Sandra E. Juul
YOU?
Author Swipe
View article: Connecting Teachers – Changing from Within
Connecting Teachers – Changing from Within Open
The 2024 Lund University Conference on Teaching and Learning, hosted by MedCUL and the Division for Higher Education Development (AHU), took place in the newly inaugurated Forum Medicum – an environment purposefully designed to inspire con…
View article: Bowel function and quality of life in adolescents with Hirschsprung disease
Bowel function and quality of life in adolescents with Hirschsprung disease Open
Persistent functional bowel problems are common among HD adolescents, yet their generic QoL remains satisfactory. Given that bowel issues are associated with lower generic QoL, effective management of bowel problems appears essential for m…
View article: Ferreting Out the Effects of Neonatal Hypoxia–Ischemia and Sex on Ferret Cortical Gyrification
Ferreting Out the Effects of Neonatal Hypoxia–Ischemia and Sex on Ferret Cortical Gyrification Open
Gyrification, the folding of the cerebral cortex, plays a crucial role in brain development and function. Perinatal hypoxia–ischemia (HI) is a leading cause of neonatal brain injury, affecting cortical folding that can be measured by the g…
View article: Multi‐modal screening for synergistic neuroprotection of mild extremely preterm brain injury
Multi‐modal screening for synergistic neuroprotection of mild extremely preterm brain injury Open
Preterm brain injury affects both white and gray matter, including altered cortical development and gyrification, with associated neurodevelopmental sequelae such as cerebral palsy and learning deficits. The preterm brain also displays reg…
View article: Childhood Differences in Healthcare Utilization Between Extremely Preterm Infants and the General Population
Childhood Differences in Healthcare Utilization Between Extremely Preterm Infants and the General Population Open
Background/Objective(s): Post-discharge clinical needs of extremely preterm (EP) infants are not well defined. The aim of this study is to evaluate healthcare utilization after discharge in infants born EP and compare it to the general ped…
View article: Multi-modal screening for synergistic neuroprotection of extremely preterm brain injury
Multi-modal screening for synergistic neuroprotection of extremely preterm brain injury Open
Summary Preterm brain injury affects both white and grey matter, including altered cortical development and gyrification, with associated neurodevelopmental sequelae such as cerebral palsy and learning deficits. The preterm brain also disp…
View article: Granular cytoplasmic inclusions in astrocytes and microglial activation in the fetal brain of pigtail macaques in response to maternal viral infection
Granular cytoplasmic inclusions in astrocytes and microglial activation in the fetal brain of pigtail macaques in response to maternal viral infection Open
View article: Predictors of Death or Severe Impairment in Neonates With Hypoxic-Ischemic Encephalopathy
Predictors of Death or Severe Impairment in Neonates With Hypoxic-Ischemic Encephalopathy Open
Importance Outcomes after hypoxic-ischemic encephalopathy (HIE) are variable. Predicting death or severe neurodevelopmental impairment (NDI) in affected neonates is crucial for guiding management and parent communication. Objective To pred…
View article: Assessing Early Severity of Hypoxic-Ischemic Encephalopathy: The Role of Electroencephalogram Background in Addition to Sarnat Exam
Assessing Early Severity of Hypoxic-Ischemic Encephalopathy: The Role of Electroencephalogram Background in Addition to Sarnat Exam Open
View article: Perinatal arterial ischemic stroke diagnosed in infants receiving therapeutic hypothermia for hypoxic-ischemic encephalopathy
Perinatal arterial ischemic stroke diagnosed in infants receiving therapeutic hypothermia for hypoxic-ischemic encephalopathy Open
Background Both perinatal arterial ischemic stroke (PAIS) and hypoxic-ischemic encephalopathy (HIE) can present with neonatal encephalopathy. We hypothesized that among infants undergoing therapeutic hypothermia, presence of PAIS is associ…
View article: Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neonatal Neurocritical Care, seizures, and continuous aEEG and /or EEG monitoring
Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neonatal Neurocritical Care, seizures, and continuous aEEG and /or EEG monitoring Open
Preterm children are at risk for language development delays. Early shared reading has been demonstrated to enhance language development and functional brain connectivity in full-term
\nchildren. Therefore, recent research examines the pot…
View article: Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neuroprotection strategies in the neonate
Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Neuroprotection strategies in the neonate Open
BACKGROUND: Cerebral intraventricular hemorrhage (IVH) is a major cause of neurodevelopmental impairment in preterm infants.IVH is characterized by vessel rupture and a rapid accumulation of blood within the ventricles.Subsequent hemolysis…
View article: Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Long-term outcome studies, developmental care, palliative care, ethical dilemmas, and challenging clinical scenarios in neonatal neurology
Proceedings of the 15 <sup>th</sup> International Newborn Brain Conference: Long-term outcome studies, developmental care, palliative care, ethical dilemmas, and challenging clinical scenarios in neonatal neurology Open
BACKGROUND: Preterm birth is associated with significant risks for long-term impairments in brain structure and cognitive functions (1). At the microscopic level, the transient inflammatory and hypoxic-ischemic events occurring during prem…
View article: Artificial Intelligence Outcome Prediction in Neonates with Encephalopathy (AI-OPiNE)
Artificial Intelligence Outcome Prediction in Neonates with Encephalopathy (AI-OPiNE) Open
Purpose To develop a deep learning algorithm to predict 2-year neurodevelopmental outcomes in neonates with hypoxic-ischemic encephalopathy using MRI and basic clinical data. Materials and Methods In this study, MRI data of term neonates w…
View article: Early and extended erythropoietin monotherapy after hypoxic ischaemic encephalopathy: a multicentre double-blind pilot randomised controlled trial
Early and extended erythropoietin monotherapy after hypoxic ischaemic encephalopathy: a multicentre double-blind pilot randomised controlled trial Open
Objective To examine the feasibility of early and extended erythropoietin monotherapy after hypoxic ischaemic encephalopathy (HIE). Design Double-blind pilot randomised controlled trial. Setting Eight neonatal units in South Asia. Patients…
View article: Table of Contents
Table of Contents Open
View article: Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy
Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy Open
View article: Relationship of Neonatal Seizure Burden Before Treatment and Response to Initial Antiseizure Medication
Relationship of Neonatal Seizure Burden Before Treatment and Response to Initial Antiseizure Medication Open
Maximal seizure burden may be more important than other, more commonly used measures in predicting response to acute seizure treatments.
View article: Incidence, Risk Factors, and Outcomes Associated With Recurrent Neonatal Acute Kidney Injury in the AWAKEN Study
Incidence, Risk Factors, and Outcomes Associated With Recurrent Neonatal Acute Kidney Injury in the AWAKEN Study Open
Importance The incidence and associated outcomes of recurrent acute kidney injury (rAKI) in neonates remain largely unknown. Objective To determine the incidence, risk factors, and clinical outcomes associated with rAKI in critically ill n…
View article: Esophageal Versus Rectal Temperature Monitoring During Whole-Body Therapeutic Hypothermia for Hypoxic–Ischemic Encephalopathy: Association with Short- and Long-Term Outcomes
Esophageal Versus Rectal Temperature Monitoring During Whole-Body Therapeutic Hypothermia for Hypoxic–Ischemic Encephalopathy: Association with Short- and Long-Term Outcomes Open
View article: Yoga in the Neonatal Intensive Care Unit for parents: a needs assessment and acceptability study
Yoga in the Neonatal Intensive Care Unit for parents: a needs assessment and acceptability study Open
Aim: To explore NICU parent and staff attitudes towards yoga for parents as a stress reduction intervention and determine the acceptability of an online yoga curriculum. Methods: A 13-item survey on yoga for parents was emailed to clinical…
View article: Platelet Transfusion and Death or Neurodevelopmental Impairment in Children Born Extremely Preterm
Platelet Transfusion and Death or Neurodevelopmental Impairment in Children Born Extremely Preterm Open
Importance Infants born extremely preterm receive transfusions at higher platelet count thresholds than older children and adults due to concerns for intracranial hemorrhage. A recent randomized trial comparing 2 platelet transfusion thres…
View article: Contemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age
Contemporary definitions of infant growth failure and neurodevelopmental and behavioral outcomes in extremely premature infants at two years of age Open
Background Associations of 2-year neurodevelopmental and behavioral outcomes with growth trajectories of preterm infants are unknown. Methods This secondary analysis of a preterm cohort examined in-hospital and discharge to 2-year changes …
View article: Neuroprotective therapies in the NICU in preterm infants: present and future (Neonatal Neurocritical Care Series)
Neuroprotective therapies in the NICU in preterm infants: present and future (Neonatal Neurocritical Care Series) Open
View article: Correction: Advancing brain MRI as a prognostic indicator in hypoxic-ischemic encephalopathy
Correction: Advancing brain MRI as a prognostic indicator in hypoxic-ischemic encephalopathy Open
View article: Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial
Darbepoetin alfa to reduce transfusion episodes in infants with haemolytic disease of the fetus and newborn who are treated with intrauterine transfusions in the Netherlands: an open-label, single-centre, phase 2, randomised, controlled trial Open
View article: Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial
Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial Open
Objective To study the association between the Sarnat exam (SE) performed before and after therapeutic hypothermia (TH) and outcomes at 2 years in infants with moderate or severe hypoxic-ischaemic encephalopathy (HIE). Design Secondary ana…
View article: Time to Reaching Target Cooling Temperature and 2-year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy
Time to Reaching Target Cooling Temperature and 2-year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy Open
View article: Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates
Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates Open
View article: Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial
Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial Open
Introduction: Erythropoietin (Epo) is a putative neuroprotective therapy that did not improve overall outcomes in a phase 3 randomized controlled trial for neonates with moderate or severe hypoxic-ischemic encephalopathy (HIE). However, HI…