Sikha Saha YOU? Author Swipe

Last 10y

Expert consensus on solutions to improve implementation of NICE type 2 diabetes guideline (NG28) by health systems in England: a Delphi panel by the INNOVATE-28 Working Group Open

Warda Tahir, Hannah Beba, Gail Fortes-Mayer, Partha Kar, Nazish Khan , et al. · 2025

Objectives To provide expert consensus recommendations to support health systems in England to improve prioritisation and implementation of cardiovascular and renal risk-based type 2 diabetes (T2D) care, achieving quality improvement in li…

Upconversion nanoparticle-based optical biosensor for early diagnosis of stroke Open

Pragati Kakkar, Tarun Kakkar, Padmaja Parameswaran Nampi, Gin Jose, Sikha Saha · 2025

Over 17 million people experience a stroke episode annually, with 5.9 million deaths. Stroke is diagnosed by physical tests and neuroimaging which need to be performed quickly to determine if the stroke is caused by ischaemia or haemorrhag…

Circulating Blood-Brain Barrier Proteins for Differentiating Ischaemic Stroke Patients from Stroke Mimics Open

Pragati Kakkar, Meaad Almusined, Tarun Kakkar, Theresa Munyombwe, Linetty Makawa , et al. · 2024

Background: Stroke is one of the leading causes of death and disability worldwide. The diagnosis of stroke remains largely clinical, yet widely used stroke scoring systems and brain imaging do not satisfactorily allow the distinction of is…

Circulating Blood-Brain Barrier Proteins for Differentiating Ischaemic Stroke Patients from Stroke Mimics Open

Pragati Kakkar, Meaad Almusined, Tarun Kakkar, Theresa Munyombwe, Linetty Makawa , et al. · 2024

Upconversion Nanoparticle-Based Optical Biosensor for Early Diagnosis of Stroke Open

Pragati Kakkar, Tarun Kakkar, Padmaja Parameswaran Nampi, Gin Jose, Sikha Saha · 2024

Investigation of Blood-Brain Barrier proteins as Potential Biomarkers in a Murine Model of Ischaemic Stroke Open

Meaad Almusined, Pragati Kakkar, Nadira Yuldasheva, Hema Viswambharan, Tarun Kakkar , et al. · 2023

The blood-brain barrier (BBB) acts as a specialized structure separating the brain from peripheral blood circulation and plays an important role in brain function. Following an ischaemic stroke or cerebral ischaemia, the BBB is damaged lea…

CCDC 2132600: Experimental Crystal Structure Determination Open

Niladri Biswas, Sikha Saha, Barun Kumar Biswas, Manas Chowdhury, Ashikur Rahaman , et al. · 2022

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 2124342: Experimental Crystal Structure Determination Open

Barun Kumar Biswas, Niladri Biswas, Sikha Saha, Ashikur Rahaman, Deba Prasad Mandal , et al. · 2022

Surface modified hexagonal upconversion nanoparticles for the development of competitive assay for biodetection Open

Padmaja Parameswaran Nampi, Alexander Vakurov, Sikha Saha, Gin Jose, Paul A. Millner · 2022

Up-conversion nanoparticles (UCNPs) of sodium yttrium fluoride with ytterbium and erbium ions as sensitizer and activator (β-NaYF₄/Yb³⁺/Er³⁺) have been synthesised by a solvothermal method. The synthesised …

Current approaches and advances in the imaging of stroke Open

Pragati Kakkar, Tarun Kakkar, Tufail Patankar, Sikha Saha · 2021

A stroke occurs when the blood flow to the brain is suddenly interrupted, depriving brain cells of oxygen and glucose and leading to further cell death. Neuroimaging techniques, such as computed tomography and magnetic resonance imaging, h…

CCDC 1938884: Experimental Crystal Structure Determination Open

Niladri Biswas, Sikha Saha, Barun Kumar Biswas, Manas Chowdhury, Ashikur Rahaman , et al. · 2021

Issue information Open

Hari Bhat, David A. Lawrence, Richard Parsons, Jeremy Hargrove, Isaac A. Adedara , et al. · 2021

Barium yttrium fluoride based upconversion nanoparticles as dual mode image contrast agents Open

Padmaja Parameswaran Nampi, Alexander Vakurov, Hema Viswambharan, Jürgen E. Schneider, Rik Brydson , et al. · 2021

Dual labeled contrast agents could provide better complementary information for bioimaging than available solely from a single modality. In this paper we investigate the suitability of Yb³⁺ and Er³⁺-doped BaYF₅

Issue information Open

Hari Bhat, David A. Lawrence, Richard Parsons, Jeremy Hargrove, Isaac A. Adedara , et al. · 2021

Affimer-Based Europium Chelates Allow Sensitive Optical Biosensing in a Range of Human Disease Biomarkers Open

Eiman Al-Enezi, Alexander Vakurov, Amy Eades, Mingyu Ding, Gin Jose , et al. · 2021

The protein biomarker measurement has been well-established using ELISA (enzyme-linked immunosorbent assay), which offers good sensitivity and specificity, but remains slow and expensive. Certain clinical conditions, where rapid measuremen…

Issue information Open

Hari Bhat, David A. Lawrence, Richard Parsons, Jeremy Hargrove, Isaac A. Adedara , et al. · 2020

Issue information Open

Hari Bhat, David A. Lawrence, Richard Parsons, Jeremy Hargrove, Isaac A. Adedara , et al. · 2020

CCDC 1981605: Experimental Crystal Structure Determination Open

Barun Kumar Biswas, Sikha Saha, Niladri Biswas, Manas Chowdhury, Antonio Frontera , et al. · 2020

CCDC 1981309: Experimental Crystal Structure Determination Open

Barun Kumar Biswas, Sikha Saha, Niladri Biswas, Manas Chowdhury, Antonio Frontera , et al. · 2020

Editorial: Cerebrovascular and Neurodegenerative Diseases - New Insights Into Molecular Cell Biology and Therapeutic Targets Open

Sikha Saha, Sriharsha Kantamneni · 2019

EDITORIAL article Front. Neurol., 13 December 2019Sec. Neurodegeneration Volume 10 - 2019 | https://doi.org/10.3389/fneur.2019.01322

Selective cellular imaging with lanthanide‐based upconversion nanoparticles Open

Padmaja Parameswaran Nampi, Alexander Vakurov, Lewis E. MacKenzie, Nigel S. Scrutton, Paul A. Millner , et al. · 2018

Upconversion nanoparticles (UCNPs) with sodium yttrium fluoride, NaYF 4 (host lattice) doped with Yb 3+ (sensitizer) and Er 3+ (activator) were synthesized via hydrothermal route incorporating polyethyleneimine (PEI) for their long‐term st…

A novel dynamic multicellular co-culture system for studying individual blood-brain barrier cell types in brain diseases and cytotoxicity testing Open

Patrícia Miranda-Azpiazu, Stavros Panagiotou, Gin Jose, Sikha Saha · 2018

Front Cover: Photoluminescence intensity ratio of Eu‐conjugated lactates—A simple optical imaging technique for biomarker analysis for critical diseases (J. Biophotonics 5/2018) Open

Tarun Kakkar, Nikita Thomas, Eric Kumi‐Barimah, Gin Jose, Sikha Saha · 2018

Eu 3+ integrated photoluminescence intensity ratio (PLIR) approach for optical detection of lactates in blood serum, plasma and confocal imaging of brain tissues has very high potential for exploitation of this technique in both in vitro m…

The theoretical molecular weight of NaYF 4 :RE upconversion nanoparticles Open

Lewis E. MacKenzie, Jack A. Goode, Alexander Vakurov, Padmaja Parameswaran Nampi, Sikha Saha , et al. · 2018

Upconversion nanoparticles (UCNPs) are utilized extensively for biomedical imaging, sensing, and therapeutic applications, yet the molecular weight of UCNPs has not previously been reported. Herein, we present a theory based upon the cryst…

CCDC 1560984: Experimental Crystal Structure Determination Open

Sikha Saha, Niladri Biswas, Ashok Sasmal, Carlos J. Gómez‐García, Eugenio Garribba , et al. · 2018

CCDC 1560985: Experimental Crystal Structure Determination Open

Sikha Saha, Niladri Biswas, Ashok Sasmal, Carlos J. Gómez‐García, Eugenio Garribba , et al. · 2018

Subchronic hypoxia pretreatment on brain pathophysiology in unilateral common carotid artery occluded albino rats Open

Kusal K. Das, SaeedM Yendigeri, Bheemshetty S. Patil, Ishwar B. Bagoji, RChandramouli Reddy , et al. · 2018

This study clearly demonstrates that subchronic hypoxia pretreatment can reduce ischemic brain injury by unilateral common carotid artery occlusion in rats.

Photoluminescence intensity ratio of Eu‐conjugated lactates—A simple optical imaging technique for biomarker analysis for critical diseases Open

Tarun Kakkar, Nikita Thomas, Eric Kumi‐Barimah, Gin Jose, Sikha Saha · 2017

Instant measurement of elevated biomarkers such as lactic acid offers the most promising approaches for early treatment and prevention of many critical diseases including cardiac arrest, stroke, septic shock, trauma, liver dysfunction, as …

The theoretical molecular weight of NaYF<sub>4</sub>:RE upconversion nanoparticles Open

Lewis E. MacKenzie, Jack A. Goode, Alexander Vakurov, Padmaja Parameswaran Nampi, Sikha Saha , et al. · 2017

Upconversion nanoparticles (UCNPs) are utilized extensively for biomedical imaging, sensing, and therapeutic applications, yet the molecular weight of UCNPs has not previously been reported. We present a theory based upon the crystal struc…

P23 A three dimensional (3D) human in vitro blood-brain barrier (BBB) Open

Patrícia Miranda-Azpiazu, Stavros Panagiotou, Gin Jose, Sikha Saha · 2016

Rationale The blood-brain barrier (BBB) is the crucial frontier between the blood and the brain. It has been suggested a relationship between diabetes or stroke and a loss of BBB integrity, although the mechanisms of these BBB changes sti…