Samuel Génier
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View article: Nanofilament immunotherapy induces potent antitumor vaccine responses
Nanofilament immunotherapy induces potent antitumor vaccine responses Open
Background Checkpoint inhibitors revolutionized cancer treatment by potentiating antitumor immune responses. However, many patients do not respond to these therapies, often due to the lack of a pre-existing immune response against cancer c…
View article: 1314 Immunostimulatory nanofilaments turn cancer cells into neoantigen agnostic cancer vaccines
1314 Immunostimulatory nanofilaments turn cancer cells into neoantigen agnostic cancer vaccines Open
View article: In vivo mapping of a GPCR interactome using knockin mice
In vivo mapping of a GPCR interactome using knockin mice Open
Significance G-protein–coupled receptors (GPCRs) are the target of approximately 34% of the current medications. However, their in vivo assessment remains arduous, mainly due to their structural properties, their low abundance, and the lac…
View article: L-type prostaglandin D synthase regulates the trafficking of the PGD2 DP1 receptor by interacting with the GTPase Rab4
L-type prostaglandin D synthase regulates the trafficking of the PGD2 DP1 receptor by interacting with the GTPase Rab4 Open
View article: Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor
Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor Open
The delta opioid receptor (DOPr) is known to be mainly expressed in intracellular compartments. It remains unknown why DOPr is barely exported to the cell surface, but it seems that a substantial proportion of the immature receptor is trap…