Explanipedia

Clinical Conditions Associated with Elevated Serum Levels of Polyclonal Free Light Chains Open

Giampaolo Talamo, Marcelle Meseeha, Muneer Khan, Julie L. Richards, Shobha Mandal , et al. · 2025

Background: Polyclonal gammopathy with elevation of the intact immunoglobulin (Ig) molecules is a laboratory finding commonly observed in a variety of inflammatory disorders, such as infections, autoimmune diseases, and cancer. Little is k…

Comprehensive Computational Analysis of TP53 Mutation for Improving Precision Oncology Open

Shobha Mandal · 2024

Development of significantly hard hypereutectoid plain carbon steel through incomplete austenitization based cyclic quenching treatment Open

Joydeep Maity, M.G. Dastidar, Shobha Mandal, Sudesh Sharma, Sunil Kumar Chaudhary , et al. · 2024

In this investigation hot rolled steel bars of 1.24 weight % carbon steel are subjected to incomplete austenitization based cyclic quenching treatment. Each cycle consists of inserting the specimen in an electric resistance furnace at a te…

Artificial Intelligence and Deep Learning in Revolutionizing Brain Tumor Diagnosis and Treatment: A Narrative Review Open

Shobha Mandal, Subhadeep Chakraborty, Muhammad Ayaz Tariq, Kamran Ali, Zenia Elavia , et al. · 2024

Admissions for posttransplant lymphoproliferative disorder: a 9-year longitudinal analysis of the National (Nationwide) Inpatient Sample Open

Zain El‐amir, Abdur Jamil, Dhanshree Solanki, Uvesh Mansuri, Midhun Mathew , et al. · 2024

Our study provides insight into the changes in hospitalizations for PTLD over nearly a decade, showing an increase in hospitalizations and reports of comorbidities.

Co-infectious Uveitis With Syphilis and Lyme Disease: A Case Report Open

Shobha Mandal, Hamnah Tayyab, Subhash C. Mandal, Abdelhaleem Sideeg · 2024

Revolutionizing Breast Cancer Detection With Artificial Intelligence (AI) in Radiology and Radiation Oncology: A Systematic Review Open

Zubir Rentiya, Shobha Mandal, Pugazhendi Inban, Hemika Vempalli, Rishika Dabbara , et al. · 2024

The number one cause of cancer in women worldwide is breast cancer. Over the last three decades, the use of traditional screen-film mammography has increased, but in recent years, digital mammography and 3D tomosynthesis have become standa…

Hematologic Complications of Tick Bites and Tick-Borne Illness: A Brief Narrative Review Open

Asim Kichloo, Zain El‐amir, Amar Ghaleb, Shobha Mandal, Paritharsh Ghantasala · 2024

Introduction: Tick-borne illnesses are rising in the United States, and tick bites can result in hematologic complications including anemia, thrombocytopenia, pancytopenia, and even life-threatening sequelae like disseminated intravascular…

Parathyroid Carcinoma: A Diagnostic Challenge – A Case Report Open

F N U Manas, Shobha Mandal, Barbara Mols-Kowalczewski · 2022

Introduction Parathyroid carcinoma is a rare endocrine carcinoma, presenting as hypercalcemia with elevated parathyroid hormone (PTH) levels, and with renal and bone involvement. It is often misdiagnosed as parathyroid adenoma, resulting i…

Mechanical Aortic Valve Thrombosis Successfully Treated With Intravenous Thrombolytic Therapy: A Case Report Open

Shobha Mandal, Dipesh Rohita, Sanjay Paudel, Alex Stroia, Benjamin R. McClintic · 2022

Mechanical prosthetic valves, like all foreign bodies, are thrombogenic, requiring anticoagulation to avoid thrombosis and reduce the risk of catastrophic stroke. We reported a case of a 42-year-old female that developed mechanical valve t…

A case report on non‐metastatic Ewing sarcoma of the lumbar spine in a young patient Open

Shobha Mandal, Srijana Baniya, Dipesh Rohita, Gopal Kumar Yadav, Philip Lowry · 2022

Background Ewing sarcoma (ES), the second most common malignant bone tumor after osteosarcoma in the second decade, occurs in 0.9% of cases as the primary non‐sacral form. Case A 20‐years‐old male presented with acute paraparesis of bilate…

The Role of Cholecystectomy in Hyperkinetic Gallbladder: A Retrospective Cohort Study in a Rural Hospital Open

Rachel Hart, Sri H Senapathi, Emma K. Satchell, Shobha Mandal, Margaret McAndrew , et al. · 2022

A Case Report on the Rare Presentation of the Primary Spinal Epidural Non-Hodgkin's Lymphoma Open

Shobha Mandal, Mary Grace Bethala, Dipesh Rohita, Sarah A Branch, Phillip J. Lowry · 2022

A Case Report on Solitary Extramedullary Plasmacytoma of the Pleura Open

Shobha Mandal, Saswat Jha, Mary Grace Bethala, Naaila Ali, Rahul Gosain · 2022

A Case Report on Mechanical Aortic Valve Thrombosis Successfully Treated with Intravenous Thrombolytic Therapy. Open

Shobha Mandal, Dipesh Rohita, Alex Stroia, S. Paudel, Benjamin R. McClintic · 2022

Mechanical prosthetic valves, like all foreign bodies, are thrombogenic, requiring anticoagulation to avoid thrombosis and reduce the risk of catastrophic stroke. We reported a case of a 42-year-old female that developed mechanical valve t…

A Rare Case of Metachronous Quadruple Primary Malignancies in a Single Patient: A Case Report and Comprehensive Literature Review Open

Manisha Raikar, Shobha Mandal, F N U Manas, Victor O. Kolade · 2022

Demographics, comorbidities, and laboratory parameters in hospitalized patients with SARS-CoV2 infection at a community hospital in rural Pennsylvania Open

Vrushali Pachpande, Sri Senapathi, Karen Williams, Seungwoo Chai, Shobha Mandal , et al. · 2022

Introduction Inherent differences as well as health disparities among rural and urban populations warrant further studies focused on the characteristics and outcomes in COVID-19 patients in a rural setting. The aim of this study was to des…

A Case of Congenital Methemoglobinemia: Rare but Real Open

Sanjay Paudel, Nirajan Adhikari, Shobha Mandal, Panit Srivatana · 2022

Methemoglobin (MetHb) is a form of hemoglobin in which iron in Hb is in an oxidized form (ferric) instead of ferrous, making it difficult to bind with oxygen. Usually, MetHb is present in small quantities (<1%) in humans, but once MetHb in…

A Case Report of Advanced Cervical Cancer in a Patient Non-compliant With Age-Appropriate Screening Open

Shobha Mandal, Sohaib Shabih, Jagdesh Kumar, Surendra Shah · 2022

Cervical carcinoma is one of the preventable malignancies in the United States. Age-appropriate screening has decreased the incidence of cervical cancer. A multitude of age-appropriate screening methods is available including Papanicolaou …

A CASE OF ANTI-HU-ANTIBODIES-MEDICATED ENCEPHALITIS INDUCED BY ATEZOLIZUMAB IN EXTENSIVE-STAGE SMALL CELL LUNG CANCER Open

Shobha Mandal, Rahul Gosain · 2021

A CASE REPORT ON EXTENSIVE ARTERIAL THROMBOSIS AS A COMPLICATION OF COVID-19 INFECTION Open

Shobha Mandal, Sumit Gami, Sushmita Khadka, Subash Ghimire · 2021

A RARE PRESENTATION OF PLEURAL PLASMACYTOMA Open

Shobha Mandal, Layla Sulaiman, Shista Priyadarshini, ONEEB SANUALLAH, David E. Lucero , et al. · 2021

Hyperprogression: A Unique Phenomenon of Progression of Existing Tumor Secondary to Immunotherapy Open

Shobha Mandal, Barun Ray, Srijana Baniya Sharma, Joyson Poulose, Vineela Kasireddy · 2021

Immunotherapy is a relatively new approach for cancer treatment that has demonstrated prolonged survival by enhancing the body's immunologic response among advanced cancer patients. Although the benefits of immunotherapy have been well doc…

Air under the diaphragm—perforation or Chilaiditi sign? Open

Shobha Mandal, Sneha Singh, Barun Ray, Rahul Thakur, Anish Shah , et al. · 2021

Chilaiditi sign is a rare radiological finding in which the colon is interposed between the liver and the abdominal wall. Once patients become symptomatic, the condition is called Chilaiditi syndrome. We discuss a unique patient who presen…

A Case of Mucosa-Associated Lymphoid Tissue Lymphoma of the Bladder: An Extremely Rare Presentation Open

Shobha Mandal, Chandrakala Dadeboyina, Srijana Baniya Sharma, Suryakala Dadeboyina, Joyson Poulose · 2021

Extranodal mucosa-associated lymphoid tissue (MALT) is a type of non-Hodgkin's lymphoma (NHL). It commonly involves the GI tract, but the involvement of the urinary bladder is very rare. It comprises less than 1% of bladder tumors and 0.2%…

Medulloblastoma in an Adult Female Patient: A Rare Presentation Open

Shobha Mandal, Bishnu Mohan Singh, Sumit Gami, Sunil Kumar Shah, Joyson Poulose · 2021

Medulloblastoma (MB) is an aggressive malignant tumor of the posterior fossa of the CNS that mainly affects children younger than 15 years of age. It is uncommon in the adult population compared to children. Any adult patient presenting wi…

A case report of a massive cardiac intimal sarcoma manifesting as syncope during a stress test Open

Mahin Rehman, Ashraf El‐Dabh, Shobha Mandal, Sudhakar Sattur · 2021

Background Syncope has many aetiologies but from a cardiac standpoint, if arrhythmogenic and ischaemic causes are not present, obstructive lesions should be considered. Cardiac spindle cell sarcomas are incredibly rare and difficult to cur…

A Case Report on Primary Central Nervous System Lymphoma in Immunocompetent Individual Open

Shobha Mandal, Sunil Kumar Shah, Sumit Gami, Barun Ray, Joyson Poulose · 2021

A Case Report on Adenosquamous Carcinoma of Gallbladder: A Very Rare Malignancy Open

Shobha Mandal, Sravan K. Ponnekanti, Chandrakala Dadeboyina, Anusha Tipparthi, Vineela Kasireddy · 2021

A Case Report on Extensive Arterial Thrombosis: A Rare Complication of COVID-19 Infection Open

Shobha Mandal, Sumit Gami, Sushmita Khadka, Barun Ray, Subash Ghimire · 2021

Coronavirus disease (COVID-19) is a global health crisis leading to increased morbidity and mortality worldwide. It is associated with increased activation of the clotting system leading to thrombotic complications increasing the risk of l…

Shobha Mandal YOU? Author Swipe