Samuel J. Bunce
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View article: Structural insights into peptide self‐assembly using photo‐induced crosslinking experiments and discontinuous molecular dynamics
Structural insights into peptide self‐assembly using photo‐induced crosslinking experiments and discontinuous molecular dynamics Open
Determining the structure of the (oligomeric) intermediates that form during the self‐assembly of amyloidogenic peptides is challenging because of their heterogeneous and dynamic nature. Thus, there is need for methodology to analyze the u…
View article: Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β <sub>40</sub> (Aβ <sub>40</sub> ) by the peptide fragment Aβ <sub>16–22</sub>
Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β <sub>40</sub> (Aβ <sub>40</sub> ) by the peptide fragment Aβ <sub>16–22</sub> Open
Combined experiment and simulation reveals a structural mechanism of surface-catalyzed nucleation in Aβ amyloid formation.