Samin Alavi
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View article: Urothelial Papilloma of the Urinary Bladder in a Child
Urothelial Papilloma of the Urinary Bladder in a Child Open
Urothelial papilloma (UP) of the bladder is an extremely rare benign neoplasm in pediatrics, often manifested as gross hematuria. These lesions are typically small, well‐circumscribed, located on the lateral or posterior bladder wall, freq…
View article: When the unexpected strikes: hepatocellular carcinoma in a teen with ataxia-telangiectasia
When the unexpected strikes: hepatocellular carcinoma in a teen with ataxia-telangiectasia Open
Background: Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder characterized by progressive cerebellar ataxia, oculocutaneous telangiectasia, and profound immunodeficiency. Although individuals with A-T exhibit a heightened…
View article: A Report on the Clinical Efficacy of Rituximab Administration in Patients with Inborn Errors of Immunity and Autoimmune/Autoinflammatory Manifestations
A Report on the Clinical Efficacy of Rituximab Administration in Patients with Inborn Errors of Immunity and Autoimmune/Autoinflammatory Manifestations Open
It can sometimes be very difficult to control the manifestations of autoimmunity and lymphoproliferation in patients with primary immunodeficiency diseases, and there is no adequate response to first-line treatments. Rituximab (RTX), as a …
View article: Congenital self-healing Langerhans cell histiocytosis vs benign cephalic histiocytosis: A comprehensive literature review of pediatric cutaneous histiocytoses
Congenital self-healing Langerhans cell histiocytosis vs benign cephalic histiocytosis: A comprehensive literature review of pediatric cutaneous histiocytoses Open
View article: Creating a National Pediatric Thrombosis Registry: a cohort prospective study by the Iranian Society of Thrombosis and Hemostasis
Creating a National Pediatric Thrombosis Registry: a cohort prospective study by the Iranian Society of Thrombosis and Hemostasis Open
Background: Venous thromboembolism (VTE) in pediatric populations, though historically rare, is increasingly recognized due to improved diagnostic methods and heightened clinical awareness. Pediatric VTE presents distinct epidemiological p…
View article: A randomized, two-armed, double-blind, single-dose, cross-over, bioequivalence clinical trial to compare pharmacokinetic parameters and safety of recombinant human factor VIII with Fc fusion produced by AryoGen Pharmed Company versus Elocta® (reference product) in previously treated patients with severe haemophilia A
A randomized, two-armed, double-blind, single-dose, cross-over, bioequivalence clinical trial to compare pharmacokinetic parameters and safety of recombinant human factor VIII with Fc fusion produced by AryoGen Pharmed Company versus Elocta® (reference product) in previously treated patients with severe haemophilia A Open
This clinical study evaluates the bioequivalence of recombinant factor VIII with Fc fusion protein (rFVIII-Fc) developed by AryoGen Pharmed Company compared to the reference product, Elocta® by Sobi Co., in severe haemophilia A …
View article: Therapeutic Innovation in Pediatric Neuroblastoma: Age and Stage-Specific Strategies from Prenatal to Early Childhood-A Review Article.
Therapeutic Innovation in Pediatric Neuroblastoma: Age and Stage-Specific Strategies from Prenatal to Early Childhood-A Review Article. Open
Neuroblastoma is one of the most common pediatric cancers, predominantly affecting young children. Despite progress in initial treatments, high-risk cases remain challenging due to frequent relapse or resistance, with long-term survival fo…
View article: Three Challenges in an Infant: Neuroblastoma Mimicking Infantile Hepatic Hemangioma, With Chylothorax and Rosettes in Pleural Fluid
Three Challenges in an Infant: Neuroblastoma Mimicking Infantile Hepatic Hemangioma, With Chylothorax and Rosettes in Pleural Fluid Open
Infantile hepatic hemangioma (IHH) is rare, but the most common benign hepatic tumor in the first year of life. It has a characteristic course with perinatal presentation, increasing growth during the first year of life, and subsequent shr…
View article: Clinical Characteristics and Outcomes of COVID-19 in Pediatric Cancer Patients: A Retrospective Cohort Study
Clinical Characteristics and Outcomes of COVID-19 in Pediatric Cancer Patients: A Retrospective Cohort Study Open
Background: The impact of COVID-19 on pediatric cancer patients remains a critical area of investigation. Objectives: This study aimed to compare the clinical characteristics and outcomes of COVID-19 in children with and without malignanci…
View article: Mechanical thrombectomy by stent retriever for the treatment of arterial ischemic stroke in a pediatric patient with acute lymphoblastic leukemia: a case report
Mechanical thrombectomy by stent retriever for the treatment of arterial ischemic stroke in a pediatric patient with acute lymphoblastic leukemia: a case report Open
Introduction: Arterial ischemic stroke (AIS) caused by occlusion of large vessels in childhood is a devastating rare condition that can contribute to long-term disabilities. Childhood leukemia is identified as a recognized risk factor for …
View article: Arterial stroke in a child with Seckel syndrome with a pattern of non‐moyamoya vasculopathy
Arterial stroke in a child with Seckel syndrome with a pattern of non‐moyamoya vasculopathy Open
Key Clinical Message Seckel syndrome is a rare autosomal recessive disorder, characterized by growth retardation and multiple anomalies associated with CNS vasculopathy. We describe a child with Seckel syndrome who developed a stroke due t…
View article: Moyamoya Disease in a Child With Fanconi Anemia: An Anomaly or a Complication
Moyamoya Disease in a Child With Fanconi Anemia: An Anomaly or a Complication Open
Fanconi anemia (FA) is an inherited bone marrow failure syndrome associated with congenital anomalies and a predisposition to cancer. We report the case of a 9-year-old boy with FA who developed an abrupt onset of hemiplegia and dysarthria…
View article: RETRACTED: Establishment of Iranian Pediatric Thrombosis Registry (IPTR) by Iranian Society of Thrombosis and Hemostasis (IRSTH): A Preliminary Report
RETRACTED: Establishment of Iranian Pediatric Thrombosis Registry (IPTR) by Iranian Society of Thrombosis and Hemostasis (IRSTH): A Preliminary Report Open
The authors have requested that this preprint be removed from Research Square.
View article: Extraskeletal conventional chondrosarcoma of genitalia in a child- An unusual pathology for a rare tumor
Extraskeletal conventional chondrosarcoma of genitalia in a child- An unusual pathology for a rare tumor Open
We present a unique case of extraskeletal chondrosarcoma in a child with conventional subtype which has not been reported in the literature. In addition, the lesion was assumed to arise from a previous soft tissue enchondroma of the labia …
View article: PB0281 Establishment of a National Patient-Based Pediatric Thrombosis Registry by Iranian Society of Thrombosis and Hemostasis
PB0281 Establishment of a National Patient-Based Pediatric Thrombosis Registry by Iranian Society of Thrombosis and Hemostasis Open
View article: The Iranian Childhood Cancer Biobank
The Iranian Childhood Cancer Biobank Open
View article: Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry
Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation diseases: Middle East and North Africa registry Open
View article: Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine
Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine Open
Kaposiform Hemangioendothelioma of Abdominal Wall Associated with Kasabach-Merritt in A Newborn with Dramatic Response to Sirolimus and Vincristine
View article: Osteopetrosis Presenting with Neonatal Thrombocytopenia: A Case Report
Osteopetrosis Presenting with Neonatal Thrombocytopenia: A Case Report Open
Background: Osteopetrosisis an inherited and rare bone disease, characterized by the impairment ofbone modeling and remodeling and the failure of osteoclasts to resorb bone. It also results in skeletal fragility despite increased bone mass…
View article: ecancermedicalscience
ecancermedicalscience Open
Adrenocortical tumour is rare in children. We report on a female infant with adrenocortical carcinoma presenting with pseudoprecocious puberty at the age of two. She had a history of gradually increasing public hair growth after birth. Phy…
View article: ecancermedicalscience
ecancermedicalscience Open
Clear cell sarcoma of the kidney (CCSK) is a rare renal neoplasm of paediatrics, making up about 3% of all renal tumours in paediatrics, with a high tendency for developing bone metastasis. A seven year-old boy was referred to our clinic w…
View article: Secondary ALL after Successful Treatment of Ewing's Sarcoma: A Case Report.
Secondary ALL after Successful Treatment of Ewing's Sarcoma: A Case Report. Open
Treatment with intensification of chemotherapy using alkylating agents and Topoisomerase II inhibitors and radiotherapy has improved the outcome of patients with solid tumors such as Ewing's sarcoma. However, there are several reports of s…
View article: Congenital Pleomorphic Adenoma in a SubmandibularGland of a Newborn- A Case Report.
Congenital Pleomorphic Adenoma in a SubmandibularGland of a Newborn- A Case Report. Open
Congenital pleomorphic adenoma rarely occurs in the nasopharynx and is treated by surgical excision. Our case is unique because the congenital pleomorphic adenoma is located in the submandibular gland of a newborn.
View article: Hereditary Spherocytosis Unmasked by Human Parvovirus B19 Induced Aplastic Crisis in a Family.
Hereditary Spherocytosis Unmasked by Human Parvovirus B19 Induced Aplastic Crisis in a Family. Open
Human parvovirus (HPV) B19 induced aplastic crisis in a family leading to the diagnosis of hereditary spherocytosis (HS) is a very rare condition being barely reported in the literature. We herein report a 4-year-old girl, her brother, and…
View article: Pyoderma Vegetans: A Case Report in a Child Suspected to Primary Immunodeficiency and Review of the Literature.
Pyoderma Vegetans: A Case Report in a Child Suspected to Primary Immunodeficiency and Review of the Literature. Open
Pyoderma vegetans (PV) is a rare inflammatory disorder characterized by vegetating pustules and plaques affecting the skin and mucosal membranes. It is believed that this entity is mostly associated with inflammatory bowel disease (IBD), c…
View article: A 6 Year-old Male Presented With Difficulty in Passing Urine and Poor Urine Stream
A 6 Year-old Male Presented With Difficulty in Passing Urine and Poor Urine Stream Open
View article: Primary Ewing's Sarcoma of the temporal bone in an infant.
Primary Ewing's Sarcoma of the temporal bone in an infant. Open
Introduction : Ewing's sarcoma is the second most common primary malignant tumor of bone found in children after Osteosarcoma. It accounts for 4-9% of primary malignant bone tumors and it affects bones of the skull or face in only 1-4% of …