Sameer Sundrani
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View article: Venous sinus stenting versus ventriculoperitoneal shunting: Comparing perioperative costs for idiopathic intracranial hypertension
Venous sinus stenting versus ventriculoperitoneal shunting: Comparing perioperative costs for idiopathic intracranial hypertension Open
Introduction Venous sinus stenting (VSS) is an effective, less invasive alternative to ventriculoperitoneal shunting (VPS) for idiopathic intracranial hypertension (IIH). While efficacy is comparable, with some evidence favoring VSS for he…
View article: Human-centered design of an artificial intelligence monitoring system: the Vanderbilt Algorithmovigilance Monitoring and Operations System
Human-centered design of an artificial intelligence monitoring system: the Vanderbilt Algorithmovigilance Monitoring and Operations System Open
Objectives As the use of artificial intelligence (AI) in healthcare is rapidly expanding, there is also growing recognition of the need for ongoing monitoring of AI after implementation, called algorithmovigilance. Yet, there remain few sy…
View article: Does alignment alone predict mechanical complications after adult spinal deformity surgery? A machine learning comparison of alignment, bone quality, and soft tissue
Does alignment alone predict mechanical complications after adult spinal deformity surgery? A machine learning comparison of alignment, bone quality, and soft tissue Open
OBJECTIVE Mechanical complications are a vexing occurrence after adult spinal deformity (ASD) surgery. While achieving ideal spinal alignment in ASD surgery is critical, alignment alone may not fully explain all mechanical complications. T…
View article: Human-Centered Design of an Artificial Intelligence (AI) Monitoring System: The Vanderbilt Algorithmovigilance Monitoring and Operations System (VAMOS)
Human-Centered Design of an Artificial Intelligence (AI) Monitoring System: The Vanderbilt Algorithmovigilance Monitoring and Operations System (VAMOS) Open
Background. As the use of AI in healthcare is rapidly expanding, there is also growing recognition of the need for ongoing monitoring of AI after implementation, called algorithmovigilance . Yet, there remain few systems that support syste…
View article: Deep learning on brief interictal intracranial recordings can accurately characterize seizure onset zones
Deep learning on brief interictal intracranial recordings can accurately characterize seizure onset zones Open
Objective Epilepsy is a debilitating disorder affecting more than 50 million people worldwide, and one third of patients continue to have seizures despite maximal medical management. If patients' seizures localize to a discrete brain regio…
View article: Emergency neoplastic spinal cord compression without known histology: should we operate?
Emergency neoplastic spinal cord compression without known histology: should we operate? Open
OBJECTIVE Patients presenting emergently with neoplastic spinal cord compression without known histology pose a complex decision for spine surgeons. In this patient population, the authors sought to 1) describe presentation/histology, 2) d…
View article: DNA Polymerase Diversity Reveals Multiple Incursions of Polintons During Nematode Evolution
DNA Polymerase Diversity Reveals Multiple Incursions of Polintons During Nematode Evolution Open
Polintons are double-stranded DNA, virus-like self-synthesizing transposons widely found in eukaryotic genomes. Recent metagenomic discoveries of Polinton-like viruses are consistent with the hypothesis that Polintons invade eukaryotic hos…
View article: DNA polymerase diversity reveals multiple incursions of Polintons during nematode evolution
DNA polymerase diversity reveals multiple incursions of Polintons during nematode evolution Open
Polintons are dsDNA, virus-like self-synthesizing transposons widely found in eukaryotic genomes. Recent metagenomic discoveries of Polinton-like viruses are consistent with the hypothesis that Polintons invade eukaryotic host genomes thro…
View article: Meta-Learning for Better Learning: Using Meta-Learning Methods to Automatically Label Exam Questions with Detailed Learning Objectives
Meta-Learning for Better Learning: Using Meta-Learning Methods to Automatically Label Exam Questions with Detailed Learning Objectives Open
Detailed learning objectives foster an effective and equitable learning environment by clarifying what instructors expect students to learn, rather than requiring students to use prior knowledge to infer these expectations. When questions …
View article: Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study
Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study Open
Purpose The exposure–response relationships for efficacy and safety of ipatasertib, a selective AKT kinase inhibitor, were characterized using data collected from 1101 patients with metastatic castration-resistant prostate cancer in the IP…