Sana Sarfaraz
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View article: Emergency twin births in ambulances: a qualitative case study from Sindh, Pakistan
Emergency twin births in ambulances: a qualitative case study from Sindh, Pakistan Open
Emergency childbirth, particularly twin deliveries, poses profound challenges in pre-hospital contexts, where health professionals must often act swiftly under conditions of uncertainty. In rural Pakistan, where access to healthcare facili…
View article: Cumulative Hepatoprotective, Antihyperlipidemic and Antioxidant Effects of Methanolic Seeds Extract of <scp> <i>Citrullus lanatus</i> </scp> , <scp> <i>Cucumis melo</i> </scp> , <scp> <i>Cucumis sativus</i> </scp> , and <scp> <i>Cucurbita maxima</i> </scp> With <scp>GC</scp> – <scp>MS</scp> Profile
Cumulative Hepatoprotective, Antihyperlipidemic and Antioxidant Effects of Methanolic Seeds Extract of <span> <i>Citrullus lanatus</i> </span> , <span> <i>Cucumis melo</i> </span> , <span> <i>Cucumis sativus</i> </span> , and <span> <i>Cucurbita maxima</i> </span> With <span>GC</span> – <span>MS</span> Profile Open
The complex pathophysiological mechanism of nonalcoholic fatty liver (NAFLD) disease has made the prevention and treatment of the disease problematic. The aim of the current study is to evaluate the cumulative hepatoprotective, antihyperli…
View article: Dose-Dependent Effects of Sacubitril/Valsartan on Functional Class and Echocardiographic Parameters in Heart Failure with Reduced Ejection Fraction: A Six-Week Follow-Up Study
Dose-Dependent Effects of Sacubitril/Valsartan on Functional Class and Echocardiographic Parameters in Heart Failure with Reduced Ejection Fraction: A Six-Week Follow-Up Study Open
Objectives: This study aimed to compare the dose-dependent effects of sacubitril/valsartan on functional class and echocardiographic parameters over a six-week period. Methodology: This prospective, longitudinal study was conducted between…
View article: Mapping Gestational Diabetes Mellitus – A Narrative Review of Key Determinants and Epidemiology
Mapping Gestational Diabetes Mellitus – A Narrative Review of Key Determinants and Epidemiology Open
Gestational diabetes mellitus (GDM) is a glucose intolerance disorder that arises during pregnancy, posing significant risks to both maternal and neonatal health. The global burden of GDM is increasing, reflecting changes in demographic, g…
View article: The Relationship between Sleep Disturbances and Glycemic Control in Children with Type 1 Diabetes
The Relationship between Sleep Disturbances and Glycemic Control in Children with Type 1 Diabetes Open
Children with Type 1 Diabetes Mellitus (T1DM) require careful glycemic management to prevent both acute and long-term complications. Objectives: To evaluate the association between sleep disturbances and glycemic control in children and ad…
View article: Association between Hemoglobin Levels and Severity of Coronary Artery Disease among Patients Presenting with ST- Segment Elevation Myocardial Infarction
Association between Hemoglobin Levels and Severity of Coronary Artery Disease among Patients Presenting with ST- Segment Elevation Myocardial Infarction Open
Objective: This study aimed to elucidate the association between hemoglobin levels (anemia) and the severity of coronary artery disease (CAD) among patients experiencing ST-segment elevation myocardial infarction (STEMI). Methods: This pro…
View article: Fabrication and evaluation of nanoemulsion based insulin loaded microneedles for transdermal drug delivery
Fabrication and evaluation of nanoemulsion based insulin loaded microneedles for transdermal drug delivery Open
Aim: Insulin therapy require self-administration of subcutaneous injection leading to painful and inconvenient drug therapy. The aim is to fabricate nanoemulsion (NE) based insulin loaded microneedles with improved bioavailability a…
View article: Frequency of multi-vessel disease and its association with N Terminal-Pro Brain Natriuretic Peptide Levels among patients with First ST-Elevation Myocardial Infarction.
Frequency of multi-vessel disease and its association with N Terminal-Pro Brain Natriuretic Peptide Levels among patients with First ST-Elevation Myocardial Infarction. Open
Background and Aims: To determine the frequency of multi-vessel disease among patients with First ST-Elevation Myocardial Infarction and to identify the cutoff value of N Terminal-Pro Brain Natriuretic Peptide (NT-proBNP) for diagnosis of …
View article: Anxiolytic and Antidepressant Effect of Phaseolus vulgaris on Animal Models
Anxiolytic and Antidepressant Effect of Phaseolus vulgaris on Animal Models Open
An experimental study was conducted using rodents at different doses to evaluate the effect of Phaseolus vulgaris (red beans) on cage crossing, head dip, open field, elevated plus maze, and light and dark apparatus for anxiety and forced s…
View article: Clinical Inertia in Terms of Recurrent Hospitalization in the Treatment of Heart Failure Between General Physicians and Cardiologists
Clinical Inertia in Terms of Recurrent Hospitalization in the Treatment of Heart Failure Between General Physicians and Cardiologists Open
Cardiologists are more likely to use clinical guideline-supported therapies than general physicians, a fact that has been shown to reduce readmissions. Objective: To compare the intensification of heart failure treatment and its course wit…
View article: ASSOCIATION OF HEART RATE AT HOSPITAL DISCHARGE AND REHOSPITALIZATION OF PATIENTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION
ASSOCIATION OF HEART RATE AT HOSPITAL DISCHARGE AND REHOSPITALIZATION OF PATIENTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION Open
Background: One of the major causes of cardiovascular morbidity and mortality is heart failure. The study aims to assess the effect of heart rate on the incidence of rehospitalization in patients with heart failure and reduced ejection fra…
View article: Review on Biological Management of Bactrocera zonata through Pathogenic Activity of Beauveria bassiana
Review on Biological Management of Bactrocera zonata through Pathogenic Activity of Beauveria bassiana Open
Bactrocera zonata is the destructive pest of peach, mango and banana by causing Significant economic losse It reduces fruit quality, which directly causes decline in export of these economical fruits. Many management strategies were carrie…
View article: Efficacy of Azadirachta indica and Datura stramonium Extract with Ethanol against Different Life Stages of Tribolium castinium
Efficacy of Azadirachta indica and Datura stramonium Extract with Ethanol against Different Life Stages of Tribolium castinium Open
Tribolium castinium is a devastating stored grain pests of many cereals. Both the larval and adult stages of insect are considered as voracious feeder of cereals. The adult of T. castinium secrete certain type of excretion that give foul s…
View article: Comparison between the Levels of N Terminal Pro-Brain Natriuretic Peptide and Troponin I to Predict Left Ventricular Ejection Fraction in Patients Presenting with First ST-Elevation Myocardial Infarction
Comparison between the Levels of N Terminal Pro-Brain Natriuretic Peptide and Troponin I to Predict Left Ventricular Ejection Fraction in Patients Presenting with First ST-Elevation Myocardial Infarction Open
Objectives: To compare the levels of N Terminal- ProBrain natriuretic peptide (NT-proBNP) and Troponin I (Trop I) to predict left ventricular ejection fraction (LVEF) in patients presenting with first ST-elevation myocardial infarction (ST…
View article: VISUAL OUTCOMES WITH INTRAOCULAR TRIFOCAL LENS IMPLANT
VISUAL OUTCOMES WITH INTRAOCULAR TRIFOCAL LENS IMPLANT Open
Background: Cataract surgery has become one of the most common surgeries in the world with one in every four surgeries performed being a cataract extraction and the numbers are expected to increase by 16 percent in the USA alone by 2024 as…
View article: Vigna Unguiculata as an Anxiolytic Agent: Evidence from Animal Model Studies
Vigna Unguiculata as an Anxiolytic Agent: Evidence from Animal Model Studies Open
Anxiety has spread worldwide and is only getting worse, posing a serious threat to mental health and general well-being. If anxiety is not managed, it can result in severe depression and other health issues. The current study intends to in…
View article: Use of Single Shoulder Handling Bag: Scoliosis and Musculoskeletal Pain in School Going Children. “A Cross Sectional Study”
Use of Single Shoulder Handling Bag: Scoliosis and Musculoskeletal Pain in School Going Children. “A Cross Sectional Study” Open
Objectives: The objectives of the study were to assess the Frequency of musculoskeletal pain, and to check whether single strapped bags are culprit of causing scoliosis in school going children or not as compared to other types of school b…
View article: IMPACT OF LOW-DOSE SACUBITRIL-VALSARTAN ON HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION
IMPACT OF LOW-DOSE SACUBITRIL-VALSARTAN ON HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH HEART FAILURE AND REDUCED EJECTION FRACTION Open
Objectives: The present study aimed to observe the beneficial effects of sacubitril-valsartan at a lower dose of 24/26mg BID in a third-world country (Pakistan).
Methodology: This was a randomized, prospective, observational cohort study …
View article: Nanoclay-Based Composite Films for Transdermal Drug Delivery: Development, Characterization, and in silico Modeling and Simulation
Nanoclay-Based Composite Films for Transdermal Drug Delivery: Development, Characterization, and in silico Modeling and Simulation Open
The study demonstrated that HNTs could be effectively used as rate controlling agent in matrix type transdermal formulations.
View article: Screening of different doses of lyophilized beetroot for their hematopoietic potential.
Screening of different doses of lyophilized beetroot for their hematopoietic potential. Open
Background: Beetroots are considered a vital source of nutrition and are usually incorporated into the daily diet to prevent different disease conditions. The therapeutic effect observed is due to the presence of active ingredients in the …
View article: Evaluation of Hepatoprotective effects of different doses of Lyophilized Beetroot powder in albino rabbits.
Evaluation of Hepatoprotective effects of different doses of Lyophilized Beetroot powder in albino rabbits. Open
Beta vulgaris L. is a vegetable most commonly consumed in salads and has been shown to possess multiple benefits. This research was carried out to observe the effects of Beta vulgaris powder at different doses orally in albino rabbits on l…
View article: Rising trend of Nutraceuticals: Evaluation of lyophilized beetroot powder at different doses for its hypolipidemic effects.
Rising trend of Nutraceuticals: Evaluation of lyophilized beetroot powder at different doses for its hypolipidemic effects. Open
A diet comprising of nutrients that would control hypertension as well as hyperlipidemia would be very beneficial over all. This study aimed to assess the effect of lyophilized beet root powder at different doses on lipid profile and hyper…
View article: Higher incidence of prescribing rates and utilization of broad spectrum cephalosporin in young patients: A retrospective observational study in a tertiary care hospital.
Higher incidence of prescribing rates and utilization of broad spectrum cephalosporin in young patients: A retrospective observational study in a tertiary care hospital. Open
Frequent use of antibiotics has been developed resistance and the use of broad spectrum cephalosporin must be limited in children. The study evaluated the association of prescribing patterns of third generation cephalosporin with diagnosis…
View article: Determination of anxiolytic and antidepressant like activity of hydro alcoholic fruit extract of Pyrus communis (L.) and its impact on the memory after chronic dosing in animal models.
Determination of anxiolytic and antidepressant like activity of hydro alcoholic fruit extract of Pyrus communis (L.) and its impact on the memory after chronic dosing in animal models. Open
The purpose of this study was to evaluate the anxiolytic and antidepressant activity of ethanolic fruit extract of Pyrus communis (pear), in comparison with escitalopram in rodents (rats and mice). Thirty Wistar rats of about 200-250gm and…
View article: Effects on Biodiversity in Climate Change Scenario
Effects on Biodiversity in Climate Change Scenario Open
C limate change, a serious global concern, is caused by human activity and poses a variety of hazards to all living things.Increasing anthropogenic activities are responsible for the global warming that has happened during the last five de…
View article: To assess the co-relation between corrected qt interval prolongation and abnormal scan during vasodilator nuclear stress test.
To assess the co-relation between corrected qt interval prolongation and abnormal scan during vasodilator nuclear stress test. Open
In the detection of coronary heart diseases amongst the non-invasive techniques the role of myocardial perfusion imaging is indexed. The rationale of this study was to compare the different parameters and the association between the exerci…
View article: Antiemetic Effect of Fruit Extracts of Trapa bispinosa Roxb. in Chick Emesis Model
Antiemetic Effect of Fruit Extracts of Trapa bispinosa Roxb. in Chick Emesis Model Open
Background: Vomiting and nausea are common symptoms associated with many diseased conditions. They also occur as side effects due to intake of certain medications. Natural remedies are nowadays being considered as a better alternate compar…
View article: Assessment of the co-relation between 1st set of Troponin I, age, duration of chest pain and LVEF in patients presenting with first stemi and treatment protocol followed.
Assessment of the co-relation between 1st set of Troponin I, age, duration of chest pain and LVEF in patients presenting with first stemi and treatment protocol followed. Open
Coronary heart disease is the cause of 17.1 million deaths per year throughout the world. The rationale of this study was to determine the importance of 1st set of Troponin I in relation to age, duration of chest pain and left ventricular …
View article: Effect of different doses of lyophilized beetroot on fertility and reproductive hormones.
Effect of different doses of lyophilized beetroot on fertility and reproductive hormones. Open
Infertility has recently been a common issue for which multiple medicinal as well as surgical treatments are available. Beta vulgaris commonly referred to as garden beet is one of the most utilized vegetable especially in salad dressings. …
View article: Fennel fortified diet: New perspective with regard to fertility and sex hormones.
Fennel fortified diet: New perspective with regard to fertility and sex hormones. Open
The objective of this study was to evaluate the effect of Foeniculum vulgare (FV) on fertility of mice and on serum sex hormone values of rats and rabbits. We used powdered form of Foeniculum vulgare seed and added it to food of mice, rats…