Sandhya Mangalore
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View article: Development and validation of fluorine-18[18F]-NAV4694 for imaging amyloid plaques in AD
Development and validation of fluorine-18[18F]-NAV4694 for imaging amyloid plaques in AD Open
View article: The Enigma of Reflex Eating Epilepsy: A Cohort Study of Fifty Patients with Insights from Multimodal Evaluation
The Enigma of Reflex Eating Epilepsy: A Cohort Study of Fifty Patients with Insights from Multimodal Evaluation Open
View article: Ictal EEG Pattern and Outcome Analysis in Temporal Lobe Epilepsy with Hippocampal Sclerosis: Insights from a Single-Center Cohort
Ictal EEG Pattern and Outcome Analysis in Temporal Lobe Epilepsy with Hippocampal Sclerosis: Insights from a Single-Center Cohort Open
View article: Multimodal Imaging and Logistic Weighted Cognitive Scores for Classification of MCI, AD, and FTD Subtypes
Multimodal Imaging and Logistic Weighted Cognitive Scores for Classification of MCI, AD, and FTD Subtypes Open
Background Differentiating between mild cognitive impairment (MCI), Alzheimer’s disease (AD), and frontotemporal dementia (FTD) subtypes remains a clinical challenge due to overlapping cognitive symptoms, structural atrophy, and metabolic …
View article: A Comparative Analysis of Different MRI Sequences Dedicated for Invivo Detection of Mineralization in a Single Large Cohort of Progressive Supranuclear Palsy and Healthy Controls
A Comparative Analysis of Different MRI Sequences Dedicated for Invivo Detection of Mineralization in a Single Large Cohort of Progressive Supranuclear Palsy and Healthy Controls Open
Iron plays an important role in normal brain metabolism. Increase in brain iron is a part of the normal brain development, but an excessive deposition of brain iron may be a risk factor for degenerative diseases. At the clinical setting, t…
View article: Production of Fluorine-18[18f]-Nav4694 on an Fx2n Synthesis Module for Imaging Amyloid Plaques
Production of Fluorine-18[18f]-Nav4694 on an Fx2n Synthesis Module for Imaging Amyloid Plaques Open
View article: Multiplex connectomics reveal altered networks in frontotemporal dementia: A multisite study
Multiplex connectomics reveal altered networks in frontotemporal dementia: A multisite study Open
A network neuroscience perspective can significantly advance the understanding of neurodegenerative disorders, particularly frontotemporal dementia (FTD). This study employed an innovative multiplex connectomics approach, integrating corti…
View article: Challenges in diagnosis and management in elderly presenting with very late-onset psychiatric symptoms and N-methyl-D-aspartate receptor autoimmune encephalitis
Challenges in diagnosis and management in elderly presenting with very late-onset psychiatric symptoms and N-methyl-D-aspartate receptor autoimmune encephalitis Open
N-methyl-D-aspartate receptor (NMDAR) encephalitis presents with psychiatric and neurological symptoms at various stages of the disease course. We present the case of a 70-year-old elderly woman with hypertension, diabetes mellitus, and a …
View article: Role of 6-Fluoro-18F-l-3,4-DOPA MR-PET in Clinical Workup in Movement Disorders Cases: An Exploratory Study in a Tertiary Care Neuropsychiatric Setup
Role of 6-Fluoro-18F-l-3,4-DOPA MR-PET in Clinical Workup in Movement Disorders Cases: An Exploratory Study in a Tertiary Care Neuropsychiatric Setup Open
Introduction: 6-Fluoro-18F-l-3,4-dihydroxyphenylalanine (18F-DOPA) is primarily used to differentiate nondopamine deficient symptomatic subjects from Parkinsonian disorders and various etiologies from one another, which otherwise can be ch…
View article: Magnetoencephalography Profile of Patients with Drug-Resistant Focal Epilepsy and Normal MRI
Magnetoencephalography Profile of Patients with Drug-Resistant Focal Epilepsy and Normal MRI Open
Background and Objectives: Magnetoencephalography (MEG) could be a valuable tool in the presurgical evaluation of drug-resistant epilepsy (DRE), especially when the initial evaluation is inconclusive. In this retrospective study, we descri…
View article: Prospective Study to Evaluate the Role of Dual Point Contrast-enhanced Magnetic Resonance Imaging in Differentiation of Brain Tumoral from Nontumoral Tissue: A Magnetic Resonance/PET Study
Prospective Study to Evaluate the Role of Dual Point Contrast-enhanced Magnetic Resonance Imaging in Differentiation of Brain Tumoral from Nontumoral Tissue: A Magnetic Resonance/PET Study Open
Background and Purpose: Follow-up imaging of gliomas is crucial to look for residual or recurrence and to differentiate them from nontumoral tissue. Positron emission tomography (PET)-magnetic resonance imaging (MRI) is the problem-solving…
View article: Alzheimer’s disease is associated with increased modularity and assortativity: Evidence from structural and metabolic connectivity
Alzheimer’s disease is associated with increased modularity and assortativity: Evidence from structural and metabolic connectivity Open
Background Alzheimer’s disease (AD) is a progressive disorder associated with cognitive dysfunction that alters brain connectivity and assessing these altered connectivity patterns has become a topic of increasing interest. In this study, …
View article: A Rare Case of Asymmetric Progressive Supra Nuclear Palsy Diagnosed In vivo with Magnetic Resonance/Positron Emission Tomography
A Rare Case of Asymmetric Progressive Supra Nuclear Palsy Diagnosed In vivo with Magnetic Resonance/Positron Emission Tomography Open
PSP and CBD are usually multi system sporadic disorders characterized by tau inclusions in neurons and glia. The clinical and neuroimaging features are different .However in some cases overlapping of features are noted. Here we present a c…
View article: Resting-State Functional MRI/PET Profile as a Potential Alternative to Tri-Modality EEG-MR/PET Imaging: An Exploratory Study in Drug-Refractory Epilepsy
Resting-State Functional MRI/PET Profile as a Potential Alternative to Tri-Modality EEG-MR/PET Imaging: An Exploratory Study in Drug-Refractory Epilepsy Open
Objective The study explores whether the epileptic networks associate with predetermined seizure onset zone (SOZ) identified from other modalities such as electroencephalogram/video electroencephalogram/structural MRI (EEG/VEEG/sMRI) and w…
View article: Localisation of eloquent cortex using magnetoencephalography and its clinical implications
Localisation of eloquent cortex using magnetoencephalography and its clinical implications Open
This study aimed to localise the eloquent cortex and measure evoked field (EF) parameters using magnetoencephalography in patients with epilepsy and tumours near the eloquent cortex. A total of 41 patients (26 with drug-refractory epilepsy…
View article: Radiation Safety for Anesthesiologists and Other Personnel on Simultaneous PET/MRI: Possible Radiation Exposure from Patients While Performing Prolonged Duration Scans
Radiation Safety for Anesthesiologists and Other Personnel on Simultaneous PET/MRI: Possible Radiation Exposure from Patients While Performing Prolonged Duration Scans Open
This observational study was conducted owing to the challenges of the positron emission tomography/magnetic resonance imaging (PET/MRI) that requires longer duration scanning of radiopharmaceutical injected patient and added MRI environmen…
View article: Is Thalamic Lesion a Contributing Factor for Inappropriate Sexual Behavior in Older Adults with Cognitive Impairment?
Is Thalamic Lesion a Contributing Factor for Inappropriate Sexual Behavior in Older Adults with Cognitive Impairment? Open
Thalamus is a group of nuclei located deep inside the brain, well known for its sensory and cognitive functions. However, its role in the reward and behavior regulation is less explored. In this case series, we have presented four cases wi…
View article: Preliminary experience in a tertiary geriatric centre of PCASL as a potential biomarker in dementia imaging
Preliminary experience in a tertiary geriatric centre of PCASL as a potential biomarker in dementia imaging Open
Background PCASL is a perfusion imaging biomarker and is a contrast free , radiation free technique .At our tertiary neuropsychiatric centre MR/PETstudies had optimised and standardised PCASL sequence with gold standard FDG PET .In this st…
View article: Can High b Value Diffusion Be a Surrogate Marker for PET—A MR/PET Study in Neurooncology Set Up
Can High b Value Diffusion Be a Surrogate Marker for PET—A MR/PET Study in Neurooncology Set Up Open
Purpose: Hybrid whole-body magnetic resonance/positron emission tomography (MR/PET) systems are new diagnostic tools enabling the simultaneous acquisition of morphologic and multiparametric functional data, which allow for a diversified ch…
View article: Hydrocephalic Dementia: Revisited with Multimodality Imaging and toward a Unified Imaging Approach
Hydrocephalic Dementia: Revisited with Multimodality Imaging and toward a Unified Imaging Approach Open
Objective Overlap of normal pressure hydrocephalus (NPH) and pathology proven cases of dementia is known. The objective of this paper is to correlate both the clinical and multimodality imaging findings in patients with imaging diagnosis N…
View article: Hybrid PET/MRI findings in a case of pulmonary and extra-pulmonary tuberculosis associated with motor-neuron disease-like illness—a coincidence or a causation?: a case report
Hybrid PET/MRI findings in a case of pulmonary and extra-pulmonary tuberculosis associated with motor-neuron disease-like illness—a coincidence or a causation?: a case report Open
View article: Incremental Utility of Tc-99m Glucohepatonate Single-Photon Emission Computed Tomography over 18F-Flourodeoxyglucose Positron Emission Tomography in Diagnosis of Brain Tumor Recurrence – Old is Gold
Incremental Utility of Tc-99m Glucohepatonate Single-Photon Emission Computed Tomography over 18F-Flourodeoxyglucose Positron Emission Tomography in Diagnosis of Brain Tumor Recurrence – Old is Gold Open
Detection of recurrence of a brain tumor after treatment is one of the most important and challenging diagnostic problems in neuro-oncological practice. In spite of technical advances in imaging modalities, sometimes, certain clinical pres…
View article: Shape Profile of Corpus Callosum As a Signature to Phenotype Different Dementia
Shape Profile of Corpus Callosum As a Signature to Phenotype Different Dementia Open
Background Phenotyping dementia is always a complex task for a clinician. There is a need for more practical biomarkers to aid clinicians. Objective The aim of the study is to investigate the shape profile of corpus callosum (CC) in differ…
View article: A New Statistical Framework for Corpus Callosum Sub-Region Characterization Based on LBP Texture in Patients With Parkinsonian Disorders: A Pilot Study
A New Statistical Framework for Corpus Callosum Sub-Region Characterization Based on LBP Texture in Patients With Parkinsonian Disorders: A Pilot Study Open
Our result demonstrates the efficacy of proposed methodology in analyzing tissue alteration in MRI of Parkinsonian disorders and thus has potential to become valuable tool in computer aided differential diagnosis.
View article: P2‐380: A PICTORIAL REVIEW ON ROLE OF ASL IN VARIOUS NEURODEGENERATIVE DISORDERS: A SIMULTANEOUS MR‐PET STUDY
P2‐380: A PICTORIAL REVIEW ON ROLE OF ASL IN VARIOUS NEURODEGENERATIVE DISORDERS: A SIMULTANEOUS MR‐PET STUDY Open
To determine the patterns of cerebral blood flow changes in various neurodegenerative diseases. We present a pictorial review of various types of Dementia, Parkinsonian and PD plus disorders .The advantage of simultaneous PET MR is harness…
View article: Solving the riddle of “Idiopathic” in idiopathic intracranial hypertension and normal pressure hydrocephalus: An imaging study of the possible mechanisms – Monro–Kellie 3.0
Solving the riddle of “Idiopathic” in idiopathic intracranial hypertension and normal pressure hydrocephalus: An imaging study of the possible mechanisms – Monro–Kellie 3.0 Open
Background: Idiopathic intracranial hypertension (IIH) and normal pressure hydrocephalus (NPH) represent a cluster of typical clinical and imaging findings, with no evident etiological cause noted. In this study, we have proposed a model f…
View article: Tumefactive demyelination versus primary central nervous system lymphoma on <sup>18</sup>F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging: A twist in the tale
Tumefactive demyelination versus primary central nervous system lymphoma on <sup>18</sup>F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging: A twist in the tale Open
Demyelinating lesions of the central nervous system (CNS) are classically known to be hypometabolic on 18F-Flurodeoxyglucose Positron Emission Tomography (18F-FDG PET). However, demyelinating lesions may show increase…
View article: Role of Corpus Callosum Volumetry in Differentiating the Subtypes of Progressive Supranuclear Palsy and Early Parkinson's Disease
Role of Corpus Callosum Volumetry in Differentiating the Subtypes of Progressive Supranuclear Palsy and Early Parkinson's Disease Open
Background and Objective Progressive supranuclear palsy ( PSP ) is a progressive neurodegenerative disorder. Classic PSP or Richardson‐Steele phenotype ( PSP ‐ RS ) and parkinsonian phenotype ( PSP ‐P) are the common subtypes of PSP . At t…
View article: Can transcranial color doppler spectral signatures be a novel biomarker for monitoring cerebrovascular autoregulation and intracranial pressure? a speculative synthesis
Can transcranial color doppler spectral signatures be a novel biomarker for monitoring cerebrovascular autoregulation and intracranial pressure? a speculative synthesis Open
The sequential evolution of distinct patterns of Doppler waveform with increasing degree of raise in ICP has been described and can act as a quick screening tool in NICU and helps stratify patients for treatment and prognostication.
View article: Temporal Dynamics of the Default Mode Network Characterize Meditation-Induced Alterations in Consciousness
Temporal Dynamics of the Default Mode Network Characterize Meditation-Induced Alterations in Consciousness Open
Current research suggests that human consciousness is associated with complex, synchronous interactions between multiple cortical networks. In particular, the default mode network (DMN) of the resting brain is thought to be altered by chan…