Samad Nadri
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View article: Free and encapsulated stem cells for skin regeneration
Free and encapsulated stem cells for skin regeneration Open
Optimal skin healing is a sophisticated, coordinated process involving cellular and molecular interactions. Disruptions in this process can result in chronic wounds, necessitating medical intervention, particularly when the damage surpasse…
View article: Molecular dynamics simulation in tissue engineering
Molecular dynamics simulation in tissue engineering Open
Introduction: In tissue engineering, the interaction among three primary elements, namely cells, material scaffolds, and stimuli, plays a pivotal role in determining the fate of cells and the formation of new tissue. Understanding the char…
View article: Microfluidics as a promising technology for personalized medicine
Microfluidics as a promising technology for personalized medicine Open
Introduction: Due to the recent advances in biomedicine and the increasing understanding of the molecular mechanism of diseases, healthcare approaches have tended towards preventive and personalized medicine. Consequently, in recent decade…
View article: Alpha-Synuclein Clearance through Inhibiting Akt/mTOR Pathway by Microfluidic Encapsulated Induced Conjunctival MSCs in a Parkinsonian Model
Alpha-Synuclein Clearance through Inhibiting Akt/mTOR Pathway by Microfluidic Encapsulated Induced Conjunctival MSCs in a Parkinsonian Model Open
It seems that CJ-MSCs can promote the degradation of intracellular α-Syn by miR-149-5p/Akt/mTOR pathway and improve rats' motor functions.
View article: Prevention of peritoneal adhesions formation by core-shell electrospun ibuprofen-loaded PEG/silk fibrous membrane
Prevention of peritoneal adhesions formation by core-shell electrospun ibuprofen-loaded PEG/silk fibrous membrane Open
Adhesion bands are pathological fibrous tissues that create in the middle of tissues and organs, often reasons of intestinal obstruction, and female infertility. Here, we explored the anti-adhesive and inflammatory capacities of PEG/silk a…
View article: Neuroprotective Effects of Microfluidic Encapsulated Induced Conjunctival Mesenchymal Stem Cells Through Autophagy Modulation in a Parkinsonian Model
Neuroprotective Effects of Microfluidic Encapsulated Induced Conjunctival Mesenchymal Stem Cells Through Autophagy Modulation in a Parkinsonian Model Open
Background and Aim: Parkinson's disease (PD) is a progressive neurodegenerative disorder in which cause is attributed to the alpha-synuclein (α-Syn) accumulation due to the decreases rated of autophagy. According to recent studies, cell th…
View article: Retinoic acid –loaded core-shell fibrous scaffold for neuronal differentiation of trabecular mesenchymal stem cells
Retinoic acid –loaded core-shell fibrous scaffold for neuronal differentiation of trabecular mesenchymal stem cells Open
Objective(s): Scientists believe that they can fabricate a biochemical scaffold and seed stem cells on it to create an extracellular matrix for tissue generation. This study sought to develop retinoic acid (RA)-loaded core-shell fibrous sc…
View article: Microfluidic synthesis of retinoic acid-loaded nanoparticles for neural differentiation of trabecular meshwork mesenchymal stem cell
Microfluidic synthesis of retinoic acid-loaded nanoparticles for neural differentiation of trabecular meshwork mesenchymal stem cell Open
Our study's harvested results have represented valid data for practical use of microfluidic systems in the term of NPs loaded RA synthesis and its successful function to cellular internalization and euronal differentiation of TMMSCs (Tab. …
View article: Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids:<i> In vitro</i> and <i>in silico</i> approach
Role of cellulose family in fibril organization of collagen for forming 3D cancer spheroids:<i> In vitro</i> and <i>in silico</i> approach Open
Introduction: Cell aggregation of three-dimensional (3D) culture systems (the so-called spheroids) are designed as in vitro platform to represent more accurately the in vivo environment for drug discovery by using semi-solid media. The uni…
View article: Repair of rat cranial bone defect by using amniotic fluid-derived mesenchymal stem cells in polycaprolactone fibrous scaffolds and platelet-rich plasma
Repair of rat cranial bone defect by using amniotic fluid-derived mesenchymal stem cells in polycaprolactone fibrous scaffolds and platelet-rich plasma Open
Introduction: Tissue regenerative medicine strategies, as a promising alternative has become of major interest to the reconstruction of critical size bone defects. This study evaluated the effects of the simultaneous application of polycap…
View article: Placenta mesenchymal stem cells differentiation toward neuronal-like cells on nanofibrous scaffold
Placenta mesenchymal stem cells differentiation toward neuronal-like cells on nanofibrous scaffold Open
Introduction: Transplantation of stem cells with a nanofibrous scaffold is a promising approach for spinal cord injury therapy. The aim of this work was to differentiate neural-like cells from placenta-derived mesenchymal stem cells (PDMSC…
View article: Effect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells.
Effect of let-7a overexpression on the differentiation of conjunctiva mesenchymal stem cells into photoreceptor-like cells. Open
Our findings indicate that overexpression of let-7a microRNA can increase the expression of photoreceptor-specific genes in CJMSCs. Moreover, it is prospective that let-7a overexpression can use as an alternative protocol for the different…
View article: Ex Vivo Expansion of Umbilical Cord Blood Hematopoietic Stem Cells on Collagen- Fibronectin Coated Electrospun Nano Scaffold
Ex Vivo Expansion of Umbilical Cord Blood Hematopoietic Stem Cells on Collagen- Fibronectin Coated Electrospun Nano Scaffold Open
View article: Generation of insulin-producing cells from human induced pluripotent stem cells on PLLA/PVA nanofiber scaffold
Generation of insulin-producing cells from human induced pluripotent stem cells on PLLA/PVA nanofiber scaffold Open
Pancreatic tissue engineering as a therapeutic option for restoring and maintenance of damaged pancreas function has a special focus to using synthetic Scaffolds. This study was designed to evaluate pancreatic differentiation of human indu…
View article: Differentiation of conjunctiva mesenchymal stem cells into secreting islet beta cells on plasma treated electrospun nanofibrous scaffold
Differentiation of conjunctiva mesenchymal stem cells into secreting islet beta cells on plasma treated electrospun nanofibrous scaffold Open
Transplantation of stem cells using biocompatible nanofibrous scaffolds is a promising therapeutic method for treating Diabetic Mellitus. The aim of this study was to derive insulin-producing cells (IPCs) from conjunctiva-derived mesenchym…
View article: shRNA-mediated downregulation of α-N-Acetylgalactosaminidase inhibits migration and invasion of cancer cell lines.
shRNA-mediated downregulation of α-N-Acetylgalactosaminidase inhibits migration and invasion of cancer cell lines. Open
These results indicate that Nagalase may have an important role in migration and invasion of cancer cells and can be considered as a candidate for further studies.
View article: Fibrin gel as a scaffold for photoreceptor cells differentiation from conjunctiva mesenchymal stem cells in retina tissue engineering
Fibrin gel as a scaffold for photoreceptor cells differentiation from conjunctiva mesenchymal stem cells in retina tissue engineering Open
Stem cell-based therapies are attraction approaches for regenerative medicine for treating retinal diseases. One of the limitations in cell therapy is cell death following post-injection whit preventing functional integration with retinal …
View article: Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review
Isolation Methods of Mesenchymal Stem Cells in Mice; a Systematic Review Open
Bone marrow (BM) has been regarded as the primarily source of hematopoietic stem cells for many years. Recent researches have shown BM contains not only hematopoietic but also heterogeneous non-hematopoietic stem cells. Till now, similar o…