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View article: Preprocedural cardiac computed tomography versus transesophageal echocardiography for planning left atrial appendage occlusion procedures
Preprocedural cardiac computed tomography versus transesophageal echocardiography for planning left atrial appendage occlusion procedures Open
The heterogeneous anatomy of the left atrial appendage (LAA) necessitates preprocedural imaging essential for planning of percutaneous LAA occlusion (LAAO) procedures. While transoesophageal echocardiography (TOE) remains the gold standard…
View article: Pre-percutaneous coronary intervention TIMI flow grade in STEMI patients treated with pre-hospital ticagrelor loading
Pre-percutaneous coronary intervention TIMI flow grade in STEMI patients treated with pre-hospital ticagrelor loading Open
Aim We hypothesised that pre-hospital ticagrelor loading would result in a higher proportion of STEMI patients presenting with pre percutaneous coronary intervention TIMI flow grade (ppTFG) 3 than had previously been reported in the clopid…
View article: Candidacy and predicted efficacy of vericiguat in contemporary heart failure outpatient clinics
Candidacy and predicted efficacy of vericiguat in contemporary heart failure outpatient clinics Open
Background Vericiguat is a novel drug class (soluble guanylate cyclase stimulator) approved for the treatment of symptomatic heart failure with reduced ejection fraction (HFrEF) patients who are stable after recent decompensation. Its safe…
View article: 46 Management of non-culprit disease in ST elevation myocardial infarction patients: a three year Irish tertiary referral centre experience
46 Management of non-culprit disease in ST elevation myocardial infarction patients: a three year Irish tertiary referral centre experience Open
Background Recent large scale clinical trials have demonstrated benefit of revascularisation of nonculprit lesions in patients presenting with ST elevation myocardial infarction (STEMI) in terms of reduction in myocardial infarction and ca…
View article: 32 Candidacy and predicted efficacy of vericiguat in contemporary heart failure outpatient clinics
32 Candidacy and predicted efficacy of vericiguat in contemporary heart failure outpatient clinics Open
Background Vericiguat is a novel drug class (soluble guanylate cyclase stimulator) approved for the treatment of symptomatic heart failure with reduced ejection fraction (HFrEF) patients, stable after recent decompensation. Its safety and …
View article: 60 Clinical outcomes in young patients, <45 years old, following acute myocardial infarction, a single centre analysis
60 Clinical outcomes in young patients, <45 years old, following acute myocardial infarction, a single centre analysis Open
Introduction The incidence of acute coronary syndrome in patients under the age of 45 years is low, and subsequently data on medium and long term out comes is lacking. We aimed to assess long term cardiovascular outcomes in patients who pr…
View article: 2 The impact of a conservative management strategy for stable coronary artery disease prior to TAVI
2 The impact of a conservative management strategy for stable coronary artery disease prior to TAVI Open
Background The optimum strategy for managing coronary artery disease (CAD) prior to transcatheter aortic valve implantation (TAVI) remains unclear. A recent consensus statement from the European Association of Percutaneous Cardiovascular I…
View article: 39 3-Year outcomes following 2-stent vs provisional stenting approaches in coronary bifurcation lesions, with analysis of outcomes by lesion complexity as defined by the definition criteria
39 3-Year outcomes following 2-stent vs provisional stenting approaches in coronary bifurcation lesions, with analysis of outcomes by lesion complexity as defined by the definition criteria Open
Introduction ESC guidelines recommend a 2-stent strategy in complex coronary bifurcation lesions, however data on the long-term benefit with a 2-stent strategy is lacking. The definition trial, chen et al JACC 2022, used angiographic crite…
View article: 41 Clinical outcomes and associations with radial to femoral crossover in ST elevation myocardial infarction
41 Clinical outcomes and associations with radial to femoral crossover in ST elevation myocardial infarction Open
Introduction Radial access during primary PCI is associated with reduced mortality and major bleeding when compared to femoral access and is the recommended access site. Nevertheless, failure to secure radial access may necessitate crossov…
View article: 5 Impact of preprocedural computer tomography versus transoesophageal echocardiography for left atrial appendage occlusion procedure planning
5 Impact of preprocedural computer tomography versus transoesophageal echocardiography for left atrial appendage occlusion procedure planning Open
Background The left atrial appendage (LAA) is the central anatomical structure implicated in the pathogenesis of nonvalvular atrial fibrillation related strokes. Where long-term oral anticoagulation is contraindicated, percutaneous transca…
View article: Severe Aortic Valvular Incompetence From IgG4-Related Disease
Severe Aortic Valvular Incompetence From IgG4-Related Disease Open
IgG4-related disease (IgG4-RD) is a new clinical entity characterized by lymphoplasmacytic lesions rich in IgG4-positive plasma cells. Myocardial involvement is extremely rare and not a typical cardiovascular manifestation of IgG4-RD. We r…
View article: Renal Denervation as a Complementary Treatment Option for Uncontrolled Arterial Hypertension: A Situation Assessment
Renal Denervation as a Complementary Treatment Option for Uncontrolled Arterial Hypertension: A Situation Assessment Open
Uncontrolled arterial hypertension is a major global health issue. Catheter-based renal denervation has shown to lower blood pressure in sham-controlled trials and represents a device-based, complementary treatment option for hypertension.…
View article: The Increasing Complexity of Guideline-Directed Medical Therapy for Heart Failure with Reduced Ejection Fraction and Challenges for Real-world Implementation
The Increasing Complexity of Guideline-Directed Medical Therapy for Heart Failure with Reduced Ejection Fraction and Challenges for Real-world Implementation Open
The latest guidelines for heart failure with reduced ejection fraction (HFrEF) recommend concurrent treatment with four drug classes to improve patient outcomes. While physicians likely have the skillsets needed to navigate the complexitie…
View article: AB091. SOH23ABS_221. Pathway to Focused Ultrasound in Intensive Care Heart training at University Hospital Limerick: a 3-year review
AB091. SOH23ABS_221. Pathway to Focused Ultrasound in Intensive Care Heart training at University Hospital Limerick: a 3-year review Open
Background: Basic echocardiography has become a core skill for intensive care medicine trainees. It can provide timely and clinically useful information that can aid intensivists’ decision making and result in changes in patient management…
View article: AB172. SOH23ABS_245. The image management challenges of running a basic cardiac echocardiography training programme
AB172. SOH23ABS_245. The image management challenges of running a basic cardiac echocardiography training programme Open
Background: Basic cardiac echocardiography (ECHO) has become a core skill for intensive care medicine (ICM) trainees. The Joint Faculty of Intensive Care Medicine in Ireland (JFICMI) recognizes the Focused UltraSound in Intensive Care (FUS…
View article: Post‐percutaneous coronary intervention CYP2C19 genotyping in an Irish population: The potential role in identifying clopidogrel therapy‐related bleeding risks
Post‐percutaneous coronary intervention CYP2C19 genotyping in an Irish population: The potential role in identifying clopidogrel therapy‐related bleeding risks Open
Aims Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) remains the standard of care. CYP2C19 genetic polymorphisms cause variable clopidogrel bioactivation. Increased function (CYP2C19*17) allele carriers (rap…
View article: A distinctive posterior mitral valve infective endocarditis and a large mycotic aneurysm
A distinctive posterior mitral valve infective endocarditis and a large mycotic aneurysm Open
A 72-year-old man with a background of hypertension and atrial fibrillation presented with confusion, lumbar back pain and pyrexia. Clinical examination identified a pansystolic murmur radiating to the left axilla. Blood results were signi…
View article: Post-Percutaneous Coronary Intervention CYP2C19 Genotyping: The Potential Role In Identifying Clopidogrel Therapy Related Bleeding Risks
Post-Percutaneous Coronary Intervention CYP2C19 Genotyping: The Potential Role In Identifying Clopidogrel Therapy Related Bleeding Risks Open
Aim Dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) remains the standard of care. CYP2C19 genetic polymorphisms results in variable Clopidogrel bioactivation. Increased function (CYP2C19*17) allele carriers …
View article: SGLT2i uptake among heart failure patients with reduced ejection fraction: ongoing prescriber hesitancy and how to address this
SGLT2i uptake among heart failure patients with reduced ejection fraction: ongoing prescriber hesitancy and how to address this Open
Background The evidence of mortality benefit from sodium-glucose transport protein 2 inhibitors (SGLT2i) in the management of heart failure with reduced ejection fraction (HFrEF) has been observed since 2019. Its first-line use in HFrEF, r…
View article: Peak troponin T in STEMI: a predictor of all-cause mortality and left ventricular function
Peak troponin T in STEMI: a predictor of all-cause mortality and left ventricular function Open
Background The clinical significance of peak troponin levels following ST-elevation myocardial infarction (STEMI) has not been definitively established. The purpose of this study was to examine the relationship between peak high-sensitivit…
View article: Total ischaemic time in STEMI: factors influencing systemic delay
Total ischaemic time in STEMI: factors influencing systemic delay Open
Total ischaemic time in ST-elevation myocardial infarction (STEMI) has been shown to be a predictor of mortality. The aim of this study was to assess the total ischaemic time of STEMIs in an Irish primary percutaneous coronary intervention…
View article: Activation of PPCI team in the octogenarian and nonagenarians population: real-world single-centre experience
Activation of PPCI team in the octogenarian and nonagenarians population: real-world single-centre experience Open
Objective Advancement in healthcare provision has led to increasing octogenarian ST elevation myocardial infarction (STEMI) presentation to hospital for early revascularisation therapies. Limited literature to date exists to suggest octoge…
View article: 60 Is it worth it? The impact of an additional inpatient-dedicated acute cath lab on inpatient time and cost of hospitalization at a national PPCI centre
60 Is it worth it? The impact of an additional inpatient-dedicated acute cath lab on inpatient time and cost of hospitalization at a national PPCI centre Open
Introduction Modern day catheterisation laboratories must cater both for elective outpatient cases and acute inpatient presentations. With the limited resources of our health system under significant strain in the setting of a global pande…
View article: 57 Is intracardiac echo guided left atrial appendage occlusion a safe and cost effective alternative to transoesophageal guided left atrial appendage occlusion? A single centre retrospective review
57 Is intracardiac echo guided left atrial appendage occlusion a safe and cost effective alternative to transoesophageal guided left atrial appendage occlusion? A single centre retrospective review Open
Background Left atrial appendage occlusion (LAAO) can be performed in patients with atrial fibrillation with a contraindication to oral anticoagulation to minimise stroke risk. LAAO is usually performed under transoesophageal echocardiogra…
View article: 24 Shockwave intravascular lithotripsy as an adjunct to percutaneous coronary intervention in calcified coronary lesions: a 2 year, single centre experience
24 Shockwave intravascular lithotripsy as an adjunct to percutaneous coronary intervention in calcified coronary lesions: a 2 year, single centre experience Open
Background Calcified coronary lesions are attributed to multiple risk factors such as increasing age, smoking, DM, and CKD. PCI of calcified lesions is challenging due to impaired stent crossing, under-expansion, and mal-apposition. Shockw…
View article: Multiple systemic paradoxical embolisation of a lower limb deep vein thrombosis due to interatrial septal puncture: a rare complication of left atrial appendage occlusion
Multiple systemic paradoxical embolisation of a lower limb deep vein thrombosis due to interatrial septal puncture: a rare complication of left atrial appendage occlusion Open
A 75-year-old woman with a history of intracranial haemorrhage, atrial fibrillation and coronary artery bypass graft underwent elective left atrial appendage occlusion (LAAO) for stroke prevention. The procedure was successful, however on …
View article: Traumatic right coronary artery dissection
Traumatic right coronary artery dissection Open
A 61-year-old woman presented with two days history of intermittent left-sided chest pain, she is a smoker with a long history of poorly controlled high blood pressure. Clinical examination was remarkable for an ejection systolic murmur in…
View article: 44 Safety and efficacy of ‘same day’ elective coronary angiography and synchronised cardioversion in patients with atrial fibrillation and uninterrupted NOACs
44 Safety and efficacy of ‘same day’ elective coronary angiography and synchronised cardioversion in patients with atrial fibrillation and uninterrupted NOACs Open
Background Synchronised cardioversion is an effective means of restoring sinus rhythm in patients suffering from atrial fibrillation either in acute settings or electively after being commenced on appropriate anticoagulation. Coronary arte…