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View article: Intelligent Biosensors Based on Hyaluronic Acid Hydrogels for Monitoring Chronic Wound Healing with the Involvement of Artificial Intelligence
Intelligent Biosensors Based on Hyaluronic Acid Hydrogels for Monitoring Chronic Wound Healing with the Involvement of Artificial Intelligence Open
Chronic wounds, such as those caused by diabetes, burns, and pressure ulcers, pose significant healthcare challenges due to their slow healing and potential for infections. Traditional methods for monitoring wound healing are often intrusi…
View article: Heart‐focused breathing technique and attitude breathing technique effects on heart rate variability in young healthy subjects
Heart‐focused breathing technique and attitude breathing technique effects on heart rate variability in young healthy subjects Open
Heart rate variability (HRV) is controlled mainly by the autonomic nervous system (ANS). The aim of our prospective study was to investigate whether respiratory control influences changes in ANS activity, as reflected by HRV parameters. Th…
View article: The Molecular Interplay Between Oral Microbiome and Oral Cancer Pathogenesis
The Molecular Interplay Between Oral Microbiome and Oral Cancer Pathogenesis Open
The oral microbiome plays a key role in oral cancer pathogenesis through mechanisms such as chronic inflammation, dysregulated proliferation, and increased tumor invasiveness. Dysbiosis, frequently present in premalignant and malignant les…
View article: Rewiring the Brain Through the Gut: Insights into Microbiota–Nervous System Interactions
Rewiring the Brain Through the Gut: Insights into Microbiota–Nervous System Interactions Open
The gut-brain axis (GBA) represents an operant acting in a two-direction communication system between the gastrointestinal tract and the central nervous system, mediated by the enteric nervous system (ENS), vagus nerve, immune pathways, an…
View article: Pancreatic neuroendocrine tumors – going beyond surgery. Literature review and experience of a tertiary center
Pancreatic neuroendocrine tumors – going beyond surgery. Literature review and experience of a tertiary center Open
Background: Surgery is the standard therapy for pancreatic neuroendocrine tumors (pNETs), but since post-resection fistulae and other surgery related complications are common, new minimal invasive approaches are emerging. Endoscopic ultras…
View article: [18F]-FDG PET-CT in Malignant Melanoma
[18F]-FDG PET-CT in Malignant Melanoma Open
Background/Objectives: Malignant melanoma (MM) is an aggressive neoplasm with a rising global incidence. Accurate staging and risk stratification are essential for guiding therapeutic decisions and improving patient prognosis. [18F]-FDG PE…
View article: Overview of Adverse Reactions of Radiopharmaceuticals
Overview of Adverse Reactions of Radiopharmaceuticals Open
Radionuclide therapy offers a targeted approach that is a less invasive alternative to conventional treatments with a favorable safety profile. Continued evaluation of adverse reactions and the development of standardized ADR assessment to…
View article: Hypertriglyceridemia-Induced and Alcohol-Induced Acute Pancreatitis—A Severity Comparative Study
Hypertriglyceridemia-Induced and Alcohol-Induced Acute Pancreatitis—A Severity Comparative Study Open
Background: Alcohol use and hypertriglyceridemia are the second and third common causes of acute pancreatitis after choledocholithiasis. Still, few studies directly compare the severity and outcomes of these two groups, which share pathoph…
View article: Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania
Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients in Bucharest, Romania Open
Background and Objectives: This study aims to identify cardiovascular risk factors among 91 patients with multiple sclerosis in Bucharest, Romania, using data from medical records and a self-administered questionnaire. Materials and Method…
View article: Groove Pancreatitis in Focus: Tumor-Mimicking Phenotype, Diagnosis, and Management Insights
Groove Pancreatitis in Focus: Tumor-Mimicking Phenotype, Diagnosis, and Management Insights Open
Background/Objectives: Groove pancreatitis (GP) is an uncommon pancreatic condition implying a challenging differential diagnosis. This study aims to comprehensively evaluate the main risk factors, clinical presentation, imaging and endosc…
View article: Hepatocellular Carcinoma in Patients with Chronic Hepatitis C and Liver Cirrhosis Treated with DAA: A Focused Review
Hepatocellular Carcinoma in Patients with Chronic Hepatitis C and Liver Cirrhosis Treated with DAA: A Focused Review Open
Background/Objectives: The issue of HCC recurrence in patients with liver cirrhosis and chronic HCV infection after DAA treatment as well as the issue of de novo HCC in individuals with chronic HCV hepatitis treated with DAA is of great im…
View article: The Role of Nailfold Videocapillaroscopy in the Diagnosis and Monitoring of Interstitial Lung Disease Associated with Rheumatic Autoimmune Diseases
The Role of Nailfold Videocapillaroscopy in the Diagnosis and Monitoring of Interstitial Lung Disease Associated with Rheumatic Autoimmune Diseases Open
Interstitial lung disease (ILD) is a severe complication of certain connective tissue diseases (CTDs) such as systemic sclerosis (SSc), mixed connective tissue disease (MCTD), idiopathic inflammatory myopathies (IIM), rheumatoid arthritis …
View article: Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients
Unmasking the Silent Threat: Prevalence of Cardiovascular Risk Factors in MS Patients Open
This study aims to identify cardiovascular risk factors among 91 patients with multiple sclerosis in Bucharest, Romania, using data from medical records and a self-administered questionnaire. The research focuses on smoking status, body ma…
View article: The Impact of Hepatic Hydrothorax on the Outcome of Liver Cirrhosis: A Comparative Study
The Impact of Hepatic Hydrothorax on the Outcome of Liver Cirrhosis: A Comparative Study Open
Introduction: Hepatic hydrothorax (HH) is a severe cirrhosis complication requiring early diagnosis and appropriate management. This study aimed to assess the impact of HH on the disease severity and mortality of cirrhotic patients and com…
View article: Microbiota Involvement in Acute and Chronic Pancreatitis
Microbiota Involvement in Acute and Chronic Pancreatitis Open
The microbiota plays a significant role in the development, progression, and severity of both acute and chronic pancreatitis through mechanisms involving immune modulation, microbial translocation, and gut permeability. The intricate relat…
View article: The Role of Gut Microbiota in Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD)
The Role of Gut Microbiota in Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD) Open
Gut microbiota plays a critical role in developing and progressing metabolic dysfunction-associated steatotic liver disease (MASLD). Studies show reduced microbial diversity and specific shifts in bacterial populations in MASLD patients, w…
View article: Digestive Amyloidosis Trends: Clinical, Pathological, and Imaging Characteristics
Digestive Amyloidosis Trends: Clinical, Pathological, and Imaging Characteristics Open
Amyloidosis is a group of diseases characterized by the extracellular deposition of abnormally folded, insoluble proteins that lead to organ dysfunction. While it commonly affects the cardiovascular system, gastrointestinal (GI) tract invo…
View article: Eyes as Windows: Unveiling Neuroinflammation in Multiple Sclerosis via Optic Neuritis and Uhthoff’s Phenomenon
Eyes as Windows: Unveiling Neuroinflammation in Multiple Sclerosis via Optic Neuritis and Uhthoff’s Phenomenon Open
Background/Objectives: This study investigated the frequency and timing of optic neuritis (ON) episodes in relation to the onset of multiple sclerosis (MS) and examined the occurrence of Uhthoff’s phenomenon and Lhermitte’s sign to underst…
View article: Exploring the Relationship between Lipid Profile, Inflammatory State and 25-OH Vitamin D Serum Levels in Hospitalized Patients
Exploring the Relationship between Lipid Profile, Inflammatory State and 25-OH Vitamin D Serum Levels in Hospitalized Patients Open
Anomalies in lipid metabolism involve multifactorial pathogenesis, among other factors, being associated with an inflammatory state and disturbances in vitamin D status. The literature has focused on the binary relationships between inflam…
View article: Using the ClinFIT COVID-19 Instrument to Assess the Functional Impairments Specific to Post-COVID-19 Patients in Romania
Using the ClinFIT COVID-19 Instrument to Assess the Functional Impairments Specific to Post-COVID-19 Patients in Romania Open
Introduction: The COVID-19 pandemic has led to approximately 3.5 million cases in Romania, causing systemic inflammation and over 200 symptoms affecting various body systems. This complexity has challenged rehabilitation systems, necessita…
View article: Prosthetic Valve Endocarditis: A Retrospective Cohort Study Conducted at “Dr. Carol Davila” Central Military Emergency University Hospital in Bucharest
Prosthetic Valve Endocarditis: A Retrospective Cohort Study Conducted at “Dr. Carol Davila” Central Military Emergency University Hospital in Bucharest Open
Objective: To evaluate patients with prosthetic valves who developed infective endocarditis by comparing treatment outcomes in both early- and late-onset IE episodes following prosthetic valve replacement surgery. This study sought to cond…
View article: Prosthetic Valve Endocarditis: A Retrospective Cohort Study Conducted at “Dr. <span aria-describedby="tippy-46">Carol Davila” Central Military Emergency University Hospital in Bucharest
Prosthetic Valve Endocarditis: A Retrospective Cohort Study Conducted at “Dr. <span>Carol Davila” Central Military Emergency University Hospital in Bucharest Open
Objective: Evaluation of patients with prosthetic valves who developed infective endocarditis by comparing treatment outcomes in both early- and late-onset IE episodes following prosthetic valve replacement surgery. This study sought to co…
View article: Intraoperative Oxygen Consumption and Postoperative Immune Response in Colorectal Oncological Surgery: A Prospective, Monocentric Pilot Study
Intraoperative Oxygen Consumption and Postoperative Immune Response in Colorectal Oncological Surgery: A Prospective, Monocentric Pilot Study Open
Surgical resection is the key treatment for colorectal cancer, but the extent of surgical trauma has been implied as a key factor for the oncologic outcome. The immune stress response to surgical trauma generates a cascade of immunological…
View article: Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease—Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease—Clinical and Pre-Clinical Overview and Systematic Review of the Literature Open
Non-alcoholic fatty liver disease (NAFLD) is the predominant cause of chronic liver conditions, and its progression is marked by evolution to non-alcoholic steatosis, steatohepatitis, cirrhosis related to non-alcoholic steatohepatitis, and…
View article: Correlation between Trabecular Bone Score and Homocysteine Level in Rheumatoid Arthritis Patients on Anti-TNF Inhibitors
Correlation between Trabecular Bone Score and Homocysteine Level in Rheumatoid Arthritis Patients on Anti-TNF Inhibitors Open
Rheumatoid arthritis (RA) is an independent osteoporosis risk factor. Biologic and immunosuppressive treatment, and levels of homocysteine and 25-OH vitamin D may influence the trabecular bone score (TBS) in RA patients. We aimed to compar…
View article: The Spectrum of Neurological Complications after Bariatric Surgery – Review of the Literature
The Spectrum of Neurological Complications after Bariatric Surgery – Review of the Literature Open
Bariatric surgery represents one of the most efficient treatments addressing obesity and its associated complications with an increasing trend. Even if the medical benefits for patients are huge, due to weight loss and despite technical im…
View article: Role of Cannabinoids in Oral Cancer
Role of Cannabinoids in Oral Cancer Open
Cannabinoids have incited scientific interest in different conditions, including malignancy, due to increased exposure to cannabis. Furthermore, cannabinoids are increasingly used to alleviate cancer-related symptoms. This review paper aim…
View article: Ferritin and Ferritin-to-Hemoglobin Ratio as Promising Prognostic Biomarkers of Severity in Acute Pancreatitis—A Cohort Study
Ferritin and Ferritin-to-Hemoglobin Ratio as Promising Prognostic Biomarkers of Severity in Acute Pancreatitis—A Cohort Study Open
Background: Acute pancreatitis is an inflammation of the pancreas with variable outcomes depending on its severity. Multiple systems of prediction have been proposed, each with variable specificity and sensitivity and with uneven clinical …
View article: Estrobolome and Hepatocellular Adenomas—Connecting the Dots of the Gut Microbial β-Glucuronidase Pathway as a Metabolic Link
Estrobolome and Hepatocellular Adenomas—Connecting the Dots of the Gut Microbial β-Glucuronidase Pathway as a Metabolic Link Open
Hepatocellular adenomas are benign endothelial tumors of the liver, mostly associated with female individual users of estrogen-containing medications. However, the precise factors underlying the selective development of hepatic adenomas in…
View article: Golgi Apparatus Target Proteins in Gastroenterological Cancers: A Comprehensive Review of GOLPH3 and GOLGA Proteins
Golgi Apparatus Target Proteins in Gastroenterological Cancers: A Comprehensive Review of GOLPH3 and GOLGA Proteins Open
The Golgi apparatus plays a central role in protein sorting, modification and trafficking within cells; its dysregulation has been implicated in various cancers including those affecting the GI tract. This review highlights two Golgi targe…