Sameer Gabbita
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View article: The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions
The craniofacial shape of modern humans embodies genomic signatures of evolution, diversity, and clinical conditions Open
Human craniofacial morphology is a hallmark of our species’ diversity and evolutionary history, shaped by adaptation, introgression, and global dispersal. Cranial globularization and chin emergence are well-documented morphological transfo…
View article: A multi-analyte blood test for acute spinal cord injury
A multi-analyte blood test for acute spinal cord injury Open
BACKGROUNDRapid diagnosis to facilitate urgent intervention is critical for treatment of acute spinal cord injury (SCI). We hypothesized that a multi-analyte blood biomarker would support point-of-care SCI diagnosis, correlate with injury …
View article: Insights to aging prediction with AI based epigenetic clocks
Insights to aging prediction with AI based epigenetic clocks Open
Over the past century, human lifespan has increased remarkably, yet the inevitability of aging persists. The disparity between biological age, which reflects pathological deterioration and disease, and chronological age, indicative of norm…
View article: DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements
DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements Open
The challenge of systematically modifying and optimizing regulatory elements for precise gene expression control is central to modern genomics and synthetic biology. Advancements in generative AI have paved the way for designing synthetic …