Samantha Arokiasamy
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View article: QM107, a novel CD148 (RTP Type J) activating peptide therapy for treating neovascular age‐related macular degeneration
QM107, a novel CD148 (RTP Type J) activating peptide therapy for treating neovascular age‐related macular degeneration Open
Background and Purpose Angiogenesis is a pathological component of neovascular age‐related macular degeneration. Current therapies, although successful, are prone to high levels of patient non‐response and a loss of efficacy over time, ind…
View article: Novel application of live imaging to determine the functional cell biology of endothelial-to-mesenchymal transition (EndMT) within a liver-on-a-chip platform
Novel application of live imaging to determine the functional cell biology of endothelial-to-mesenchymal transition (EndMT) within a liver-on-a-chip platform Open
View article: Roles of Syndecan-4 in cardiac injury and repair
Roles of Syndecan-4 in cardiac injury and repair Open
View article: Pathological Angiogenesis Requires Syndecan-4 for Efficient VEGFA-Induced VE-Cadherin Internalization
Pathological Angiogenesis Requires Syndecan-4 for Efficient VEGFA-Induced VE-Cadherin Internalization Open
Objective: VEGFA (Vascular endothelial growth factor A) and its receptor VEGFR2 (vascular endothelial growth factor receptor 2) drive angiogenesis in several pathologies, including diabetic retinopathy, wet age-related macular degeneration…
View article: Syndecan receptors: pericellular regulators in development and inflammatory disease
Syndecan receptors: pericellular regulators in development and inflammatory disease Open
The syndecans are the major family of transmembrane proteoglycans, usually bearing multiple heparan sulfate chains. They are present on virtually all nucleated cells of vertebrates and are also present in invertebrates, indicative of a lon…
View article: Syndecan-3 in Inflammation and Angiogenesis
Syndecan-3 in Inflammation and Angiogenesis Open
Syndecans are a four member multifunctional family of cell surface molecules with diverse biological roles. Syndecan-3 (SDC3) is the largest of these, but in comparison to the other family members relatively little is known about this mole…
View article: Heparanase-Dependent Remodeling of Initial Lymphatic Glycocalyx Regulates Tissue-Fluid Drainage During Acute Inflammation in vivo
Heparanase-Dependent Remodeling of Initial Lymphatic Glycocalyx Regulates Tissue-Fluid Drainage During Acute Inflammation in vivo Open
The glycocalyx is a dense layer of carbohydrate chains involved in numerous and fundamental biological processes, such as cellular and tissue homeostasis, inflammation and disease development. Composed of membrane-bound glycoproteins, sulf…
View article: Translating the matrix
Translating the matrix Open
Linked Articles This article is part of a themed section on Translating the Matrix. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.1/issuetoc
View article: Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation
Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation Open
View article: An investigation into the regulatory mechanisms of neutrophil migration into lymphatic vessels in vivo
An investigation into the regulatory mechanisms of neutrophil migration into lymphatic vessels in vivo Open