Samuel D. Kaffenberger
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View article: Prolonged Progression-Free Survival, Disease-Free Survival, and Cystectomy Avoidance With IL-15 Receptor Lymphocyte–Stimulating Agent NAI Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin–Unresponsive Papillary-Only Nonmuscle-Invasive Bladder Cancer
Prolonged Progression-Free Survival, Disease-Free Survival, and Cystectomy Avoidance With IL-15 Receptor Lymphocyte–Stimulating Agent NAI Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin–Unresponsive Papillary-Only Nonmuscle-Invasive Bladder Cancer Open
ClinicalTrials.gov Identifier: NCT03022825.
View article: Spatial Heterogeneity of Glomerular Phenotypes Affects Kidney Biopsy Findings
Spatial Heterogeneity of Glomerular Phenotypes Affects Kidney Biopsy Findings Open
Key Points Glomeruli with pathologic changes are not homogeneously distributed throughout the kidney cortex. Biopsies that do not include the kidney capsule may underdetect glomeruli with pathologic changes. Location of glomeruli with path…
View article: Comparing Patient-reported Functional Outcomes After Radical Prostatectomy in Historical and Contemporary Practice
Comparing Patient-reported Functional Outcomes After Radical Prostatectomy in Historical and Contemporary Practice Open
Our results demonstrate that the widespread alterations in prostate cancer surgery over the past 2 decades have yielded improvements in sexual, but not urinary, function recovery.
View article: A Phase I Trial of Neoadjuvant Stereotactic Body Radiotherapy (SBRT) Prior to Radical Prostatectomy (RP) in Locally Advanced Prostate Cancer
A Phase I Trial of Neoadjuvant Stereotactic Body Radiotherapy (SBRT) Prior to Radical Prostatectomy (RP) in Locally Advanced Prostate Cancer Open
View article: Prostate cancer clinical trial completion: The role of geography
Prostate cancer clinical trial completion: The role of geography Open
View article: PD08-02 NEOADJUVANT STEREOTACTIC BODY RADIOTHERAPY (SBRT) PRIOR TO RADICAL PROSTATECTOMY (RP) IN LOCALLY ADVANCED PROSTATE CANCER: A PHASE I TRIAL
PD08-02 NEOADJUVANT STEREOTACTIC BODY RADIOTHERAPY (SBRT) PRIOR TO RADICAL PROSTATECTOMY (RP) IN LOCALLY ADVANCED PROSTATE CANCER: A PHASE I TRIAL Open
You have accessJournal of UrologyProstate Cancer: Localized: Radiation Therapy (PD08)1 Sep 2021PD08-02 NEOADJUVANT STEREOTACTIC BODY RADIOTHERAPY (SBRT) PRIOR TO RADICAL PROSTATECTOMY (RP) IN LOCALLY ADVANCED PROSTATE CANCER: A PHASE I TRI…
View article: MP24-02 SATISFACTION WITH CLINICIAN-LED GERMLINE GENETIC COUNSELING IN MEN WITH PROSTATE CANCER
MP24-02 SATISFACTION WITH CLINICIAN-LED GERMLINE GENETIC COUNSELING IN MEN WITH PROSTATE CANCER Open
You have accessJournal of UrologyProstate Cancer: Advanced (including Drug Therapy) II (MP24)1 Sep 2021MP24-02 SATISFACTION WITH CLINICIAN-LED GERMLINE GENETIC COUNSELING IN MEN WITH PROSTATE CANCER Marissa A. Solorzano, Randy Vince, Mallo…
View article: MP19-06 MISMATCHES IN TRIAL LOCATION AND PROSTATE CANCER INCIDENCE: TIME TO BRING THE TRIALS TO THE PATIENTS?
MP19-06 MISMATCHES IN TRIAL LOCATION AND PROSTATE CANCER INCIDENCE: TIME TO BRING THE TRIALS TO THE PATIENTS? Open
You have accessJournal of UrologyHealth Services Research: Practice Patterns, Quality of Life and Shared Decision Making II (MP19)1 Sep 2021MP19-06 MISMATCHES IN TRIAL LOCATION AND PROSTATE CANCER INCIDENCE: TIME TO BRING THE TRIALS TO THE…
View article: Reply by Authors
Reply by Authors Open
No AccessUrology PracticeBusiness of Urology1 Mar 2021Reply by Authorsis a reply to letterEditorial CommentEditorial Comment Juan J. Andino, Michael Sessine, Udit Singhal, Zachery R. Reichert, Daniel Wray, Christine Shafer, Marissa Moore, …
View article: Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to Neoadjuvant ADT: An Individual Patient Meta-Analysis
Prostate Radiotherapy With Adjuvant Androgen Deprivation Therapy (ADT) Improves Metastasis-Free Survival Compared to Neoadjuvant ADT: An Individual Patient Meta-Analysis Open
PURPOSE There remains a lack of clarity regarding the influence of sequencing of androgen deprivation therapy (ADT) and radiotherapy (RT) on outcomes in prostate cancer (PCa). Herein, we evaluate the optimal sequencing of ADT with prostate…
View article: Estimating the rate and reasons of clinical trial failure in urologic oncology
Estimating the rate and reasons of clinical trial failure in urologic oncology Open
View article: Development and Validation of a Clinical Prognostic Stage Group System for Nonmetastatic Prostate Cancer Using Disease-Specific Mortality Results From the International Staging Collaboration for Cancer of the Prostate
Development and Validation of a Clinical Prognostic Stage Group System for Nonmetastatic Prostate Cancer Using Disease-Specific Mortality Results From the International Staging Collaboration for Cancer of the Prostate Open
Using a large, diverse international cohort treated with standard curative treatment options, a proposed AJCC-compliant clinical prognostic stage group system for prostate cancer has been developed. This system may allow consistency of rep…
View article: Understanding the Barriers to Neoadjuvant Chemotherapy in Patients with Muscle Invasive Bladder Cancer: A Quality Improvement Initiative
Understanding the Barriers to Neoadjuvant Chemotherapy in Patients with Muscle Invasive Bladder Cancer: A Quality Improvement Initiative Open
Despite the relatively high rates of medical oncology referral and NAC use in this cohort, there are still opportunities to improve the efficiency of this practice. Quality improvement initiatives could optimize the referral of patients wi…
View article: Assessing Genitourinary Cancer Clinical Trial Accrual Sufficiency Using Archived Trial Data
Assessing Genitourinary Cancer Clinical Trial Accrual Sufficiency Using Archived Trial Data Open
PURPOSE Clinical trials often fail to reach their anticipated end points, most frequently because of poor accrual. Prior studies have analyzed trial termination, but it has not been easy to assess accrual estimates using international data…
View article: Addition of Androgen-Deprivation Therapy or Brachytherapy Boost to External Beam Radiotherapy for Localized Prostate Cancer: A Network Meta-Analysis of Randomized Trials
Addition of Androgen-Deprivation Therapy or Brachytherapy Boost to External Beam Radiotherapy for Localized Prostate Cancer: A Network Meta-Analysis of Randomized Trials Open
PURPOSE In men with localized prostate cancer, the addition of androgen-deprivation therapy (ADT) or a brachytherapy boost (BT) to external beam radiotherapy (EBRT) have been shown to improve various oncologic end points. Practice patterns…
View article: PD48-06 DETECTION OF GERMLINE MUTATIONS IN LOCALIZED AND METASTATIC PROSTATE CANCER THROUGH GUIDLINE-BASED TESTING
PD48-06 DETECTION OF GERMLINE MUTATIONS IN LOCALIZED AND METASTATIC PROSTATE CANCER THROUGH GUIDLINE-BASED TESTING Open
You have accessJournal of UrologyProstate Cancer: Detection & Screening V (PD48)1 Apr 2020PD48-06 DETECTION OF GERMLINE MUTATIONS IN LOCALIZED AND METASTATIC PROSTATE CANCER THROUGH GUIDLINE-BASED TESTING Randy Vince*, Jake Quarles, Michel…
View article: PD47-11 RAPID ORGANOID DEVELOPMENT, DRUG SCREENING, AND NEOADJUVANT CHEMOTHERAPY RESPONSE PREDICTION FOR PATIENTS WITH LOCALLY-ADVANCED BLADDER CANCER
PD47-11 RAPID ORGANOID DEVELOPMENT, DRUG SCREENING, AND NEOADJUVANT CHEMOTHERAPY RESPONSE PREDICTION FOR PATIENTS WITH LOCALLY-ADVANCED BLADDER CANCER Open
You have accessJournal of UrologyBladder Cancer: Basic Research & Pathophysiology IV (PD47)1 Apr 2020PD47-11 RAPID ORGANOID DEVELOPMENT, DRUG SCREENING, AND NEOADJUVANT CHEMOTHERAPY RESPONSE PREDICTION FOR PATIENTS WITH LOCALLY-ADVANCED BL…
View article: Performance of clinicopathologic models in men with high risk localized prostate cancer: impact of a 22-gene genomic classifier
Performance of clinicopathologic models in men with high risk localized prostate cancer: impact of a 22-gene genomic classifier Open
View article: Clinicopathological characterisation of renal cell carcinoma in young adults: a contemporary update and review of literature
Clinicopathological characterisation of renal cell carcinoma in young adults: a contemporary update and review of literature Open
Aims Renal cell carcinomas are relatively rare in children and young adults. While well characterised in adults, the morphological and molecular characterisation of these tumours in young patients is relatively lacking. The objective of th…
View article: Bosniak Classification of Cystic Renal Masses, Version 2019: An Update Proposal and Needs Assessment
Bosniak Classification of Cystic Renal Masses, Version 2019: An Update Proposal and Needs Assessment Open
Cystic renal cell carcinoma (RCC) is almost certainly overdiagnosed and overtreated. Efforts to diagnose and treat RCC at a curable stage result in many benign neoplasms and indolent cancers being resected without clear benefit. This is es…
View article: Biologic Significance of Magnetic Resonance Imaging Invisibility in Localized Prostate Cancer
Biologic Significance of Magnetic Resonance Imaging Invisibility in Localized Prostate Cancer Open
PURPOSE Multiparametric magnetic resonance imaging (mpMRI) is used widely for prostate cancer (PCa) evaluation. Approximately 35% of aggressive tumors, however, are not visible on mpMRI. We sought to identify the molecular alterations asso…
View article: Genetics of testicular germ cell tumors
Genetics of testicular germ cell tumors Open
Refinements in next-generation sequencing techniques over the last few years have enabled considerable advances in elucidating the genomic, transcriptomic, and epigenetic landscape of TGCTs. Future efforts focused on developing novel treat…
View article: Stereotactic Body Radiation Therapy for Localized Prostate Cancer: A Systematic Review and Meta-Analysis of Over 6,000 Patients Treated On Prospective Studies
Stereotactic Body Radiation Therapy for Localized Prostate Cancer: A Systematic Review and Meta-Analysis of Over 6,000 Patients Treated On Prospective Studies Open
View article: Bladder Cancer: Non-invasive II (PD18)
Bladder Cancer: Non-invasive II (PD18) Open
You have accessJournal of UrologyBladder Cancer: Non-invasive II (PD18)1 Apr 2019Bladder Cancer: Non-invasive II (PD18) View All Author Informationhttps://doi.org/10.1097/01.JU.0000558561.73805.83AboutPDF ToolsAdd to favoritesDownload Cita…
View article: PD18-02 INCREASED URINARY VASCULAR ENDOTHELIAL GROWTH FACTOR D (VEGF-D) LEVELS ARE ASSOCIATED WITH RESPONSE TO COMBINED INTRAVESICAL BACILLUS CALMETTE−GUERIN (BCG) AND ORAL SUNITINIB REGIMEN FOR TREATMENT OF HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC)
PD18-02 INCREASED URINARY VASCULAR ENDOTHELIAL GROWTH FACTOR D (VEGF-D) LEVELS ARE ASSOCIATED WITH RESPONSE TO COMBINED INTRAVESICAL BACILLUS CALMETTE−GUERIN (BCG) AND ORAL SUNITINIB REGIMEN FOR TREATMENT OF HIGH-RISK NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) Open
34.0%), and 19/94 (19.2%) using SB, TB, SBþTB, respectively.Downgrading at RP was observed in 9/94 (9.6%), 12/94 (12.8%), and 19/94 (20.2%) using SB, TB, and SBþTB, respectively.GG concordance was observed in 41/94 (43.6%), 50/94 (53.2%), …
View article: MP13-08 RADIOGENOMIC DISSECTION OF MULTIFOCAL PROSTATE CANCER
MP13-08 RADIOGENOMIC DISSECTION OF MULTIFOCAL PROSTATE CANCER Open
You have accessJournal of UrologyProstate Cancer: Detection & Screening I (MP13)1 Apr 2019MP13-08 RADIOGENOMIC DISSECTION OF MULTIFOCAL PROSTATE CANCER Simpa Salami*, Jeremy Kaplan, Srinivas Nallandhingal, Mandeep Takhar, Jeffrey Tosoian, …
View article: PD66-08 RETHINKING THE ONE-SIZE-FITS-MOST APPROACH TO VENOUS THROMBOEMBOLISM PROPHYLAXIS AFTER RADICAL CYSTECTOMY
PD66-08 RETHINKING THE ONE-SIZE-FITS-MOST APPROACH TO VENOUS THROMBOEMBOLISM PROPHYLAXIS AFTER RADICAL CYSTECTOMY Open
You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation II (PD66)1 Apr 2019PD66-08 RETHINKING THE ONE-SIZE-FITS-MOST APPROACH TO VENOUS THROMBOEMBOLISM PROPHYLAXIS AFTER RADICAL CYSTECTOMY Lauren E Corona*, Udit Singhal,…
View article: Bringing Prostate Cancer Germline Genetics into Clinical Practice
Bringing Prostate Cancer Germline Genetics into Clinical Practice Open
Emerging evidence supports the implementation of germline genetic counseling and testing as a key component of prostate cancer management. Further research is needed to elucidate the clinical significance of lesser known germline mutations…
View article: Prostate Cancer-Specific Mortality Following Salvage Post-Prostatectomy Radiation Therapy: A Competition Between Age and Time to Biochemical Failure
Prostate Cancer-Specific Mortality Following Salvage Post-Prostatectomy Radiation Therapy: A Competition Between Age and Time to Biochemical Failure Open
View article: Society of Abdominal Radiology disease-focused panel on renal cell carcinoma: update on past, current, and future goals
Society of Abdominal Radiology disease-focused panel on renal cell carcinoma: update on past, current, and future goals Open