S.M. Arif
YOU?
Author Swipe
View article: Cavernous sinus hemangiomas: stereotactic radiosurgery as gold standard, with robotics and AI on the horizon
Cavernous sinus hemangiomas: stereotactic radiosurgery as gold standard, with robotics and AI on the horizon Open
Cavernous sinus hemangiomas (CSHs) are rare, highly vascular tumors of the skull base where conventional surgery carries substantial morbidity. Stereotactic radiosurgery (SRS) has emerged as the gold standard, offering >90% local control a…
View article: Role of Zinc Supplementation in Treating Acute Respiratory Infection in Children Under 5 Years of Age
Role of Zinc Supplementation in Treating Acute Respiratory Infection in Children Under 5 Years of Age Open
Objective: To compare the efficacy of added zinc supplementation to standard treatment in improving the course of acute respiratory infections (ARI) when compared with standard treatment alone in children under 5 years of age Study Design:…
View article: Predictors Of Antepartum Hemorrhage In Patients With Placenta Previa
Predictors Of Antepartum Hemorrhage In Patients With Placenta Previa Open
Antepartum Hemorrhage (APH) is a significant complication in pregnancy that poses serious risks to both maternal and fetal health. Objective: To find the predictors of antepartum hemorrhage in patients with placenta previa among the local …
View article: The Effect of Leg Muscle Strength Training in Reducing Knee Pain Intensity among Elderly Women
The Effect of Leg Muscle Strength Training in Reducing Knee Pain Intensity among Elderly Women Open
Aging naturally reduces physiology, increasing susceptibility to injuries, particularly in the knee joint, which supports substantial body weight and is vulnerable to osteoarthritis and ligament injuries. The current study investigates the…
View article: Adult outcomes of complex pulmonary atresia, ventricular septal defect and major aortopulmonary collaterals following repair during childhood, a single centre experience
Adult outcomes of complex pulmonary atresia, ventricular septal defect and major aortopulmonary collaterals following repair during childhood, a single centre experience Open
Background Complex pulmonary atresia with a ventricular septal defect and major aortopulmonary collateral arteries (PA VSD MAPCA) is a rare and complex form of congenital heart disease. Staged surgical palliation is carried out in childhoo…
View article: Using Structure-guided Fragment-Based Drug Discovery to Target Pseudomonas aeruginosa Infections in Cystic Fibrosis
Using Structure-guided Fragment-Based Drug Discovery to Target Pseudomonas aeruginosa Infections in Cystic Fibrosis Open
Cystic fibrosis (CF) is progressive genetic disease that predisposes lungs and other organs to multiple long-lasting microbial infections. Pseudomonas aeruginosa is the most prevalent and deadly pathogen among these microbes. Lung function…
View article: COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets
COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets Open
Mutations in hallmark genes are believed to be the main drivers of cancer progression. These mutations are reported in the Catalogue of Somatic Mutations in Cancer (COSMIC). Structural appreciation of where these mutations appear, in prote…
View article: Follow up after atrial switch surgery in patients with transposition of the great arteries; reality versus guidelines
Follow up after atrial switch surgery in patients with transposition of the great arteries; reality versus guidelines Open
Introduction: Atrial switch surgery, previously the intervention of choice for transposition of the great arteries, has been superseded by the arterial switch operation. The cohorts of patients who received atrial switch operations remain …
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1
Plasticity, ligand conformation and enzyme action of Mycobacterium smegmatis MutT1 Open
Mycobacterium smegmatis MutT1 (MsMutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-ox…
View article: Plasticity, ligand conformation and enzyme action of <i>Mycobacterium smegmatis</i> MutT1
Plasticity, ligand conformation and enzyme action of <i>Mycobacterium smegmatis</i> MutT1 Open
Mycobacterium smegmatis MutT1 ( Ms MutT1) is a sanitation enzyme made up of an N-terminal Nudix hydrolase domain and a C-terminal domain resembling a histidine phosphatase. It has been established that the action of MutT1 on 8-oxo-dGTP, 8-…
View article: Structural studies on <i>M. smegmatis</i> MutT2, a sanitization enzyme
Structural studies on <i>M. smegmatis</i> MutT2, a sanitization enzyme Open
Incorporation in DNA of oxidized or damaged nucleotides, such as 8-oxo-dGTP or 5-me-dCTP generated during cellular metabolism or as a response to stress in the host cell, is detrimental to genomic integrity.Apart from a plethora of DNA rep…