Sandra Okala
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Retrospective chart review of transplant recipients with cytomegalovirus infection who received maribavir in the Phase 3 SOLSTICE trial: Data at 52 weeks post-maribavir treatment initiation Open
Background Cytomegalovirus (CMV) infection is a frequent complication in haematopoietic cell/solid organ transplant (HCT/SOT) recipients. Previous studies report all-cause mortality rates of 31% and 50% in HCT/SOT recipients post-treatment…
Impact of Maternal Nutritional Supplementation during Pregnancy and Lactation on the Infant Gut or Breastmilk Microbiota: A Systematic Review Open
Recent evidence indicates that maternal dietary intake, including dietary supplements, during pregnancy and lactation may alter the infant gut or breastmilk microbiota, with implications for health outcomes in both the mother and infant. T…
Maternal plasma lipid levels across pregnancy and the risks of small-for-gestational age and low birth weight: a cohort study from rural Gambia Open
Background Sub-optimal maternal lipid levels during pregnancy may be implicated in the pathophysiological mechanisms leading to low birth weight (LBW) and small-for-gestational-age (SGA). We aimed to determine whether maternal lipid levels…
Impact of nutritional supplementation during pregnancy on antibody responses to diphtheria-tetanus-pertussis vaccination in infants: A randomised trial in The Gambia Open
ISRCTN49285450.
View article: P681 Importation of ciprofloxacin resistant<i>neisseria gonorrhoeae</i>into the UK: a public health challenge
P681 Importation of ciprofloxacin resistant<i>neisseria gonorrhoeae</i>into the UK: a public health challenge Open
Background Current UK guidelines for managing Neisseria gonorrhoeae (NG) infection include ciprofloxacin use if antimicrobial susceptibility is indicated, but this option would be less useful if ciprofloxacin resistant NG (CpR-NG) rates in…
Experiences of stigma and discrimination in social and healthcare settings among trans people living with HIV in the UK Open
The People Living with HIV StigmaSurvey UK 2015 was a community led national survey investigating experiences of people living with HIV in the UK in the past 12 months. Participants aged 18 and over were recruited through over 120 cross-se…
O12.2 Co-infection and macrolide antimicrobial resistance (AMR) of<i>mycoplasma genitalium</i>with<i>neisseria gonorrhoeae</i>and<i>chlamydia trachomatis</i>, in females, heterosexual males, and men-who-have-sex-with-men Open
Introduction Population-based prevalence estimates of Mycoplasma genitalium (MG), Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in men and women in England are: 1.2% and 1.3%; 1.1% and 1.5%; and <0.1%, respectively. In sexual h…
P206 Prevalence and risk factors associated with chlamydia trachomatis (CT), mycoplasma genitalium (MG) and neisseria gonorrhoeae(NG): cross-sectional study in three sexual health clinics Open
Introduction Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), and Neisseria gonorrhoeae (NG) infections contribute to major reproductive health sequelae. CT and NG are routinely tested for in sexual health clinics (SHCs), whereas MG…
P007 Effective clinical designs of multiplex point-of-care-tests for genital discharge syndrome management in women: which pathogen combinations and testing protocols deliver the best outcomes? Open
Introduction Syndromic management of sexually transmitted infections (STIs) is common practice in sexual health clinics (SHC). Implementation of multi-pathogen point-of-care-tests (POCTs) can improve patient management by providing same da…
The impact of isotype and structure on antibody-HIV interaction Open
Broadly neutralising antibodies that are capable of blocking HIV-1 infection at the mucosal portal of viral entry are probably the most researched types of antibodies. Both IgG and IgA antibodies are present in genital and rectal mucosal s…
P170 Risk factors for<i>Mycoplasma genitalium</i>infection in symptomatic males, females and men who have sex with men from three clinical settings in London: Abstract P170 Table 1 Open
Background/introduction Mycoplasma genitalium (MG), a sexually transmitted infection (STI), is increasingly recognised as a cause of major reproductive health sequelae. Treatment has become increasingly difficult due to macrolide and fluor…
P169 Comparison of the FTD™ Urethritis Plus (7-Plex) detection kit with routine sexual health clinic nucleic acid amplification testing for detection of<i>Neisseria gonorrhoeae</i>and<i>Chlamydia trachomatis</i>in urine, vaginal, pharyngeal and rectal samples: Abstract P169 Table 1 Open
Background/introduction The FTD™ Urethritis Plus (FTDU) nucleic acid amplification test (NAAT) detects seven pathogens associated with urethritis, including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplasma genitalium, Tri…