Sanjun Cai
YOU?
Author Swipe
View article: Evaluating the role of glutathione reductase in aspartame-induced liver hepatocellular carcinoma: A molecular network and prognostic approach
Evaluating the role of glutathione reductase in aspartame-induced liver hepatocellular carcinoma: A molecular network and prognostic approach Open
This study aims to elucidate the molecular mechanisms underlying aspartame-associated liver hepatocellular carcinoma (LIHC) by identifying glutathione reductase (GSR) as a key molecular target. Through a combination of network toxicology a…
View article: Deciphering metabolic reprogramming of immune cells within the tumor microenvironment
Deciphering metabolic reprogramming of immune cells within the tumor microenvironment Open
View article: Transcranial direct current stimulation enhances the efficacy of wearable transcutaneous electrical nerve stimulation for mild knee osteoarthritis in the middle-aged person: a randomized controlled trial
Transcranial direct current stimulation enhances the efficacy of wearable transcutaneous electrical nerve stimulation for mild knee osteoarthritis in the middle-aged person: a randomized controlled trial Open
View article: Machine learning combined with multi-omics to identify immune-related LncRNA signature as biomarkers for predicting breast cancer prognosis
Machine learning combined with multi-omics to identify immune-related LncRNA signature as biomarkers for predicting breast cancer prognosis Open
This study developed an immune-related long non-coding RNAs (lncRNAs)-based prognostic signature by integrating multi-omics data and machine learning algorithms to predict survival and therapeutic responses in breast cancer patients. Utili…
View article: Synergistic Effects of Organic and Chemical Fertilizers on Microbial-Mediated Carbon Stabilization: Insights from Metagenomics and Spectroscopy
Synergistic Effects of Organic and Chemical Fertilizers on Microbial-Mediated Carbon Stabilization: Insights from Metagenomics and Spectroscopy Open
Fertilization management constitutes a critical determinant of agroecosystem productivity. Reasonable fertilization can increase the organic matter content in soil; however, the potential mechanism of how different fertilization regimes im…
View article: Downregulation of ferroptosis-related Genes can regulate the invasion and migration of osteosarcoma cells
Downregulation of ferroptosis-related Genes can regulate the invasion and migration of osteosarcoma cells Open
View article: Metagenomics Reveals the Effects of Organic Material Co-Application on Phosphorus Cycling Functional Genes and Bioavailable Phosphorus
Metagenomics Reveals the Effects of Organic Material Co-Application on Phosphorus Cycling Functional Genes and Bioavailable Phosphorus Open
Phosphorus is essential for crop growth, but excessive use of chemical fertilizers can lead to environmental issues. The incorporation of organic materials has the potential to enhance phosphorus availability and promote soil phosphorus cy…
View article: The knowledge, attitude and practice of nurses on the posture management of premature infants: status quo and coping strategies
The knowledge, attitude and practice of nurses on the posture management of premature infants: status quo and coping strategies Open
Neonatal nurses attach great importance to the posture management of premature infants, but their knowledge and skills need to be improved, and there are many related influencing factors. Nursing managers should strengthen the training rel…
View article: Investigate the Efficacy of Dual‐Target Electrical Stimulation in the Treatment of Knee Osteoarthritis After Stroke and its Effect on Cerebral Cortical Activity: A Randomized Controlled Trial
Investigate the Efficacy of Dual‐Target Electrical Stimulation in the Treatment of Knee Osteoarthritis After Stroke and its Effect on Cerebral Cortical Activity: A Randomized Controlled Trial Open
Transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) are both recognized for their analgesic effects; however, evidence suggests limitations in their efficacy when applied to knee osteoarthr…
View article: Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus
Self-healing hydrogels loaded with Spatholobi Caulis alleviate disc degeneration by promoting autophagy in nucelus pulposus Open
View article: EP11.03-41 Successful Treatment with Pembrolizumab Alone for SMARCA4-deficient Lung Sarcomatoid with a High-TMB and PD-L1(+) A Case Report
EP11.03-41 Successful Treatment with Pembrolizumab Alone for SMARCA4-deficient Lung Sarcomatoid with a High-TMB and PD-L1(+) A Case Report Open
View article: Definitive carbon ion re-irradiation with pencil beam scanning in the treatment of unresectable locally recurrent rectal cancer
Definitive carbon ion re-irradiation with pencil beam scanning in the treatment of unresectable locally recurrent rectal cancer Open
This study aimed to evaluate the oncological outcomes and safety of carbon ion re-irradiation with pencil beam scanning (PBS) delivery technique for previously irradiated and unresectable locally recurrent rectal cancer (LRRC). Between Jun…
View article: Clinical evaluation of a multitarget fecal immunochemical test‐sDNA test for colorectal cancer screening in a high‐risk population: a prospective, multicenter clinical study
Clinical evaluation of a multitarget fecal immunochemical test‐sDNA test for colorectal cancer screening in a high‐risk population: a prospective, multicenter clinical study Open
Colorectal cancer (CRC) is a major malignancy threatening the health of people in China and screening could be effective for preventing the occurrence and reducing the mortality of CRC. We conducted a multicenter, prospective clinical stud…
View article: LINC02582 Sponges MiR-375 To Promote The Lung Metastasis Of Colorectal Cancer Via Lactate Dehydrogenase B Dependent Glycolysis
LINC02582 Sponges MiR-375 To Promote The Lung Metastasis Of Colorectal Cancer Via Lactate Dehydrogenase B Dependent Glycolysis Open
Glycolysis plays significant roles in reprogramming the metastatic tumor microenvironment. Many lncRNAs have been reported to function as oncogenes by regulating glycolysis. In the present study, we found that the expression of LINC02582 g…
View article: Patient-derived organoids as a platform for drug screening in metastatic colorectal cancer
Patient-derived organoids as a platform for drug screening in metastatic colorectal cancer Open
Introduction: Most advanced colorectal cancers are aggressive, and there is a lack of effective methods for selecting appropriate anticancer regimens. Patient-derived organoids (PDOs) have emerged as preclinical platforms for modeling clin…
View article: Early Detection of Molecular Residual Disease and Risk Stratification for Stage I to III Colorectal Cancer via Circulating Tumor DNA Methylation
Early Detection of Molecular Residual Disease and Risk Stratification for Stage I to III Colorectal Cancer via Circulating Tumor DNA Methylation Open
Importance Detection of molecular residual disease and risk stratification as early as possible may improve the treatment of patients with cancer. Efficient pragmatic tests are therefore required. Objective To measure circulating tumor DNA…
View article: Newly developed 3D in vitro models to study tumor–immune interaction
Newly developed 3D in vitro models to study tumor–immune interaction Open
View article: Supplemental Figure Legend from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma
Supplemental Figure Legend from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma Open
Supplemental Figure 1
View article: Supplemental Figure Legend from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma
Supplemental Figure Legend from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma Open
Supplemental Figure 1
View article: Figure S1 from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma
Figure S1 from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma Open
Endogenous expression level of Gas1 in six colon cancer cells demonstrated by Western blot (A) and RT-PCR (B).
View article: Data from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma
Data from <i>Gas1</i> Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma Open
Growth arrest–specific 1 (Gas1) plays a critical role in growth suppression. Previous study indicated that Gas1 was closely associated with survival in patients with colorectal cancer; however, the underlying molecular mechanism remains un…
View article: Supplementary methods and figure legends from Circular RNA ciRS-7—A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer
Supplementary methods and figure legends from Circular RNA ciRS-7—A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer Open
Supplementary methods and figure legends
View article: Supporting Figure 2 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Supporting Figure 2 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential Open
PDF file 126K, PCA and OPLS-DA scores plot for CRC samples and adjacent non-tumor tissues collected from Hangzhou, Beijing and City of Hope
View article: Supplementary Information from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Supplementary Information from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential Open
PDF file 119K, This file includes supplementary text and figure legends for supporting figures
View article: Supporting Table 2 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Supporting Table 2 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential Open
PDF file 66K, Differentially expressed genes between CRC tissue and adjacent normal samples
View article: Supplementary Table 3 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer
Supplementary Table 3 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer Open
PDF file - 65K, Association between samples' characteristics and signature prediction outcomes.
View article: Supplementary Information from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Supplementary Information from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential Open
PDF file 119K, This file includes supplementary text and figure legends for supporting figures
View article: Supporting Table 3 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential
Supporting Table 3 from A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential Open
PDF file 50K, Treatment information for stage II and stage III patients in Shanghai cohort
View article: Supplementary Table 3 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer
Supplementary Table 3 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer Open
PDF file - 65K, Association between samples' characteristics and signature prediction outcomes.
View article: Supplementary Figure 1 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer
Supplementary Figure 1 from Identification and Validation of a Blood-Based 18-Gene Expression Signature in Colorectal Cancer Open
PDF file - 151K, On the heat map, red colors indicate genes upregulated and green colors indicate genes downregulated. Among the 263 genes, 179 were up-regulated and 84 were down-regulated in the cancer patients, respectively. On the hiera…