Sanjay V. Neerukonda
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View article: Dexamethasone Use in Pediatric Neurosurgical Trauma: A Systematic Review and Proportional Meta-Analysis of the Current Literature
Dexamethasone Use in Pediatric Neurosurgical Trauma: A Systematic Review and Proportional Meta-Analysis of the Current Literature Open
Study Design: Systematic Review with Proportional Meta-Analysis Objectives: Dexamethasone use in pediatric neurosurgical trauma remains controversial, with varying reports of its overall efficacy. Our study aims to assess the use of dexame…
View article: Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies
Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies Open
Persistent hyperactivity of nociceptors is known to contribute significantly to long-lasting sensitization and ongoing pain in many clinical conditions. It is often assumed that nociceptor hyperactivity is mainly driven by continuing stimu…
View article: Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies
Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies Open
Persistent hyperactivity of nociceptors is known to contribute significantly to long-lasting sensitization and ongoing pain in many clinical conditions. It is often assumed that nociceptor hyperactivity is mainly driven by continuing stimu…
View article: A differential of the left eye and right eye neurological pupil index is associated with discharge modified Rankin scores in neurologically injured patients
A differential of the left eye and right eye neurological pupil index is associated with discharge modified Rankin scores in neurologically injured patients Open
Background Automated infrared pupillometry (AIP) and the Neurological Pupil index (NPi) provide an objective means of assessing and trending the pupillary light reflex (PLR) across a broad spectrum of neurological diseases. NPi quantifies …
View article: Automated Pupillometry Value Differences Serve as a Prognostic Indicator Even When They are Within Normal Range
Automated Pupillometry Value Differences Serve as a Prognostic Indicator Even When They are Within Normal Range Open
Introduction. The pupillary light reflex (PLR) is an integral aspect of the neurologic exam. With the enhancement of automated infrared pupillometry (AIP), the Neurological Pupil index (NPi) is being increasingly used when performing a neu…
View article: A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets Open
Single-cell gene expression analysis predicts pain signaling pathways between sensory neurons and peripheral cell types.
View article: A pharmacological interactome platform for discovery of pain mechanisms and targets
A pharmacological interactome platform for discovery of pain mechanisms and targets Open
Cells communicate with each other through ligand and receptor interactions. In the case of the peripheral nervous system, these ligand-receptor interactions shape sensory experience. In disease states, such as chronic pain, these ligand-re…