Sandhya Matthes
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View article: From the infant to the geriatric patient—Strategies for inhalation therapy in asthma and chronic obstructive pulmonary disease
From the infant to the geriatric patient—Strategies for inhalation therapy in asthma and chronic obstructive pulmonary disease Open
Inhalation therapy represents the standard of care in children, adolescents as well as in young, middle‐aged and geriatric adults with asthma or chronic obstructive pulmonary disease. However, there are only few recommendations for the cho…
View article: Analysis of an Individualised Stepwise Approach to Non-Pharmacological Therapy in COVID-19
Analysis of an Individualised Stepwise Approach to Non-Pharmacological Therapy in COVID-19 Open
Background: Early intubation versus use of conventional or high-flow nasal cannula oxygen therapy (COT/HFNC), continuous positive airway pressure (CPAP), and non-invasive ventilation (NIV) has been debated throughout the COVID-19 pandemic.…
View article: Analysis of an individualised step-wise approach to non-pharmacological therapy in COVID-19 - Raw data
Analysis of an individualised step-wise approach to non-pharmacological therapy in COVID-19 - Raw data Open
Raw data set on which manuscript entitled " Analysis of an individualised step-wise approach to non-pharmacological therapy in COVID-19" is based on
View article: Assessment of sleep disordered breathing in patients with heart failure
Assessment of sleep disordered breathing in patients with heart failure Open
When to look for sleep disturbances in heart failure patients and how best to treat them: a practical and evidence-based expert opinion https://bit.ly/3LpCnNP.
View article: Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial
Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial Open
View article: High sensitivity of PD-L1 analysis from pleural effusion in nonsmall cell lung cancer
High sensitivity of PD-L1 analysis from pleural effusion in nonsmall cell lung cancer Open
Background: Programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) immune checkpoint inhibitors have been approved for monotherapy of metastatic nonsmall cell lung cancer (mNSCLC) depending on tumour cells' P…
View article: Diagnosis in interstitial lung disease: highly confident histopathological results from transbronchial cryobiopsy are reliable
Diagnosis in interstitial lung disease: highly confident histopathological results from transbronchial cryobiopsy are reliable Open
View article: Combining biopsy tools improves mutation detection rate in central lung cancer
Combining biopsy tools improves mutation detection rate in central lung cancer Open
In central exophytic lung cancer, the detection rate of oncogenic mutations and PDL1 positivity may be increased by combined sampling by forceps and EBUS-TBNA. The additional sampling of mediastinal lymph node and ctDNA may not be of ad…
View article: Vorschau: Chem. Ing. Tech. 12/2019
Vorschau: Chem. Ing. Tech. 12/2019 Open
View article: Asthma features in severe COPD: Identifying treatable traits
Asthma features in severe COPD: Identifying treatable traits Open
View article: Perception of climate change in patients with chronic lung disease
Perception of climate change in patients with chronic lung disease Open
Overall patients are more sensitive to health-related consequences of climate change. Yet, the hazard of heat-days seems underestimated and awareness should be raised.
View article: Acute Effects of Inspiratory Muscle Training on Pulmonary Arterial Pressure,Cardiac Output and Pulmonary Arterial Saturation Derived Oxygen Cost of Breathing
Acute Effects of Inspiratory Muscle Training on Pulmonary Arterial Pressure,Cardiac Output and Pulmonary Arterial Saturation Derived Oxygen Cost of Breathing Open
Respiration and respiratory maneuvers affect cardiac output. Inspiratory muscle training (IMT) increases the negative thoracic pressure, which could have an impact on intra-thoracic hemodynamics and thereby influence the cardiac output (CO…
View article: Comparing Azole Plasma Trough Levels in Lung Transplant Recipients: Percentage of Therapeutic Levels and Intrapatient Variability
Comparing Azole Plasma Trough Levels in Lung Transplant Recipients: Percentage of Therapeutic Levels and Intrapatient Variability Open
Background: This study compared therapeutic azole plasma trough levels (APL) of the azole antimycotics itraconazole (ITR), voriconazole (VOR), and posaconazole (POS) in lung transplant recipients and analyzed the influencing factors. In ad…
View article: Comparison of Transcutaneous and Capillary Measurement of P<sub>CO<sub>2</sub></sub> in Hypercapnic Subjects
Comparison of Transcutaneous and Capillary Measurement of P<sub>CO<sub>2</sub></sub> in Hypercapnic Subjects Open
Our study evaluated transcutaneous capnography as a continuous nocturnal measurement in hypercapnic subjects. We found a good agreement between the methods. Because CO2 is not constant in patients with respiratory failure, but instead fluc…