Sandra Loss
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Higher Contrast in <sup>1</sup>H‐Observed NMR Ligand Screening with the PEARLScreen Experiment Open
For initial hit identification in fragment‐based drug design, NMR is one of the preferred methods, with the well‐established ligand screening experiments T 1ρ , waterLOGSY and STD. Here, we present a new, perfect echo‐based experiment with…
Small intestinal strangulation in 60 cattle – clinical, laboratory and ultrasonographic findings, treatment and outcome Open
Background Intestinal strangulation is constriction of the intestine by a band of tissue, ligament or blood vessel causing partial or complete intestinal obstruction. This retrospective study describes the clinical, laboratory and ultrason…
Fragment Screening and Fast Micromolar Detection on a Benchtop NMR Spectrometer Boosted by Photoinduced Hyperpolarization Open
Fragment‐based drug design is a well‐established strategy for rational drug design, with nuclear magnetic resonance (NMR) on high‐field spectrometers as the method of reference for screening and hit validation. However, high‐field NMR spec…