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View article: Le granule homéopathique imprégné conserve toute l’activité biologique d’Arnica montana. Effets sur des marqueurs inflammatoires in vitro
Le granule homéopathique imprégné conserve toute l’activité biologique d’Arnica montana. Effets sur des marqueurs inflammatoires in vitro Open
Few basic research studies have explored the biological effects of dissolved homeopathic granules, as most existing work uses water-based dilutions. This study aims to show that homeopathic dilutions retain their biological activity when g…
View article: Arnica montana: Anti-inflammatory properties in various cell models
Arnica montana: Anti-inflammatory properties in various cell models Open
Background: Arnica montana L. is a medicinal plant traditionally used to reduce inflammation, pain and swelling associated with trauma, and post-operative clinical conditions. However, the mechanism of action of homeopathic dilutions remai…
View article: Anas barbariae 200K Modulates Cell Stiffness and Oxidative Stress in Microglial Cells In Vitro
Anas barbariae 200K Modulates Cell Stiffness and Oxidative Stress in Microglial Cells In Vitro Open
Anas barbariae 200K, a homeopathic medicine, is traditionally used for influenza-like illnesses. We investigated the effects of Anas barbariae 200K on microglial cells, a subpopulation of macrophages specific to the central nervous system …
View article: <em>Influenzinum</em> and <em>Echinacea</em>: boosters of immune response in vitro
<em>Influenzinum</em> and <em>Echinacea</em>: boosters of immune response in vitro Open
Background: Some homeopathic medicines are traditionally used in medical practice to strengthen immunity and reduce inflammation. In particular, Influenzinum is used in clinical practice for the prevention of influenza-like illness, the ma…
View article: Anti-oxidant Effect of High Dilutions of <i>Arnica montana</i>, <i>Arsenicum Album,</i> and <i>Lachesis Mutus</i> in Microglial Cells <i>in Vitro</i>
Anti-oxidant Effect of High Dilutions of <i>Arnica montana</i>, <i>Arsenicum Album,</i> and <i>Lachesis Mutus</i> in Microglial Cells <i>in Vitro</i> Open
Microglial cells play important roles in inflammatory responses. The level of oxidative stress is a well-known marker of inflammation. Homeopathic medicines are often used clinically to alleviate inflammation. We evaluated the anti-oxidati…
View article: Molecular basis for intestinal mucin recognition by galectin‐3 and C‐type lectins
Molecular basis for intestinal mucin recognition by galectin‐3 and C‐type lectins Open
Intestinal mucins trigger immune responses upon recognition by dendritic cells via protein–carbohydrate interactions. We used a combination of structural, biochemical, biophysical, and cell‐based approaches to decipher the specificity of t…
View article: Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus Open
Ruminococcus gnavus is a human gut symbiont wherein the ability to degrade mucins is mediated by an intramolecular trans -sialidase ( Rg NanH). Rg NanH comprises a GH33 catalytic domain and a sialic acid-binding carbohydrate-binding module…
View article: Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives
Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives Open
Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases). A facile one-pot two-enzyme approach has been established for …