Sam Ratnam
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View article: A pooled analysis to compare the clinical characteristics of human papillomavirus–positive and -negative cervical precancers
A pooled analysis to compare the clinical characteristics of human papillomavirus–positive and -negative cervical precancers Open
Given that high-risk human papillomavirus (HPV) is the necessary cause of virtually all cervical cancer, the clinical meaning of HPV-negative cervical precancer is unknown. We, therefore, conducted a literature search in Ovid MEDLINE, PubM…
View article: Supplementary Material from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results
Supplementary Material from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results Open
Supplemental Table 1. Performance of Triage Strategies for the Detection of CIN3+ Among HR-HPV+ Women. Supplemental Table 2. Performance of Additional Triage Strategies for the Detection of CIN2+ Among HR-HPV+ Women.
View article: Data from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results
Data from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results Open
Background: High-risk human papillomavirus (HR-HPV) testing has become a preferred cervical cancer screening strategy in some countries due to its superior sensitivity over cytology-based methods for identifying cervical intraepithelial ne…
View article: Supplementary Material from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results
Supplementary Material from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results Open
Supplemental Table 1. Performance of Triage Strategies for the Detection of CIN3+ Among HR-HPV+ Women. Supplemental Table 2. Performance of Additional Triage Strategies for the Detection of CIN2+ Among HR-HPV+ Women.
View article: Data from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results
Data from Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results Open
Background: High-risk human papillomavirus (HR-HPV) testing has become a preferred cervical cancer screening strategy in some countries due to its superior sensitivity over cytology-based methods for identifying cervical intraepithelial ne…
Comparison of Alinity m HPV and cobas HPV assays on cervical specimens in diverse storage media Open
Compared to cobas, Alinity performed equally well for detecting HPV in cervical specimens obtained with ThinPrep and SurePath. The Cervi-Collect device compared well to the other collection methods. Alinity is a reliable assay for simultan…
Comparison of Assays for the Diagnosis of Mycoplasma genitalium and Macrolide Resistance Mutations in Self-Collected Vaginal Swabs and Urine Open
Background The objective was to compare commercial assays on clinical specimens for Mycoplasma genitalium (MG) detection and macrolide resistance mutation (MRM) frequency. Methods Three self-collected vaginal swabs (VS) and a first-void ur…
CINtec PLUS and cobas HPV testing for triaging Canadian women referred to colposcopy with a history of low-grade squamous intraepithelial lesion: Baseline findings Open
OBJECTIVE AND METHODS: CINtec PLUS and cobas HPV tests were assessed for triaging women referred to colposcopy with a history of LSIL cytology. Both tests were performed at baseline using ThinPrep cervical specimens and biopsy confirmed ce…
View article: Assessing the time dependence of prognostic values of cytology and human papillomavirus testing in cervical cancer screening
Assessing the time dependence of prognostic values of cytology and human papillomavirus testing in cervical cancer screening Open
Accurate assessment of risks for developing cervical intraepithelial neoplasia of grade 2 or worse (CIN2+) after a given set of screening test results is instrumental to reaching valid conclusions and informing cervical cancer screening re…
Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing Open
Since implementation of the 13-valent polyvalent conjugate vaccine (PCV13) in Canada during 2010, the proportion of PCV13 serotypes causing invasive pneumococcal disease (IPD) has declined from 55% (n = 1492) in 2010 to 31% (n = 764) in 20…
View article: Detection of cervical precancerous lesions with Aptima HPV assays using SurePath preservative fluid specimens
Detection of cervical precancerous lesions with Aptima HPV assays using SurePath preservative fluid specimens Open
SurePath specimens from women referred to colposcopy were treated with Aptima Transfer Solution (ATS) before testing in Aptima HPV (AHPV) and Aptima HPV 16, 18/45 (AHPV-GT) assays. Untreated SurePath specimens were tested with the cobas HP…
View article: Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results
Comparison of Triage Strategies for HPV-Positive Women: Canadian Cervical Cancer Screening Trial Results Open
Background: High-risk human papillomavirus (HR-HPV) testing has become a preferred cervical cancer screening strategy in some countries due to its superior sensitivity over cytology-based methods for identifying cervical intraepithelial ne…
View article: Human papillomavirus testing versus cytology in primary cervical cancer screening: End‐of‐study and extended follow‐up results from the Canadian cervical cancer screening trial
Human papillomavirus testing versus cytology in primary cervical cancer screening: End‐of‐study and extended follow‐up results from the Canadian cervical cancer screening trial Open
The Canadian Cervical Cancer Screening Trial was a randomized controlled trial comparing the performance of human papillomavirus (HPV) testing and Papanicolaou cytology to detect cervical intraepithelial neoplasia of grades 2 or worse (CIN…
View article: Phenotypic H-Antigen Typing by Mass Spectrometry Combined with Genetic Typing of H Antigens, O Antigens, and Toxins by Whole-Genome Sequencing Enhances Identification of Escherichia coli Isolates
Phenotypic H-Antigen Typing by Mass Spectrometry Combined with Genetic Typing of H Antigens, O Antigens, and Toxins by Whole-Genome Sequencing Enhances Identification of Escherichia coli Isolates Open
Mass spectrometry-based phenotypic H-antigen typing (MS-H) combined with whole-genome-sequencing-based genetic identification of H antigens, O antigens, and toxins (WGS-HOT) was used to type 60 clinical Escherichia coli isolates, 43 of whi…