Samia Arifi
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View article: A RARE PRESENTATION OF GASTRIC METASTASIS FROM CLEAR CELL RENAL CARCINOMA
A RARE PRESENTATION OF GASTRIC METASTASIS FROM CLEAR CELL RENAL CARCINOMA Open
Renal cell carcinoma (RCC) is the most prevalent form of kidney cancer and ranks as the 14th most common malignancy worldwide. At the time of diagnosis, around 30% of patients already present with metastatic disease. Bone and visceral meta…
View article: Unexpected Response to Hormonal Therapy in Metastatic Neuroendocrine-Differentiated Prostate Adenocarcinoma: A Case Report
Unexpected Response to Hormonal Therapy in Metastatic Neuroendocrine-Differentiated Prostate Adenocarcinoma: A Case Report Open
Prostate cancer with neuroendocrine differentiation (NEPC) is an aggressive subtype typically considered androgen-indifferent and primarily managed with chemotherapy. Presentation as a hepatic visceral crisis constitutes a medical emergenc…
View article: Survival Outcomes and Prognostic Factors of Metastatic Breast Cancer in Elderly Women: A Retrospective Study in Northeastern Morocco
Survival Outcomes and Prognostic Factors of Metastatic Breast Cancer in Elderly Women: A Retrospective Study in Northeastern Morocco Open
Introduction Breast cancer (BC) is the most common malignancy among women worldwide and the leading cause of cancer-related mortality in women in Morocco. However, there is limited evidence on survival outcomes and treatment patterns among…
View article: SMALL CELL NEUROENDOCRINE CARCINOMA OF THE LARYNX: A RARE AND AGGRESSIVE TUMOR CASE REPORT AND LITERATURE REVIEW
SMALL CELL NEUROENDOCRINE CARCINOMA OF THE LARYNX: A RARE AND AGGRESSIVE TUMOR CASE REPORT AND LITERATURE REVIEW Open
Introduction: Small cell neuroendocrine carcinomas (SCNECs) of the larynx are extremely rare, representing approximately 0.6% of all laryngeal malignancies. They follow an aggressive clinical course and are a sociated with a poor prognosis…
View article: ENDOMETRIAL METASTASIS OF BREAST CANCER: A CASE REPORT AND REVIEW OF THE LITERATURE
ENDOMETRIAL METASTASIS OF BREAST CANCER: A CASE REPORT AND REVIEW OF THE LITERATURE Open
Endometrial metastasis of breast cancer is an exceptionally rare occurrence, with limited cases reported in the literature. While breast cancer commonly metastasizes to bones, lungs, liver, and brain, endometrial involvement remains unusua…
View article: PROGNOSIS OF TESTICULAR GERM CELL TUMORS: EXPERIENCE FROM THE MEDICAL ONCOLOGY DEPARTMENT OF HASSAN II HOSPITAL IN FEZ AND A REVIEW OF THE LITERATURE
PROGNOSIS OF TESTICULAR GERM CELL TUMORS: EXPERIENCE FROM THE MEDICAL ONCOLOGY DEPARTMENT OF HASSAN II HOSPITAL IN FEZ AND A REVIEW OF THE LITERATURE Open
Introduction: Testicular germ cell tumors (TGCTs) account for 98% of malignant testicular tumors and are the most common solid malignancies in men aged between 15 and 35 years. This study describes the prognosis and management of 48 patien…
View article: Small Cell Neuroendocrine Carcinoma of Bartholin\\\'s Gland: A Case Report
Small Cell Neuroendocrine Carcinoma of Bartholin\\\'s Gland: A Case Report Open
Small cell carcinoma (SCC) is a rare tumor predominantly found in the lungs, with only 5% occurring outside the pulmonary system. Despite its common occurrence in the cervix, SCC can also develop in the ovaries, endometrium, vagina, …
View article: Is the gemcitabin-cisplatin combination the optimal induction chemotherapy for non-Asian patients with nasopharyngeal carcinoma (NPC)? Insights from a cohort in north-eastern Morocco
Is the gemcitabin-cisplatin combination the optimal induction chemotherapy for non-Asian patients with nasopharyngeal carcinoma (NPC)? Insights from a cohort in north-eastern Morocco Open
In patients with locally advanced NPC, DP-based IC demonstrated superior ORR compared with the GC regimen, with acceptable toxicity. Further studies are required to validate these results.
View article: Current Situation and Management of Pleural Effusion in PHI Clinical Hospital Tetovo
Current Situation and Management of Pleural Effusion in PHI Clinical Hospital Tetovo Open
Introduction: Pleural effusion is a disturbance in the balance between fluid production and elimination in the pleural space, resulting in abnormal fluid accumulation. It can result from various medical conditions related to the lungs and …
View article: Total Neoadjuvant Treatment in Locally Advanced Rectal Cancer: A Comparative Study of PRODIGE 23 versus RAPIDO Protocols
Total Neoadjuvant Treatment in Locally Advanced Rectal Cancer: A Comparative Study of PRODIGE 23 versus RAPIDO Protocols Open
View article: Metastatic Renal Medullary Carcinoma: Case Report and Review of the Literature
Metastatic Renal Medullary Carcinoma: Case Report and Review of the Literature Open
View article: Breast Metastases of Rectal Cancer: A Case Report and Review of the Literature
Breast Metastases of Rectal Cancer: A Case Report and Review of the Literature Open
View article: Impact of the COVID-19 Pandemic on Cancer Patients: Experience of the medical oncology department of CHU HASSAN II Fez.
Impact of the COVID-19 Pandemic on Cancer Patients: Experience of the medical oncology department of CHU HASSAN II Fez. Open
Introduction: In December 2019, COVID 19 spread worldwide, but did not officially start in MOROCCO until March 02, 2020. Since then, this pandemic has significantly impacted the health status of patients in general and cancer patients in p…
View article: Descriptive Study of Localized Pancreas Cancers: Experience of CHU Hassan II of Fes
Descriptive Study of Localized Pancreas Cancers: Experience of CHU Hassan II of Fes Open
Pancreatic cancer is on the rise, ranking 13th among cancer sites in the world and 5th among digestive cancers.Real-life national data on patients with localized pancreatic adenocarcinoma are lacking in the medical literature given their n…
View article: Embryonal Rhabdomyosarcoma of the Bladder in Adults: A Case Report and Comprehensive Literature Review
Embryonal Rhabdomyosarcoma of the Bladder in Adults: A Case Report and Comprehensive Literature Review Open
This article discusses a rare case of embryonal rhabdomyosarcoma (RMS) in a 32-year-old adult with a history of chronic smoking.The patient presented symptoms of dysuria and frequent urination, leading to the discovery of a low-grade RMS i…
View article: Actual Data on the Efficacy and Safety of Gemcitabine-Docetaxel as Second-Line and Beyond Treatment in Adult Patients with Metastatic Bone Sarcomas: Experience from a Single Institution
Actual Data on the Efficacy and Safety of Gemcitabine-Docetaxel as Second-Line and Beyond Treatment in Adult Patients with Metastatic Bone Sarcomas: Experience from a Single Institution Open
Osteosarcoma, the most prevalent primary malignant bone tumor in children, presents significant challenges in treatment, particularly in cases of recurrence or refractory disease.This retrospective study explores the efficacy and safety of…
View article: Real-life Results of a Cohort of Retroperitoneal Sarcomas (RPS): Management at Hassan II University Hospital in Fes
Real-life Results of a Cohort of Retroperitoneal Sarcomas (RPS): Management at Hassan II University Hospital in Fes Open
Retroperitoneal sarcomas (RPS) pose a challenge in treatment due to their rarity and complex nature.This retrospective study aimed to analyze the epidemiological, clinicopathological characteristics, and survival outcomes of RPS patients t…
View article: MYOCARDIAL INFARCTION UNDER METHOTREXATE IN A PATIENT WITH LOW RISK GESTATIONAL TROPHO BLASTIC NEOPLASIA: A CASE REPORT
MYOCARDIAL INFARCTION UNDER METHOTREXATE IN A PATIENT WITH LOW RISK GESTATIONAL TROPHO BLASTIC NEOPLASIA: A CASE REPORT Open
Background: Methotrexate, an antifolateantimetabolite, finds extensive application in the field of oncology as well as for managingvariousautoimmunediseases. It isconsidered as backbone treatment for bothlow and high risk, trophoblasticges…
View article: MYOCARDIAL INFARCTION UNDER METHOTREXATE IN A PATIENT WITH LOW RISK GESTATIONAL TROPHO BLASTIC NEOPLASIA: A CASE REPORT
MYOCARDIAL INFARCTION UNDER METHOTREXATE IN A PATIENT WITH LOW RISK GESTATIONAL TROPHO BLASTIC NEOPLASIA: A CASE REPORT Open
Background: Methotrexate, an antifolateantimetabolite, finds extensive application in the field of oncology as well as for managingvariousautoimmunediseases. It isconsidered as backbone treatment for bothlow and high risk,…
View article: MUCOEPIDERMOIDCARCINOMA OF THE PANCREAS: A CASE REPORT
MUCOEPIDERMOIDCARCINOMA OF THE PANCREAS: A CASE REPORT Open
Mucoepidermoidcarcinoma (MEC) is a rare neoplasmthat arises from the exocrine glands and iscommonlyfound in the salivary glands. However, MEC of the pancreasis an exceedingly rare entity, withonly a few documented cases in the literature. …
View article: Editorial: Precision medicine in sarcomas: the road to an effective biomarker-driven-care strategy
Editorial: Precision medicine in sarcomas: the road to an effective biomarker-driven-care strategy Open
EDITORIAL article Front. Oncol., 05 April 2023Sec. Molecular and Cellular Oncology Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1194593
View article: Exploring the landscape of immunotherapy approaches in sarcomas
Exploring the landscape of immunotherapy approaches in sarcomas Open
Sarcomas comprise a heterogenous group of malignancies, of more than 100 different entities, arising from mesenchymal tissue, and accounting for 1% of adult malignancies. Surgery, radiotherapy and systemic therapy constitute the therapeuti…
View article: Soft Tissue Sarcomas: Descriptive Study of 232 Cases Collected, over a Period of 10 Years, at the Hospital of Oncology, Department of the Hassan II Hospital FEZ
Soft Tissue Sarcomas: Descriptive Study of 232 Cases Collected, over a Period of 10 Years, at the Hospital of Oncology, Department of the Hassan II Hospital FEZ Open
Soft-tissue sarcomas are uncommon tumors that have traditionally been managed by wide excisional surgery and radiotherapy; the use of chemotherapy has been reserved for advanced disease. Advances in multidisciplinary care have improved the…
View article: Primary Extra-Gastrointestinal Stromal Tumors (E-GIST) of the Liver, about Two Cases and Review of the Literature Oncology Hospital Experience at Chu Hassan II in FES
Primary Extra-Gastrointestinal Stromal Tumors (E-GIST) of the Liver, about Two Cases and Review of the Literature Oncology Hospital Experience at Chu Hassan II in FES Open
Introduction: Primary extra-gastrointestinal stromal tumors (E-GIST) of the liver are rare. The clinical presentation can range from asymptomatic to bleeding or manifestations of mass effect. Cancer surgery followed by adjuvant treatment w…
View article: Comparison of Clinicopathological and Survival Features of Right and Left Colon Cancers: Experience of the Medical Oncology Department of Fez
Comparison of Clinicopathological and Survival Features of Right and Left Colon Cancers: Experience of the Medical Oncology Department of Fez Open
Right-sided colon cancers (RCC) and left-sided colon cancers (LCC) have different epidemiological, physiological, pathological, genetic, and clinical characteristics, which result in differences in the course, prognosis, and outcome of dis…
View article: Mediastinal NUT carcinoma: about a case report including immunotherapy in therapeutic management
Mediastinal NUT carcinoma: about a case report including immunotherapy in therapeutic management Open
NUT carcinoma (NC), also known as NUT midline carcinoma, is a rare, genetically defined and highly lethal undifferentiated carcinoma occurring in the midline location of the neck, head or mediastinum. We present the case of a 36-year-old C…
View article: Long term disease control under aromatase inhibitor for advanced low grade stromal endometrial carcinoma: Case Repot from a tertiary care hospital in Morocco.
Long term disease control under aromatase inhibitor for advanced low grade stromal endometrial carcinoma: Case Repot from a tertiary care hospital in Morocco. Open
Low-grade stromal endometrial sarcoma (ESS) is a rare type of uterine cancer that arises from the stromal cells of the endometrium, which is the inner lining of the uterus. It is a subtype of endometrial stromal sarcoma, which is a group o…
View article: Pre-Sacral Chordomas, about Two Cases and Review of the Literature
Pre-Sacral Chordomas, about Two Cases and Review of the Literature Open
The World Health Organization (WHO) defines chordoma as a malignant tumor of intermediate or low grade, developing at the expense of embryonic remnants of the notochord. These tumors represent 8.4% of all malignant bone tumors. We report 2…
View article: Efficacy of Bevacizumab versus Epidermal Growth Factor Receptor Inhibitors for Ras Wild Type Metastatic Colorectal Cancer: A Real-World Data Analysis from a Tertiary Care Institution
Efficacy of Bevacizumab versus Epidermal Growth Factor Receptor Inhibitors for Ras Wild Type Metastatic Colorectal Cancer: A Real-World Data Analysis from a Tertiary Care Institution Open
Introduction: A combination of chemotherapy regimen and biologics in patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) resulted in improvements in survival.However, the optimal choice of initial biologic therapy in previ…
View article: Molecular classification of soft tissue sarcomas for adequate diagnosis: A study on the northeast population of Morocco
Molecular classification of soft tissue sarcomas for adequate diagnosis: A study on the northeast population of Morocco Open
This is the first and the largest Moroccan series for the molecular diagnosis of STS by FISH. Our study shows that paraffin FISH is a sensitive and specific ancillary tool in the diagnosis of STS when used in the appropriate clinicopatholo…