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View article: Prenatal and childhood exposure to mixtures of environmental chemicals and adolescence attentional problems: a triangulation study
Prenatal and childhood exposure to mixtures of environmental chemicals and adolescence attentional problems: a triangulation study Open
Triangulation of multiple causal designs suggests that childhood exposure to the OPP metabolite DEP may impair adolescent attentional function.
View article: Effect of Urban Infrastructure on Physical Activity and Health Indicators: The Case of the City of Kaunas, Lithuania
Effect of Urban Infrastructure on Physical Activity and Health Indicators: The Case of the City of Kaunas, Lithuania Open
Urban infrastructure is a key determinant of population health and physical activity. Well-planned environments support active lifestyles and reduce health risks. This study examined the relationship between urban infrastructure, physical …
View article: Associations of family affluence with cortisol production and telomere length in European children
Associations of family affluence with cortisol production and telomere length in European children Open
UK Research and Innovation (Grants: MR/S03532X/1, MR/Y02012X/1), European Community (Grants: 874583, 308333).
View article: Outdoor air pollution, road traffic noise, and allostatic load in children aged 6–11 years: evidence from six European cohorts
Outdoor air pollution, road traffic noise, and allostatic load in children aged 6–11 years: evidence from six European cohorts Open
Emerging evidence suggests that exposure to air pollutants and road traffic noise triggers stress responses, which mediate physiological responses in multiple organs and tissues. However, epidemiological study in children is sparse. We aim…
View article: Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium
Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium Open
Background DNA methylation (DNAm) is a developmentally dynamic epigenetic process; yet, most epigenome-wide association studies (EWAS) have examined DNAm at only one timepoint or without systematic comparisons between timepoints. Thus, it …
View article: Telomere Length and Symptoms of Attention Deficit and Hyperactivity Disorder in Children at 6–12 Years
Telomere Length and Symptoms of Attention Deficit and Hyperactivity Disorder in Children at 6–12 Years Open
Objective: To explore the association between telomere length (TL) and attention deficit hyperactivity disorder (ADHD) symptoms in children at 6–12 years. Method: Data from 1,759 children belonging to the HELIX project cohorts and the Astu…
View article: Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants
Multi-omics architecture of childhood obesity and metabolic dysfunction uncovers biological pathways and prenatal determinants Open
Childhood obesity poses a significant public health challenge, yet the molecular intricacies underlying its pathobiology remain elusive. Leveraging extensive multi-omics profiling (methylome, miRNome, transcriptome, proteins and metabolite…
View article: Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children
Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children Open
Importance Prenatal exposure to ubiquitous endocrine-disrupting chemicals (EDCs) may increase the risk of metabolic syndrome (MetS) in children, but few studies have studied chemical mixtures or explored underlying protein and metabolic si…
View article: Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium
Epigenetic timing effects on child developmental outcomes: A longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium Open
DNA methylation (DNAm) is a developmentally dynamic epigenetic process, yet we still know little about how epigenetic effects on health outcomes vary over time; whether DNAm alterations during certain periods of development are more inform…
View article: Common genetic variants associated with urinary phthalate levels in children: a genome-wide study
Common genetic variants associated with urinary phthalate levels in children: a genome-wide study Open
Introduction Phthalates, or dieters of phthalic acid, are a ubiquitous type of plasticizer used in a variety of common consumer and industrial products. They act as endocrine disruptors and are associated with increased risk for several di…
View article: Corrigendum to “In-utero and childhood chemical exposome in six European mother-child cohorts” [Environ. Int. 121(Part 1) (2018) 751–763]
Corrigendum to “In-utero and childhood chemical exposome in six European mother-child cohorts” [Environ. Int. 121(Part 1) (2018) 751–763] Open
The authors regret that in the original research paper entitled “In-utero and childhood chemical exposome in six European mother-child cohorts” published in Environment International 121 (2018) 751–763, the lipid adjustments for POPs (i.e.…
View article: Implementing co-created citizen science in five environmental epidemiological studies in the CitieS-Health project
Implementing co-created citizen science in five environmental epidemiological studies in the CitieS-Health project Open
Integration of co-created citizen science in environmental epidemiology is feasible and has the potential to improve the quality of research whilst promoting civic trust in research and results.
View article: Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort
Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort Open
Background: While biological age in adults is often understood as representing general health and resilience, the conceptual interpretation of accelerated biological age in children and its relationship to development remains unclear. We a…
View article: Author response: Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort
Author response: Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort Open
Full text Figures and data Side by side Abstract Editor's evaluation eLife digest Introduction Materials and methods Results Discussion Data availability References Decision letter Author response Article and author information Metrics Abs…
View article: Toolkit for conducting citizen science activities in environmental epidemiology
Toolkit for conducting citizen science activities in environmental epidemiology Open
Scientists and practitioners implementing citizen science projects, in which the involvement of citizens is key, often need ideas and tools that help in reaching citizens, engaging them in the project and maximizing their contributions. In…