Sami A. Althwab
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View article: Assessing the impact of intermittent fasting and a low-carbohydrate-high-protein diet on metabolic health and pancreatic histopathology in type 2 diabetic rat model.
Assessing the impact of intermittent fasting and a low-carbohydrate-high-protein diet on metabolic health and pancreatic histopathology in type 2 diabetic rat model. Open
IF with a LCHP diet could be effectively used in improving the indicators of glucose control, and reversing pancreatic histopathological alterations in type 2 diabetes.
View article: Metabolic Effects of Ajwa Date Extract against Gentamicin-Induced Hepatotoxicity and Nephrotoxicity in Male Rats
Metabolic Effects of Ajwa Date Extract against Gentamicin-Induced Hepatotoxicity and Nephrotoxicity in Male Rats Open
This study elaborates on the chemical composition of Ajwa date extract and investigates its different doses against gentamicin (GM)-induced hepatotoxicity and nephrotoxicity in an animal model. GM-administered rats presented various abnorm…
View article: The effect of Ramadan intermittent fasting on anthropometric, hormonal, metabolic, inflammatory, and oxidative stress markers in pre-and post-menopausal women: a prospective cohort of Saudi women
The effect of Ramadan intermittent fasting on anthropometric, hormonal, metabolic, inflammatory, and oxidative stress markers in pre-and post-menopausal women: a prospective cohort of Saudi women Open
Background The menopausal transition significantly affects cardiometabolic health, primarily due to changes in reproductive hormones, particularly decreased estrogen levels and relative androgen excess. Adult Muslim women, both pre-and pos…
View article: Camel Milk Supplemented with Fenugreek Seeds Improve Lipid Profile, Atherogenic Index and Antioxidative Status in Animal Model of Cardiovascular Disorders
Camel Milk Supplemented with Fenugreek Seeds Improve Lipid Profile, Atherogenic Index and Antioxidative Status in Animal Model of Cardiovascular Disorders Open
Pharmacognosy Research,2024,16,3,483-489.DOI:10.5530/pres.16.3.58Published:June 2024Type:Original ArticleAuthors:Sami A. Althwab, Thekra A. Alharby, Waleed Al Abdulmonem, Khalid H. Musa, Zafar Rasheed, Abdullah S. M. Aljohani, Mona S. Almu…
View article: Prediction of cardiovascular risk factors and metabolic syndrome in adults from Saudi Arabia using the logarithm of triglyceride/HDL-cholesterol ratio.
Prediction of cardiovascular risk factors and metabolic syndrome in adults from Saudi Arabia using the logarithm of triglyceride/HDL-cholesterol ratio. Open
Incorporating AIP into clinical practice could enhance CVD risk prediction compared to using lipid profiles alone. These findings suggest that there is a high prevalence of MtS among adults in the Qassim region of Saudi Arabia. Further lon…
View article: Hypolipidemic, Hypoglycemic, and Ameliorative Effects of Boiled Parsley (Petroselinum crispum) and Mallow (Corchorus olitorius) Leaf Extracts in High-Fat Diet-Fed Rats
Hypolipidemic, Hypoglycemic, and Ameliorative Effects of Boiled Parsley (Petroselinum crispum) and Mallow (Corchorus olitorius) Leaf Extracts in High-Fat Diet-Fed Rats Open
Obesity is a major health concern associated with serious conditions such as type 2 diabetes and cardiovascular diseases. This study investigated the potential anti-obesity effects of heat-treated parsley and mallow extracts (PE and ME, re…
View article: Effect of spirulina (Arthrospira platensis) powder addition on nutritional and sensory attributes of chicken mortadella
Effect of spirulina (Arthrospira platensis) powder addition on nutritional and sensory attributes of chicken mortadella Open
The main objective of the present investigation was to evaluate the nutritional and sensory impacts of mortadella supplemented with various levels of Spirulina (Arthrospira platensis) powder (SP). Spirulina powder was investigated for its …
View article: Nutritional and Physicochemical Characteristics of Innovative High Energy and Protein Fruit- and Date-Based Bars
Nutritional and Physicochemical Characteristics of Innovative High Energy and Protein Fruit- and Date-Based Bars Open
With the increasing global nutritional bar market, developing and formulating innovative high-energy and protein bars to compensate for nutrients using date fruits is beneficial for health-conscious individuals. The current research was un…
View article: The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Markers among Premenopausal and Postmenopausal Women: A Cross-Sectional Study
The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Markers among Premenopausal and Postmenopausal Women: A Cross-Sectional Study Open
Background and objectives: Ramadan intermittent fasting (RIF) is a monthlong practice in which Muslims fast during the whole day from sunrise to sunset. During this month, fasting people change their dietary behavior and alter their eating…
View article: The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Biomarkers among Pre-and Post-menopausal Women: A Cross-Sectional Study
The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Biomarkers among Pre-and Post-menopausal Women: A Cross-Sectional Study Open
By shifting eating hours from daytime to nighttime, Ramadan intermittent fasting (RIF) illustrates how religious beliefs influence human dietary behavior and subsequent anthropometric and metabolic measures. This study aimed to investigate…
View article: Regulatory effects of ketogenic diet on the inflammatory response in obese Saudi women
Regulatory effects of ketogenic diet on the inflammatory response in obese Saudi women Open
المخلص: أهداف البحث: في السنوات الأخيرة، اكتسب استخدام النظام الغذائي الكيتوني ضد السمنة شعبية في المملكة العربية السعودية. صممت هذه الدراسة لتحديد تأثير النظام الغذائي الكيتوني على مؤشرات قياس الجسم وعلى التنظيم غير الطبيعي للأنشطة الالته…
View article: Nephroprotective Effect of Fennel (Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats
Nephroprotective Effect of Fennel (Foeniculum vulgare) Seeds and Their Sprouts on CCl4-Induced Nephrotoxicity and Oxidative Stress in Rats Open
Functional and nutritional characteristics of seed sprouts and their association with oxidative stress-related disorders have recently become a focus of scientific investigations. The biological activities of fennel seeds (FS) and fennel s…
View article: Biological Assessment of Stevioside and Sucralose as Sucrose Substitutes for Diabetics on STZ-Induced Diabetes in Rats
Biological Assessment of Stevioside and Sucralose as Sucrose Substitutes for Diabetics on STZ-Induced Diabetes in Rats Open
Numerous food organizations have identified excessive calorie consumption and accompanying ailments as significant health risks associated with high sugar consumption. Administering stevioside (ST), sucralose (SU), and the two synergically…
View article: AMELIORATIVE EFFECT OF FERMENTED GOAT’S MILK COMBINED WITH DESERT TRUFFLE AND BAOBAB AQUEOUS EXTRACT IN CCL4 INDUCED LIVER LESION IN RATS
AMELIORATIVE EFFECT OF FERMENTED GOAT’S MILK COMBINED WITH DESERT TRUFFLE AND BAOBAB AQUEOUS EXTRACT IN CCL4 INDUCED LIVER LESION IN RATS Open
The aim of the present work was to investigate the synergistic hepatoprotective effect of fermented goat milk (FGM) combined with aqueous extracts of baobab (Adansonia digitata L.) (BE) and desert truffle (Terfezia claveryi) (DTE). Chemica…
View article: Nutritional, Physicochemical, and Organoleptic Properties of Camel Meat Burger Incorporating Unpollinated Barhi Date Fruit Pulp
Nutritional, Physicochemical, and Organoleptic Properties of Camel Meat Burger Incorporating Unpollinated Barhi Date Fruit Pulp Open
The chemical composition of unpollinated Barhi date fruit (UBDF) (at khalal maturity stage) pulp and its effect as fiber source or fat replacer on the quality characteristics of camel meat burgers were investigated. The UBDF was characteri…
View article: Fermented camel milk enriched with plant sterols improves lipid profile and atherogenic index in rats fed high -fat and -cholesterol diets
Fermented camel milk enriched with plant sterols improves lipid profile and atherogenic index in rats fed high -fat and -cholesterol diets Open
The current study was designed to explore the effect of fermented camel milk, plant sterols and their combination on the blood levels of sd-LDL and atherogenicity in rats fed on high-fat-cholesterol diets (HFC). Forty male Wistar rats were…
View article: Recognition of Pathogens and Their Inflammatory Signaling Events
Recognition of Pathogens and Their Inflammatory Signaling Events Open
The innate immune system is the main and first line of defense mechanism present in the human body, which acts against a foreign antigen. To function it utilize several mechanisms, among those are the primary one is recognizing the foreign…
View article: Modulation of mice immune responses against Schistosoma mansoni infection with anti-schistosomiasis drugs: Role of interleukin-4 and interferon-gamma.
Modulation of mice immune responses against Schistosoma mansoni infection with anti-schistosomiasis drugs: Role of interleukin-4 and interferon-gamma. Open
These findings indicated that anti-schistosomiasis drugs ART, ARA, and PZQ play a role in the modulation of expression of Th2 cytokines. Whereas, only PZQ may play a role in the modulation of Th1 cytokines. These findings provide a scope f…
View article: Mucormycosis co-infection in COVID-19 patients: An update
Mucormycosis co-infection in COVID-19 patients: An update Open
Mucormycosis (MCM) is a rare fungal disorder that has recently been increased in parallel with novel COVID-19 infection. MCM with COVID-19 is extremely lethal, particularly in immunocompromised individuals. The collection of available scie…
View article: Gastroprotective Effects of Spirulina platensis, Golden Kiwifruit Flesh, and Golden Kiwifruit Peel Extracts Individually or in Combination against Indomethacin-Induced Gastric Ulcer in Rats
Gastroprotective Effects of Spirulina platensis, Golden Kiwifruit Flesh, and Golden Kiwifruit Peel Extracts Individually or in Combination against Indomethacin-Induced Gastric Ulcer in Rats Open
This study was conducted to investigate the therapeutic effect of hydro-alcoholic extract of Spirulina platensis (SP), golden kiwifruit (Actinidia chinensis) flesh (KF), and golden kiwifruit peel (KP) individually or in combination (SFP) o…
View article: ATP2B1 genotypes rs2070759 and rs2681472 polymorphisms and risk of hypertension in Saudi population
ATP2B1 genotypes rs2070759 and rs2681472 polymorphisms and risk of hypertension in Saudi population Open
This study examined an association of ATP2B1 gene polymorphism and hypertension in the Saudi population. The 246 hypertensive cases and 300 healthy human controls were genotyped. The results showed that genotypes rs.207075 (CA + AA) [p = 0…
View article: Protective effect of moringa-based beverages against hyperlipidemia and hyperglycemia in type 2 diabetes-induced rats
Protective effect of moringa-based beverages against hyperlipidemia and hyperglycemia in type 2 diabetes-induced rats Open
The objectives of this study were to determine the phenolic profile and potential antioxidant activity of Moringa oleifera leaves (MOL) cultivated in Saudi Arabia and to investigate the protective effect of moringa-based beverages on lipid…
View article: Polyphenols as promising biologically active substances for preventing SARS-CoV-2: A review with research evidence and underlying mechanisms
Polyphenols as promising biologically active substances for preventing SARS-CoV-2: A review with research evidence and underlying mechanisms Open
View article: Phenolic Profile, Antioxidant Activity, and Ameliorating Efficacy of Chenopodium quinoa Sprouts against CCl4-Induced Oxidative Stress in Rats
Phenolic Profile, Antioxidant Activity, and Ameliorating Efficacy of Chenopodium quinoa Sprouts against CCl4-Induced Oxidative Stress in Rats Open
Quinoa (Chenopodium quinoa) is classified as one of the pseudo-cereal grains rich in both macronutrients and micronutrients. This study tracks changes in the polyphenol composition of red quinoa (RQ) and yellow quinoa (YQ) seeds during ger…
View article: Polyacylated anthocyanins constructively network with catalytic dyad residues of 3CLpro of 2019-nCoV than monomeric anthocyanins: A structural-relationship activity study with 10 anthocyanins using in-silico approaches
Polyacylated anthocyanins constructively network with catalytic dyad residues of 3CLpro of 2019-nCoV than monomeric anthocyanins: A structural-relationship activity study with 10 anthocyanins using in-silico approaches Open
View article: Reduction of Lipid Profile and Adipocyte Size in Rats Fed on High-fat Diet Using Camel Milk and Whey Protein Mixture
Reduction of Lipid Profile and Adipocyte Size in Rats Fed on High-fat Diet Using Camel Milk and Whey Protein Mixture Open
The aim of this study was to examine the effect of oral administration of Camel milk (CM) and whey protein (WP) (1.5 % and 3.0 % in water) - either alone or in a mixture - on obesity parameters and lipid profile in rats fed on a high-fat d…
View article: Protective Effect of Sweet Potato Peel against Oxidative Stress in Hyperlipidemic Albino Rats
Protective Effect of Sweet Potato Peel against Oxidative Stress in Hyperlipidemic Albino Rats Open
In the present investigation, the valorization of sweet potato (Ipomoea batatas L.) wastes into food application with health benefits was studied. Growing interest in the replacement of synthetic food antioxidants by natural ones has foste…