Shaohui Huang
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View article: Clinical practice guidelines for the treatment of squamous cell carcinoma of the head and neck: an assessment based on the AGREE II, AGREE-REX tools and the RIGHT checklist
Clinical practice guidelines for the treatment of squamous cell carcinoma of the head and neck: an assessment based on the AGREE II, AGREE-REX tools and the RIGHT checklist Open
Objective The aim of this study was to obtain several published clinical practice guidelines (CPGs) for Head and neck squamous cell carcinoma (HNSCC) and critically assess and compare their quality by using three guideline quality evaluati…
View article: Bmi1 facilitates the progression of cholangiocarcinoma by inhibiting Foxn2 expression dependent on a histone H2A ubiquitination manner
Bmi1 facilitates the progression of cholangiocarcinoma by inhibiting Foxn2 expression dependent on a histone H2A ubiquitination manner Open
Cholangiocarcinoma (CCA), an exceptionally aggressive malignancy originating from the epithelium of the bile duct, poses a formidable challenge in cancer research and clinical management. Currently, attention is focused on exploring the on…
View article: Supra‐Cyanines: Ultrabright Cyanine‐Based Fluorescent Supramolecular Materials in Solution and in the Solid State
Supra‐Cyanines: Ultrabright Cyanine‐Based Fluorescent Supramolecular Materials in Solution and in the Solid State Open
Fluorescent materials with high brightness play a crucial role in the advancement of various technologies such as bioimaging, photonics, and OLEDs. While significant efforts are dedicated to designing new organic dyes with improved perform…
View article: Exploring key genes and mechanisms associated with idiopathic pulmonary fibrosis and lung adenocarcinoma
Exploring key genes and mechanisms associated with idiopathic pulmonary fibrosis and lung adenocarcinoma Open
Background: As the number of studies investigating idiopathic pulmonary fibrosis (IPF) and lung adenocarcinoma (LUAD) continues to grow, increasing evidence supports a strong correlation between these two diseases. However, the underlying …
View article: Composition and function of oral microbiota between gingival squamous cell carcinoma and periodontitis
Composition and function of oral microbiota between gingival squamous cell carcinoma and periodontitis Open
Periodontal pathogens were abundant in GSCC. Cancerous tissues harbor enriched periodontal pathogens while saliva or soft mucosa harbored more periodontal health related bacteria. A high level of Atopobium in saliva and LPS biosynthesis ha…
View article: Cervical lymph node metastases in salivary gland adenoid cystic carcinoma: a systematic review and meta-analysis
Cervical lymph node metastases in salivary gland adenoid cystic carcinoma: a systematic review and meta-analysis Open
Elective neck dissection is unnecessary for all patients with salivary gland ACC of head and neck. Moreover, compared with major salivary glands, MiSGs have a higher cervical lymph node metastases rate in ACC. The overall cervical lymph no…
View article: Efficacy of Adjunctive Bioactive Materials in the Treatment of Periodontal Intrabony Defects: A Systematic Review and Meta-Analysis
Efficacy of Adjunctive Bioactive Materials in the Treatment of Periodontal Intrabony Defects: A Systematic Review and Meta-Analysis Open
Objectives . Lots of bioactive materials have been additionally applied for the treatment of periodontal intrabony defect. However, there is dearth of studies to systematically evaluate the supplementary role of them in periodontal regener…
View article: Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis
Cervical level IIb metastases in squamous cell carcinoma of the oral cavity: a systematic review and meta-analysis Open
Due to the low frequency of level IIb nodal metastases in oral squamous cell carcinoma patients and rare occurrence of isolated level IIb, level IIb dissection could be avoided when the primary lesions were in early stages (T1 and T2), wit…
View article: Association between polymorphisms in pre-miRNA genes and risk of oral squamous cell cancer in a Chinese population
Association between polymorphisms in pre-miRNA genes and risk of oral squamous cell cancer in a Chinese population Open
These findings suggest that miR-499 rs3746444 and miR-146a rs2910164 polymorphisms may contribute to genetic susceptibility to oral squamous cell cancer.
View article: Decreased expression of Beclin-1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma
Decreased expression of Beclin-1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma Open
The autophagy-related gene Beclin-1 is critical in the regulation of tumourigenesis and progression, but its role in oral tongue squamous cell carcinoma (OTSCC) has not yet been reported. This study aimed to investigate Beclin‑1 expression…
View article: Carvacrol suppresses proliferation and invasion in human oral squamous cell carcinoma
Carvacrol suppresses proliferation and invasion in human oral squamous cell carcinoma Open
Carvacrol, a component of thyme oil, as a novel antitumor agent, has been implicated in several types of cancer cells. However, the mechanisms underlying the effect of carvacrol in human oral squamous cell carcinoma (OSCC) remain unclear. …