tables 1 through 3 from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology
Supplemental Tables 1 through 3 from HPV-Related Oropharynx Cancer in the United Kingdom: An Evolution in the Understanding of Disease Etiology Open
Supplementary Table S1. Age and gender comparison between the current study and the UK incidence data (2002-2011); Supplementary Table S2. Comparison of age distribution in cases from 2002-2006 vs. 2007-2011; Supplementary Table S3. Type-s…
View article: Establishing breast feeding in infants with Down syndrome: the FADES cohort experience
Establishing breast feeding in infants with Down syndrome: the FADES cohort experience Open
Objective To describe breastfeeding prevalence and maternal experience in infants with trisomy 21. Design Longitudinal cohort study. Setting Participants from UK recruited through websites, social media and local collaborators: neonatologi…
View article: A Randomised Trial of Ultrasonographic Assessment of Gastric Emptying Following Water Ingestion in Healthy Volunteers
A Randomised Trial of Ultrasonographic Assessment of Gastric Emptying Following Water Ingestion in Healthy Volunteers Open
Background: Current guidance on pre-operative fasting for clear fluids to reduce aspiration risk may result in unnecessary dehydration and more liberal fluid regimes are being advocated. Methods: This randomised single blinded crossover st…